The Mouse Biology Shared Resource dedicates resources and expertise to support researchers participating in the UC Davis Cancer Center.
The following services are offered:
- Mouse Model Creation Services (generation of knockout and transgenic mouse strains, gene targeting by homologous recombination in ES cells, procurement, importation and rederivation to generate pathogen-free mice cryopreservation and resuscitation of embryos and germplasm, assisted reproduction procedures)
- Mouse Husbandry and Maintenance Services (colony management, health surveillance and disease prevention, sharing and distribution of strains)
- Mouse Phenotyping Services (gross and microscopic pathology, small animal imaging procedures)
The Mouse Biology Program coordinates the activities of a number of campus resources to serve researchers using genetically altered mice as models of human disease, including cancer. Resources include the Murine Targeted Genomics Laboratory, the "M3" Barrier Facility and "J1" Importation Facility, the Center for Laboratory Animal Science, the Mutant Mouse Pathology Laboratory, the Comparative Pathology Laboratory, the Small Animal Imaging Facility, the Murine Genetic Analysis Laboratory, the Murine Molecular Constructs Laboratory, the Murine Behavioral Assessment Laboratory, and the Mutant Mouse Regional Resource Center.