Residency : Vidya matched for her residency in Internal Medicine at the Albert Einstein/Montefiore Medical Center in Bronx, New York in 2015
Alma Mater: University of California, San Diego
Thesis Advisor: Renee Tsolis, Ph.D.
Graduate Group: Microbiology
Research Project: n/a
Kerrinnes T, Young BM, Leon C, Roux CM, Tran L, Atluri VL, Winter MG, Tsolis RM. “Phospholipase A1 modulates the cell envelope phospholipid content of Brucella melitensis, contributing to polymyxin resistance and pathogenicity.” Antimicrob Agents Chemother. 2015 Nov.
Winter SE, Winter MG, Atluri VL, Poon V, Romão EL, Tsolis RM, Bäumler AJ. “The flagellar regular TviA reduces pyroptosis by Salmonella enterica serovar Typhi.” Infect Immun. 2015 Apr.
Silva TM, Mol JP, Winter MG, Atluri V, Xavier MN, Pires SF, Paixão TA, Andrade HM, Santos RL, Tsolis RM. “The predicted ABC transporter AbcEDCBA is required for type IV secretion system expression and lysosomal evasion by Brucella ovis.” PloS One. 2014 Dec 4.
Patra KP, Saito M, Atluri VL, Rolán HG, Young B, Kerrinnes T, Smits H, Ricaldi JN, Gotuzzo E, Gilman RH, Tsolis RM, Vinetz JM. “A protein-conjugate approach to develop a monoclonal antibody-based antigen detection test for the diagnosis of human brucellosis.” PloS Negl Trop Dis. 2014 Jun 5.
Xavier MN, Winter MG, Spees AM, den Hartigh AB, Nguyen K, Roux CM, Silva TM, Atluri VL, Kerrinnes T, Keestra AM, Monack DM, Luciw PA, Eigenheer RA, Bäumler AJ, Santos RL, Tsolis RM. “PPARy-mediated increase in glucose availability sustains chronic Brucella abortus infection in alternatively activated macrophages.” Cell Host Microbe. 2013 Aug 14.
Xavier MN, Winter MG, Spees AM, Nguyen K, Atluri VL, Silva TM, Bäumler AJ, Müller W, Santos RL, Tsolis RM. “CD4+ T cell-derived IL-10 promotes Brucella abortus persistence via modulation of macrophage function.” PloS Pathog. 2013.
Terwagne M, Ferooz J, Rolán HG, Sun YH, Atluri VL, Xavier MN, Franchi L, Núñez G, Legrand T, Flavell RA, De Bolle X, Letesson JJ, Tsolis RM. “Innate immune recognition of flagellin limits systemic persistence of Brucella.” Cell Microbiol. 2013 Jun.
Cannella AP, Lin JC, Liang L, Atluri VL, Gotuzzo E, Felgner PL, Tsolis RM, Vinetz JM. “Serial kinetics of the antibody response against the complete Brucella melitensis ORFeome in focal vertebral brucellosis.” J Clin Microbiol. 2012 Mar.
Atluri VL, Xavier MN, de Jong MF, den Hartigh AB, Tsolis RM. “Interactions of the human pathogenic Brucella species with their hosts.” Annu Rev Microbiol. 2011. Review
Paschos A, den Hartigh A, Smith MA, Atluri VL, Sivanesan D, Tsolis RM, Baron C. “An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation.” Infect Immun. 2011 Mar.
Liang L, Leng D, Burk C, Nakajima-Sasaki R, Kayala MA, Atluri VL, Pablo J, Unal B, Ficht TA, Gotuzzo E, Saito M, Morrow WJ, Liang X, Baldi P, Gilman RH, Vinetz JM, Tsolis RM, Felgner PL. “Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella meltiensis antigens.” PloS Negl Trop Dis. 2010 May 4.
Residency: Samir began his residency at Harvard Longwood Psychiatry Facility in Boston, Massachusetts in 2015
Alma Mater: Massachusetts Institute of Technology
Thesis Advisor: Dennis Matthews, Ph.D.
