Video: Learn more about the expertise and resources offered to support Cancer Center researchers
from Kent Lloyd, director of the Mouse Biology Shared Resource.
The goal of Mouse Biology Shared Resource is to meet the needs of UC Davis Comprehensive Cancer Center investigators, utilizing genetically-altered mice for basic, clinical and translational research.
The Mouse Biology Shared Resource offers many services, including:
- Mouse Model Creation Services (generation of knockout and transgenic mouse strains, gene targeting by homologous recombination in embryonic stem (ES) cells, procurement, importation and rederivation to generate pathogen-free mice, strain cryopreservation and resuscitation, assisted reproduction procedures)
- Mouse Husbandry and Maintenance Services (colony management, health surveillance and disease prevention, sharing and distribution of strains)
- Mouse Phenotyping Services (gross and microscopic pathology, small animal imaging procedures)
The Mouse Biology Program coordinates the activities of a number of campus resources to serve researchers using genetically altered mice as models of human disease, including cancer. Resources include the Murine Targeted Genomics Laboratory, the "M3" Barrier Facility and "J1" Importation Facility, the Center for Laboratory Animal Science, the Mutant Mouse Pathology Laboratory, the Comparative Pathology Laboratory, the Small Animal Imaging Facility, the Murine Genetic Analysis Laboratory, the Murine Molecular Constructs Laboratory, the Murine Behavioral Assessment Laboratory, the Mutant Mouse Regional Resource Center and Knock Out Mouse Project Repository.