Recent/Current
Research Funding

American Heart
Association

Nora Eccles Treadwell
Foundation

Philip Morris

Graduate Group Affiliations

Biophysics

Molecular, Cellular and
Integrative Physiology

Research Interests

• Immune cell function 
• Membrane trafficking and fusion
• Endocytosis/exocytosis
• Intracellular Ca2+ signaling
• Ion channels

For more research information please see: Fomina Lab Home Page 

Representative Publications

Fomina, A.F., Kostyuk, P.G., and Sedova M.B. 1993. Glucocorticoids modulation of calcium currents in GH3 cells. Neuroscience 55:721-725.

Takimoto, K., Fomina, A., Gealy, R., Trimmer, J.S., and Levitan, E.S. 1993. Dexamethasone rapidly induces Kv 1.5 K+ channel gene transcription and expression in clonal pituitary cells. Neuron 11: 359-396.

Fomina, A. and Levitan, E.S. 1995. Three phases of TRH-induced facilitation of exocytosis by single lactotrophs. J. Neurosci. 15: 4982-4991.

Takimoto, K., Gealy, R., Fomina, A.F., Trimmer, J.S., and Levitan, E.S. 1995.

Inhibition of voltage-gated K channel gene expression by the neuropeptide thyrotropin releasing hormone. J. Neurosci. 15: 449-457.

Fomina, A.F., Takimoto, K., and Levitan, E.S. 1996. Dexamethasone rapidly increases calcium channel subunit messenger RNA expression and high voltage-activated calcium current in clonal pituitary cells. Neuroscience 72:857-862.

Fomina, A.F. and Levitan, E.S. 1997. Control of Ca channel current and exocytosis in rat lactotrophs by basally active protein kinase C and calcineurin. Neuroscience 78:523-531.

Fomina, A.F., and Nowycky, M.C. 1999. A current activated on depletion of intracellular Castores can regulate exocytosis in adrenal chromaffin cells. J. Neurosci. 19: 3711-3722.

Fomina, A.F., Fanger, C.M., Kozak J.A., and Cahalan, M.D. 2000. Single channel properties and regulated expression of Ca Release-activated Ca (CRAC) channels in human T cells. J. Cell Biol., 151: 1435-1444.

Fomina A. F., Deerinck, T., Ellisman, M., and Cahalan, M.D. 2003. Visualization of membrane trafficking with FM1-43 reveals different endocytic pathways in resting and activated T cells. Exp. Cell Res. 291: 150-166.

Dadsetan, S., Shishkin, V., and Fomina A. F. 2005. Intracellular Ca²⁺ release triggers translocation of membrane marker FM1-43 from the extracellular leaflet of the plasma membrane into endoplasmic reticulum in T lymphocytes. J.Biol. Chem. 280: 16377–16382.

Semenova, S.B., Fomina, A.F, Vassilieva, I.O., and Negulyaev, Y.A., 2005. Properties of Mg - dependent cation channels in human leukemia K562 cells. J. Cell. Physiol. 205:372-8.

Zakharova, L., Svetlova M., and Fomina A.F.,2006. T cell Exosomes induce cholesterol accumulation in monocytes via phosphatidyl serine receptor. J. Cell. Physiol. 212: 174-181.

Dadsetan, S., Zakharova, L., Molinski, T.F., and Fomina A.F. Store-operated Ca²⁺ influx causes Ca²⁺ release from the intracellular Ca²⁺ channels that is required for T cell activation. J. Biol. Chem. 2008 May 2;283(18):12512-12519.

Chen, H., Dadsetan, S., Fomina, A.F., and Gong, Qizhi. Expressing exogenous functional odorant receptors in cultured olfactory sensory neurons. Neural Development 2008, 3(1): 22.

Zakharova L., Dadsetan, S., and Fomina, A.F. (2009). Endogenous Jmjd6 gene product is expressed at the cell surface and regulates phagocytosis in immature monocyte-like activated THP-1 cells. J.Cell. Physiol. In press.

Semenova, S.B., Vassilieva, I.O., Fomina, A.F, and Negulyaev, Y.A. (2009). Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells. Am J. Physiol. Cell Physiol. In Press.

Recent/Current Teaching

HPH199, Special Study Research
BPH200B, Current Techniques in Biophysics
HPH210A, Advanced Physiology
HPH418, Mammalian Endocrinology
HPH400, Human Physiology
IMD405, MERN: Metabolism, Endocrinology, Reproduction, Nutrition
MCB/BPH241, Membrane Biology
MCP290, Distinguished lectures in Physiology and Membrane Biology
MPC299, Special Study