Graduate Group: Biomedical Engineering
Awasthi S, Izu LT, Mao Z, Jian Z, Landas T, Lerner A, Shimkunas R, Woldeyesus R, Bossuyt J, Wood B, Chen YJ, Matthews DL, Lieu DK, Chiamvimonvat N, Lam KS, Chen-Izu Y, Chan JW. “Multimodal SHG-2PF Imaging of Microdomain Ca2+-Contraction Coupling in Live Cardiac Myocytes.” Circ Res. 2016 Jan 22. Review.
Collier BB, Awasthi S, Lieu DK, Chan JW. “Non-linear optical flow cytometry using a scanned, Bessel bean light-sheet.” Sci Rep. 2015 May 29.
Awasthi S, Matthews DL, Li RA, Chiamvimonvat N, Lieu DK, Chan JW. “Label-free identification and characterization of human pluripotent stem cell-derived cardiomyocytes using second harmonic generation (SHG) microscopy.” J Biophotonics. 2012 Jan.
Research Project: (1-2 sentences):
We are developing a label-free, non-invasive cell sorter capable of purifying stem cell-derived cardiomyocytes (SC-CMs) from the mixture of cells that results from a typical embryoid body or directed differentiation protocol. The technology is based off of second harmonic generation (SHG), a nonlinear optical process that occurs quite strongly in sarcomeric myosin. We are also using SHG to image the contractile dynamics of immature SC-CMs.
Presentations: Optics Within Life Sciences 2010 (Quebec City, QC, Canada). "Second
harmonic generation (SHG) microscopy of stem cell derived
SPIE Photonics West: BIOS 2011 (San Francisco, CA). "Characterization
of stem cell derived cardiomyocytes using second harmonic generation
Carolyn Zenith Black
Residency: PM&R at Harvard Spaulding Rehab Hospital, preceded by Medicine Prelim at UCSF-Fresno.
Alma Mater: University of Maryland, Baltimore County
Thesis Advisor: Lisa A. Miller
PSTP Advisor: Rick Harper
Graduate Group: BMCDB
Research Project: Effects of air pollution on the developing immune system
Hobbies: Running, backpacking, climbing
UC San Francisco-Fresno-CA
Phys Medicine & Rehab 1260340A0
Harvard Spaulding Rehab Hosp-MA
Residency: Ophthalmology University of Iowa, Iowa City [didn't realize that "ranks among the best in Ophthalmology Times and U.S. News and World Report"]
Alma Mater: University of California, Davis
Thesis Advisor: Marie Burns
PSTP Advisor: Saul Schaefer
Graduate Group: BMCDB
U Iowa Hosps and Clinics
IOWA CITY, IA
IOWA CITY, IA
Speeding rod recovery improves temporal resolution in the retina. Vision Res. 2015 May;110(Pt A):57-67. doi: 10.1016/j.visres.2015.02.011. Epub 2015 Mar 5.
PSTP Advisor: John Payne
Graduate Group: BMCDB
Hammond E, Lang J, Maeda Y, Pleasure D, Angus-Hill M, Xu J, Horiuchi M, Deng W, Guo F. “The Wnt effector transcription factor 7-like 2 positively regulates obligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling.” J Neurosci. 2015 Mar 25.
Guo F, Lang J, Sohn J, Hammond E, Chang M, Pleasure D. “Canonical Wnt signaling in the obligodendroglial lineage—puzzles remain.” Glia. 2015 Oct. Review.
Sequerra EB, Cates S, Moreno M, Lang J, Orosco LA, Spencer K. “Endocannabinoid signaling alters internal programming of neuronal fate specification.” J Neurosci. 2013 Mar 27.
Lang J, Maeda Y, Bannerman P, Xu J, Horiuchi M, Pleasure D, Guo F. “Adenomatous polyposis coli regulates obligodendroglial development.” J Neurosci. 2013 Feb 13.
