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Department of Pharmacology

Department of Pharmacology

Selected News Articles

 

June 2014
Angie Gelli, Ph.D.
Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease

Dr. Angie Gelli, Associate Professor, lead UC Davis investigators (Kiem Vu, Juhn Uhrig, Sarisa Na Pombejra, Mantana Jamklang, George Thompson III, Jennifer Bautos, and Rick Tham) in a remarkable series of experiments on Cryptococcus neoformans – the cause of a deadly meningitis -- to isolate a metalloprotease that appears to be responsible for the fungus’ ability to cross from the bloodstream into the brain. The findings were published in the journal mBio, issued by the American Society for Microbiology, in an article titled "Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease". The discovery has important implications for developing a more effective treatment for C. neoformans and other brain infections, as well as for brain cancers that are difficult to treat with conventional medications. To read more about this exciting discovery, go to News from UC Davis Health System newsroom.

March 2014
Science Signaling Journal
Ye Chen-Izu, Ph.D.
UC Davis researchers discover how high blood pressure damages the heart

Dr. Ye Chen-Izu, Assistant Professor in Pharmacology, pulled together an interdisciplinary team of biophysicists, chemists, engineers, physiologists and cardiologists for a study of the biological system that controls contractility of the heart under mechanical stress such as that caused by high blood pressure. Read about their recent study — "Mechanochemotransduction During Cardiomyocyte Contraction is Mediated by Localized Nitric Oxide Signaling" — published in the March 18 issue of the journal Science Signaling and available at http://stke.sciencemag.org/

December 2013
Pharmacology Holiday Party

Made possible by the generous support of our departmental faculty!

December 2013
Donald Bers, Ph.D.
Debrecen Award for Molecular Medicine

Dr. Donald Bers, the Department’s Distinguished Professor and Chair, was awarded the “2013 Debrecen Award for Molecular Medicine” from The Medical and Health Science Center of the University of Debrecen, Hungary. This international annual prize is offered to encourage and recognize extraordinary and sustained contributions to biomedical research. This prestigious prize is awarded to a scientist, or group, whose work has lead to significant advances in the fields of molecular medicine with demonstrated benefits applied to improved patient care. For more information about this award, please visit the Debrecen Award for Molecular Medicine’s website.

November 2013
Donald Bers, Ph.D.
34 from UC elected fellows of AAAS

Distinguished Professor and Chair, Don Bers, was elected as fellow of the American Association for the Advancement of Science (AAAS). He is 1 of 10 elected fellows for AAAS from the University of California at Davis. This honor is bestowed for scientifically distinguished efforts to advance science or its applications. Dr. Bers is being recognized for his innovative approaches in calcium signaling and integrative quantitative analysis that have built the modern framework of regulation of cardiac contractions and electrical activity. To read the full article, please go to UCDMC’s Spotlight, or view AAAS’ News.

September 2013
Donald Bers, Ph.D.
UC Davis researchers discover a biological link between diabetes and heart disease

Dr. Don Bers (Professor and Chair) and colleagues identified a novel molecular pathway between diabetic hyperglycemia and cardiac arrhythmias (online publication in Nature). Hyperglycemia chronically activates the key signaling kinase CaMKII by direct attachment of a sugar, causing CaMKII-dependent ion channel effects and arrhythmias (and potential effects on many systems.

June 2013
Florin Despa, Ph.D.
A second amyloid may play a role in Alzheimer's disease, UC Davis researchers find

Dr. Florin Despa and colleagues found that amylin accumulates in the blood vessels and and brain of patients with diabetes and dementia. Additional study authors are Kaleena Jackson, Gustavo A. Barisone, Elva Diaz and Lee-Way Jin, all of UC Davis.

May 2013
Johannes Hell, Ph.D.
And colleagues discovered that the structural protein α-actinin anchors CaV1.2 at the plasma membrane and especially in spines in neurons.

Professor Johannes Hell and colleagues discovered that the structural protein α-actinin anchors CaV1.2 at the plasma membrane and especially in spines in neurons. Read about this groundbreaking research in the journal Neuron.

2013
Heike Wulff, Ph.D.
Was awarded the 2013 Basic Sciences Kaiser Teaching Award

Dr. Heike Wulff, Associate Professor, was awarded the 2013 Basic Sciences Kaiser Teaching Award. The three recipients of this award were selected following requested nominations from students, residents and regular faculty of the School of Medicine and meet specified criteria, one of which is having a record of sustained excellence for at least three years.

April 2013
Angela Gelli, Ph.D.
Was awarded the 2012 Hartwell Individual Biomedical Research Award and designation as a Hartwell Investigator

Dr. Angela Gelli, Associate Professor, was awarded the 2012 Hartwell Individual Biomedical Research Award and designation as a Hartwell Investigator. Dr. Gelli’s winning research proposal represents innovative and cutting edge research that aims to develop a novel drug delivery system targeting the blood-brain barrier for the treatment of childhood brain tumors. To learn more about this honor, Please go to the Hartwell Foundation's website.

November 2012
Donald Bers, Ph.D.
UC Davis researcher recognized as distinguished scientist by the American Heart Association

Dr. Donald M. Bers, the Department’s Distinguished Professor and Chair, was awarded the American Heart Association/American Stroke Association's Distinguished Scientist designation in November 2012, for his contribution to cardiovascular research. To learn more about this honor, please view the American Heart Association’s website.

February 2012
Florin Despa, Ph.D.
Pancreatic hormone linked with severe heart disease in obese and diabetic patients

June 2010
Donald M. Bers, Ph.D.
UC Davis study eliminates a possible culprit in heart arrhythmia

January 2010
Elva Diaz, Ph.D.
UC Davis researchers identify brain protein for synapse development: Discovery could expand understanding of autism and schizophrenia

September 2009
Elva Diaz, Ph.D.

Elva Diaz receives NIH New Innovator funding

September 2009
David Segal, Ph.D. & Heike Wulff, Ph.D

Innovative, collaborative projects recognized with 2009 CTSC pilot grants

Peggy Farhnam, Ph.D.
Collaboration between Peggy Farnham and Janine LaSalle results in published study on Rett's Syndrome.

April 2009
Donald Bers, Ph.D.

Professor and Pharmacology Chairman Donald Bers is recipient of the Joseph Silva Dean's Endowed Chair in Cardiovascular Research

June 2008
Donald Bers, Ph.D.

UC Davis appoints renowned cardiovascular resercher as Pharmacology Department Chair

June 2007
Peggy Farnham, Ph.D.

Encyclopedia of DNA Published

November 2006
Heike Wulff, Ph.D.

New drugs aimed at T cells successfully treat arthritis and diabetes in rats