December 15, 2014
Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer. Too little Rbm38 allows p53 overexpression, causing premature aging. The study was published in the journal PNAS on Dec. 15.
December 11, 2014
The UC Davis Comprehensive Cancer Center will host a holiday party for pediatric cancer patients and their families on Saturday, Dec. 13.
November 13, 2014
Researchers at UC Davis and other institutions have found that diets rich in whole walnuts or walnut oil slowed prostate cancer growth in mice. In addition, both walnuts and walnut oil reduced cholesterol and increased insulin sensitivity.
November 12, 2014
UC Davis medical oncologist Jonathan Riess is the recipient of a 2014 Young Innovators Team Award for Lung Cancer Research, and will share a $500,000 for translational lung cancer research with two other physician-scientists.
November 10, 2014
UC Davis Medical Center is preparing to screen seniors on Medicare who meet the criteria for lung cancer screening using low-dose computed tomography (CT).
October 31, 2014
Treatment for early stage breast cancer is highly effective, and for many women considering treatment choices, chemotherapy may add little to an already high long-term survival rate. Joy Melnikow, professor in the Department of Family and Community Medicine and Director of the Center for Healthcare Policy and Research at UC Davis, is working to define the potential long-term harms of chemotherapy for these patients, so they can be weighed against the potential benefits.
October 28, 2014
The National Cancer Institute (NCI) has awarded a $2.7 million grant to UC Davis researchers to investigate how the so-called Western diet, which is high in fat and sugar, increases the risk of developing liver and gastrointestinal (GI) cancers. In addition, the researchers will study whether bifidobacteria, a common family of bacteria in the human gut, can be enriched to prevent cancer.
October 24, 2014
Researchers at UC Davis have found that the drug bortezomib effectively treats chronic graft-versus-host disease (GVHD), a common and debilitating side effect from allogeneic hematopoietic stem cell transplants.
October 21, 2014
Brad Pollock, a leading researcher on the incidence and control of childhood and adolescent cancer, has become chair of the Department of Public Health Sciences at the UC Davis School of Medicine.
October 21, 2014
The National Cancer Institute (NCI) has awarded UC Davis principal investigators Laura Marcu and Gregory Farwell $1.5 million to adapt UC Davis-developed biophotonic technology to a robotic surgical device in hopes of dramatically improving the precision of head and neck cancer surgery.
October 10, 2014
A multidisciplinary team at UC Davis will embark on research to determine whether combining a novel type of immunotherapy with radiation and chemotherapy can make treatment for sarcoma, breast and pancreatic cancers more effective.
September 24, 2014
The UC Davis Comprehensive Cancer Center’s Brain Innovation Group has received a grant from the National Cancer Institute (NCI) to improve brain cancer surgery and treatment using UC Davis-developed biophotonic technology.
September 11, 2014
Noriko Satake, UC Davis pediatric oncologist and researcher, has demonstrated in laboratory studies that a new, targeted treatment for leukemia is effective.
August 26, 2014
mKit Lam and colleagues from UC Davis and other institutions have created dynamic nanoparticles (NPs) that could provide an arsenal of applications to diagnose and treat cancer. Built on an easy-to-make polymer, these particles can be used as contrast agents to light up tumors for MRI and PET scans or deliver chemo and other therapies to destroy tumors. In addition, the particles are biocompatible and have shown no toxicity. The study was published online today in Nature Communications.
August 21, 2014
In a media briefing at the UC Davis Comprehensive Cancer Center, the American Cancer Society Cancer Action Network released How Do You Measure Up?, an annual report that scores each state on how they are doing in the fight against cancer.
August 11, 2014
Researchers at UC Davis, City of Hope, Taipai Medical University and National Health Research Institutes in Taiwan have discovered how a drug that deprives the cells of a key amino acid specifically kills cancer cells.
August 7, 2014
UC Davis Comprehensive Cancer Center oncologist Chong-Xian Pan has received a $650,000 grant from the VA Northern California Health Care System to conduct the first clinical trial of a novel chemotherapy-delivery drug he developed for bladder cancer patients.
July 18, 2014
No Stomach for Cancer Foundation (NSFC) has awarded cancer geneticist Luis Carvajal-Carmona a $50,000 grant to study the genetic characteristics of gastric cancer.
July 15, 2014
Researchers at UC Davis School of Medicine have for the first time shown that a polysialylated glycoprotein that regulates neurodevelopment exists on the surface of cells in the adult inner ear.
July 14, 2014
Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase (sEH) inhibitor, the drug controls angiogenesis (blood vessel formation), limiting a tumor’s ability to grow and spread. The study appears today in the journal Proceedings of the National Academy of Sciences.
July 10, 2014
When it comes to a specific type of pancreatic surgery, post-operative complications have a far greater impact on total cost than does how long the patient stays in the hospital, according to a published paper by UC Davis researchers.