Sohn J, Selvaraj V, Wakayama K, Orosco L, Lee E, Crawford SE, Guo F, Lang J, Horiuchi M, Zarbalis K, Itoh T, Deng W, Pleasure D. “PEDF is a novel oligodendrogenic morphogen acting on the adult SVZ and corpus callosum.” J Neurosci. 2012 Aug 29.Tomimatsu T, Lee SJ, Peña JP, Ross JM, Lang J, Longo LD. “Maternal caffeine administration and cerebral oxygenation in near-term fetal sheep.” Peprod Sci. 2007 Sep.
Residency: Weston is a resident in Pediatrics at University of Washington Affiliated Hospitals in Seattle, Washington.
Alma Mater: Princeton University
Thesis Advisor: Janine LaSalle, Ph.D.
Graduate group: BMCDB
My research project involves looking at Neurodevelopmental diseases, chromatin structure and remodeling during development, RNA metabolism and trafficking, mechanisms of imprinting
Powell, Weston T., Rochelle L. Coulson, Florence K. Crary, Spencer S. Wong, Robert A. Ach, Peter Tsang, N. Alice Yamada, Dag H. Yasui, and Janine M. Lasalle. 2013. “A Prader-Willi Locus lncRNA Cloud Modulates Diurnal Genes and Energy Expenditure.” Human Molecular Genetics 22 (21) (November 1): 4318–28.
Powell, Weston T., Rochelle L. Coulson, Michael L. Gonzales, Florence K. Crary, Spencer S. Wong, Sarrita Adams, Robert A. Ach, et al. 2013. “R-Loop Formation at Snord116 Mediates Topotecan Inhibition of Ube3a-Antisense and Allele-Specific Chromatin Decondensation.” Proceedings of the National Academy of Sciences of the United States of America 110 (34) (August 20): 13938–43. Lasalle, Janine M., Weston T. Powell, and Dag H. Yasui. 2013. “Epigenetic Layers and Players Underlying Neurodevelopment.” Trends in Neurosciences 36 (8) (August): 460–70.
Powell, Weston T., and Janine M. LaSalle. 2013. “Imprinting in the CNS and Neurodevelopmental Disorders.” In Epigenetic Regulation in the Nervous System, edited by J. David Sweatt, Michael J. Meaney, Eric J. Nestler, and Schahram Akbarian, 267–279. Academic Press.
Meguro-Horike, Makiko, Dag H. Yasui, Weston Powell, Diane I. Schroeder, Mitsuo Oshimura, Janine M. Lasalle, and Shin-Ichi Horike. 2011. “Neuron-Specific Impairment of Inter-Chromosomal Pairing and Transcription in a Novel Model of Human 15q-Duplication Syndrome.” Human Molecular Genetics 20 (19): 3798–3810.
Powell WT, LaSalle JM. “Epigenetic mechanisms in dilurnal cycles of metabolism and neurodevelopment.” Hum Mol Genet. 2015 Oct 15.
Powell WT, Coulson RL, Gonzales ML, Crary FK, Wong SS, Adams S, Ach RA, Tsang P, Yamada NA, Yasui DH, Chédin F, LaSalle JM. “R-Loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.” Proc Natl Acad Sci U.S.A. 2013 Aug 20.
Fellowships and Awards: 2011-2013
NINDS Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows in MD-PhD programs (F31). Award F31NS073164. March 2013 2013 Max Kleiber Graduate Research Prize. Awarded annually in recognition of the most outstanding dissertation in the areas of nutrition and metabolism. November 2012 2012 ASHG/Charles J. Epstein Trainee Award for Excellence in Human Genetics Research. Awarded at the annual ASHG meeting for excellence in research presented.
Residency: Nicolas's first transitional residency program was at Santa Clara Valley Medical Center. His second program, in Radiation Oncology, is at Stanford University.Alma Mater: Stanford University
Thesis Advisor: John M. Boone, Ph.D.
Graduate Group: Biomedical Engineering
Publications - UC Davis:
N. D. Prionas, S. Y. Huang and J. M. Boone, "Experimentally determined spectral optimization for dedicated breast computed tomography," Med Phys 38, 646-655 (2011).
N. D. Prionas, K. K. Lindfors, S. Ray, S. Y. Huang, L. A. Beckett, W. L. Monsky and J. M. Boone, "Contrast-enhanced dedicated breast CT: initial clinical experience," Radiology 256, 714-723 (2010).
