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Department of Physiology and Membrane Biology

Department of Physiology and Membrane Biology

Carroll Cross, M.D.

Carroll Cross, M.D.

Professor
Professional Services Building
Sacramento Campus
(916) 453-2287
e-mail

Recent/Current Research Funding

National Institutes of Health

Graduate Group Affiliations

Molecular, Cellular, and Integrative Physiology

Agricultural and Environmental Chemistry

Research Interests

Dr. Cross’s expertise is in the areas of oxidative stress and respiratory tract biology with a focus on environmental inhaled oxidant exposures (e.g. ozone, cigarette smoke) and respiratory tract inflammation-related oxidants as best exemplified by cystic fibrosis.

 

Representative Publications

2010  Yoneda KY, Cross CE. The pulmonary toxicity of anticancer agents. In Comprehensible Toxicology, Chapter 25. 3nd ed, vol 9, toxicology of the Respiratory Tract, GS Yost, Editor, In Press. 2010

2010  Vasu VT, Oommen S, Lim Y, Valacchi G, Hobson B, Eirserich JP, Leonard SW, Traber MG, Cross CE, Gohil K. Modulation of ozone-sensitive genes in alpha-tocopherol transfer protein null mice. Inhal Toxicol 22(1):1-16. 2010

2009  Vasu VT, Cross CE, Gohil K. Nr1d1, an important circadian pathway regulatory gene, is suppressed by cigarette smoke in murine lungs. Integr Cancer Ther 8(4):321-8. 2009

2009  Aung HH, Vasu VT, Valacchi G, Corbacho AM, Kota RS, Lim Y, Obermueller-Jevic UC, Packer L, Cross CE, Gohil K. Effects of dietary carotenoids on mouse lung genomic profiles and their modulatory effects on short-term cigarette smoke exposures. Genes Nutr 4(1):23-39. 2009

2008  Lim Y, Vasu VT, Valacchi G, Leonard S, Aung HH, Schock BC, Kenyon NJ, Li CS, Traber MG, Cross CE. Severe vitamin E deficiency modulates airway allergic inflammatory responses in the murine asthma model. Free Radic Res. 42(4):387-96. 2008

2007  Beattie JR, Maguire C, Gilchrist S, Barrett LJ, Cross CE, Possmayer F, Ennis M, Elborn JS, Curry WJ, McGarvey JJ, Schock BC. The use of Raman microscopy to determine and localize vitamin E in biological samples. FASEB J 21(3):766-76. 2007

2007  Gohil K, Oommen S, Vasu VT, Aung HH, Cross CE. Tocopherol transfer protein deficiency modifies nuclear receptor transcriptional networks in lungs: modulation by cigarette smoke in vivo. Mol Aspects Med 28(5-6):453-80. 2007

2007  Oommen S, Vasu VT, Leonard SW, Traber MG, Cross CE, Gohil K. Genome wide responses of murine lungs to dietary alpha-tocopherol. Free Radic Res 41(1):98-109. 2007

2007  Cantin AM, White TB, Cross CE, Forman HJ, Sokol RJ, Borowitz D. Antioxidants in cystic fibrosis. Free Radic Biol Med 42(1):15-31. 2007

2006  Cross CE, Vasu VT, Lim Y, Gohil K. Combating oxidative stress at respiratory tract biosurfaces: challenges yet to be resolved, a commentary on "Vitamin supplementation does not protect against symptoms in ozone-responsive subjects". Free Radic Biol Med 40(10):1693-7. 2006

2000  Van Der Vliet A, Nguyen MN, Shigenaga MK, Eiserich JP, Marelich GP, Cross CE. Myeloperoxidase and protein oxidation in cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 279(3):L537-46. 2000

1998  Eiserich JP, Hristova M, Cross CE, Jones AD, Freeman BA, Halliwell B, van der Vliet A. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 391(6665):393-7. 1998