June 26, 2014
Researchers at UC Davis have determined that surgical biopsies can be safely performed on select patients with late-stage non-small cell lung cancer, which should enhance their access to drugs that target specific genetic mutations such as epidermal growth factor receptor (EGFR).
June 24, 2014
A UC Davis program designed to better manage cancer patients taking oral chemotherapy drugs has demonstrated that one-on-one counseling, education and monitoring can improve adherence to potentially life-saving cancer treatments.
June 16, 2014
UC Davis Comprehensive Cancer Center patients will soon be part of an unprecedented clinical trial designed to improve access to promising therapies and speed development of effective treatments for an advanced form of lung cancer, the leading cancer killer of both men and women.
June 11, 2014
UC Davis Comprehensive Cancer Center researchers take center stage this week in Madrid during the second in a series of workshops designed to enhance cultural, academic, scientific and business relations between UC Davis and Madrid.
May 29, 2014
Paramita Ghosh, a UC Davis associate professor and expert in signal transduction pathways in prostate cancer, has been selected as one of 350 scientists to work on a project that aims to reduce public exposure to environmental agents that can lead to cancer and that hopes to inspire research into multi-faceted approaches to cancer prevention, treatment and prolonged survival.
May 12, 2014
Colorectal cancer screening saves lives, but too few people get tested. In an effort to increase these numbers,researchers from UC Davis and elsewhere investigated whether an individualized interactive multimedia computer program (IMCP) would spur patients to get screened.
April 17, 2014
An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process. This is the first time the complex has been shown to perform both jobs. This newfound ability could make cyclin B1/Cdk1 an excellent target to control cellular energy production, potentially advancing cancer care and regenerative medicine. The research was published online today in the journal Developmental Cell.
April 11, 2014
In an effort to reduce cancer health disparities among Asian-Americans, UC Davis Comprehensive Cancer Center now offers individual, in-language education and culturally sensitive materials for every Asian-American cancer patient.
March 26, 2014
Blood and tumor specimen collection from cancer patients is critical to research into new, more personally targeted therapies. But biospecimen collection among diverse populations lags far behind that of whites. [Chinese, Vietnamese and Spanish]
March 24, 2014
UC Davis professor Christopher Bowlus of the Division of Gastroenterology and Hepatology, and his liver cancer disparity research, are featured on the Health Equity Research Snapshot of the Association of American Medical Colleges (AAMC).
March 21, 2014
After nine years and countless fund-raising events, the Placer Breast Cancer Endowment on Thursday reached its goal of $1.5 million for breast cancer research at UC Davis Comprehensive Cancer Center.
March 20, 2014
Researchers at UC Davis have found that the investigational cancer vaccine tecemotide, when administered with the chemotherapeutic cisplatin, boosted immune response and reduced the number of tumors in mice with lung cancer. The study also found that radiation treatments did not significantly impair the immune response. The paper was published on March 10 in the journal Cancer Immunology Research, an American Association for Cancer Research (AACR) publication.
March 19, 2014
UC Davis clinicians and physicists have recommended new strategies to make computed tomography (CT) safer, including adoption of a new metric for dose measurement, ways to manage exposure protocols that differ by CT brand and specific approaches to reduce exposure during needle biopsies. The recommendations are detailed in papers published in the March issue of the Journal of the American College of Radiology (JACR).
March 18, 2014
Twenty years after Congress mandated that research funded by the National Institutes of Health include minorities, less than 5 percent of trials participants are non-white, and less than 2 percent of clinical cancer research studies focus on non-white ethnic or racial groups, UC Davis researchers have found. [Chinese, Spanish, Korean, Vietnamese]
March 18, 2014
A new study involving researchers from UC Davis and four other National Cancer Institute-designated cancer centers reveals important barriers that limit minority group participation in cancer clinical trials, findings that will be used to refine and launch more effective strategies to assure that more minorities benefit from clinical trials.
March 14, 2014
Several chemotherapy patients at the UC Davis Comprehensive Cancer Center will be invited to use tablets with a unique social networking tool as part of their treatment plan.
March 10, 2014
The hunt is on to find biomarkers that detect cancer, but it’s a challenging process. Early successes often are followed by heartbreaking failures.
March 7, 2014
Biomarkers for bone formation and resorption predict outcomes for men with castration-resistant prostate cancer, a team of researchers from UC Davis and their collaborators have found.
January 23, 2014
Bruce D. Hammock, UC Davis Distinguished Professor of Entomology, has received the 2014 Bernard B. Brodie Award from The American Society for Pharmacology and Experimental Therapeutics (ASPET).
January 23, 2014
James A. Purdy, UC Davis professor emeritus in the UC Davis Department of Radiation Oncology, has been given the Distinguished Alumnus Award from the University of Texas MD Anderson Cancer Center.