N. D. Prionas, S. Ray and J. M. Boone, "Volume assessment accuracy in computed tomography: a phantom study," J Appl Clin Med Phys 11, 3037 (2010).
N. D. Prionas, M. A. Gillen and J. M. Boone, "Longitudinal volume analysis from computed tomography: Reproducibility using adrenal glands as surrogate tumors," J Med Phys 35, 174-180 (2010).
S. Y. Huang, J. M. Boone, K. Yang, N. J. Packard, S. E. McKenney, N. D. Prionas, K. K. Lindfors and M. J. Yaffe, "The characterization of breast anatomical metrics using dedicated breast CT," Medical Physics 38, 2180-2191 (2011).
Aminololama-Shakeri S, Abbey CK, Gazi P, Prionas ND, Nosratieh A, Li CS, Boone JM, Lindfors KK. “Differentiation of ductal carcinoma in-situ from benign micro-calcifications by dedicated breast computed tomography.” Eur J Radiol. 2016 Jan.
Prionas ND, Burkett GW, McKenney SE, Chen L, Stern RL, Boone JM. “Development of a patient-specific two-compartment anthropomorphic breast phantom.” Phys Med Biol. 2012 Jul 7.
Katzberg RW, Monsky WL, Prionas ND, Sidhar V, Southard J, Carlson J, Boone JM, Lin TC, Li CS. “Persistent CT nephrograms following cardiac catheterization and intervention: initial observations.” Insights Imaging. 2012 Feb.
Prionas ND, McKenney SE, Stern RL, Boone JM. “Kilovoltage rotational external beam radiotherapy on a breast computed tomography platform: a feasibility study.” Int J Radiat Oncol Biol Phys. 2012 Oct 1.
Huang SY, Boone JM, Yang K, Packard NJ, McKenney SE, Prionas ND, Lindfors KK, Yaffe MJ. “The characterization of breast anatomical metrics using dedicated breast CT.” Med Phys. 2011 Apr.
Residency: Can matched for his residency in Internal Medicine at Barnes-Jewish Hospital in St Louis, MO in 2016.Alma Mater: Macalester College
Thesis Advisor: William J. Murphy
PSTP Advisor: Charles Bevins
Graduate Group: Immunology
Sckisel GD, Bouchlaka MN, Monjazeb AM, Crittenden M, Curti BD, Wilkins DE, Alderson KA, Sungur CM, Ames E, Mirsoian A, Reddy A, Alexander W, Soulika A, Blazar BR, Longo DL, Wiltrout RH, Murphy WJ. “Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity.” Immunity. 2015 Aug 18.
Alvarez M, Bouchlaka MN, Sckisel GD, Sungur CM, Chen M, Murphy WJ. “Increased antitumor effects using IL-2 with anti-TGF-β reveals competition between mouse NK and CD8 T cells.” J Immunol. 2014 Aug 15.
Sungur CM, Murphy WJ. “Positive and negative regulation by NK cells in cancer.” Crit Rev Oncog. 2014. Review.
Sungur CM, Murphy WJ. “Utilization of mouse models to decipher natural killer cell biology and potential clinical applications.” Hematology Am Soc Hematol Educ Program. 2013. Review.
Barao I, Wright PW, Sungur CM, Anderson SK, Redelman D, Murphy WJ. “Differential expression of the Ly49G (B6) , but not the Ly49G(BALB), receptor isoform during natural killer cell reconstitution after hematopoietic stem cell transplantation.” Biol Blood Marrow Transplant. 2013 Oct.
Residency: Radiology at Brigham and Women's Hospital, preceded by Medicine Prelim at Ca Pacific Medical Center
Alma Mater: Stanford University
Thesis Advisor: Katherine Ferrara
PSTP Advisor: Katherine Ferrara
Graduate Group: Biomedical Engineering
CA Pacific Med Center
SAN FRANCISCO, CA
Brigham & Womens Hosp-MA
My research project is in image guided drug delivery, using imaging to study and facilitate the targeting of drug carrying nanoparticles to their site of action.