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Department of Biochemistry and Molecular Medicine

Department of Biochemistry and Molecular Medicine

Su Hao Lo, Ph.D.

Su Hao Lo, Ph.D.

Research I Room 3002
Ph: (916) 734-3656

Research Interests

Signal transduction mediated through focal adhesions and their roles in tissue and disease development


Representative Publications

Liao, Y. C., Chen, N. T., Shih Y. P., Dong, Y., Lo, S. H. Up-regulation of C-terminal tensin-like molecule promotes the tumorigenicity of colon cancer cells through b-catenin. Cancer Res 2009, 69:4563- 4566.

Lin, Y., Chen, N. T., Shih, Y. P., Liao, Y. C., Xue, L., and Lo, S. H, DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration. Oncogene 2010, 29:3010-3016

Shih, Y.P., Liao, YC., Lin, Y., Lo, S. H. DLC1 negatively regulates angiogenesis in a paracrine fashion. Cancer Res 2010, 70:8270-8275.

Shih Y.P., Takada, Y., Lo, S.H. Silencing of DLC1 promotes PAI-1 expression and reduces normal cell migration. Mol Cancer Res. 2012, 10:34-39.

Li, J.R., Shi, L., Deng, Z., Lo, S. H., Liu, G.Y. Nanostructures of Designed Geometry and Functionality Enable Regulation of Cellular Signaling Processes. Biochemistry 2012, 51, 5876–5893

Shi L, Li, J.R., Shih, Y.P., Lo, S. H., Liu, G. Y., Nanogratings of Fibronectin Provide an Effective Biochemical Cue for Regulating Focal Adhesion and Cellular Structure. Nano Res 2012, 8): 565–575

Hong, S. Y., Shih, Y. P., Li, T., Carraway, K., Lo, S.H. CTEN Prolongs Signaling by EGFR through Reducing Its Ligand-Induced Degradation. Cancer Res. 2013, 73(16):5266-76.

Lo. S.H. C-terminal tensin-like (CTEN): a promising biomarker and target for cancer. J Biochem Cell Biol. 2014, 51:150-4.


Recent/Current Teaching

Upper division courses

  • 192 Internship in Biological Chemistry
  • 198 Group Study
  • 199 Special Study for Advanced Undergraduates

Graduate courses

  • 209 Prostaglandins/Leukotrienes and Related Lipids (offered even years)
  • 214 Molecular Medicine
  • 217 Molecular Genetics of Fungi (odd years)
  • 222 Mechanisms of Translational Control (even years)
  • 230 Practical NMR
  • 231 Biomedical NMR (same as BPH 231)
  • 291 Human Genetics Seminar
  • 298 Group Study
  • 299 Research

Professional courses for medical students

  • 410A Molecular and Cell Biology
  • 410B Cell Biology and Metabolism
  • 414 Molecular Medicine
  • 491 Human Genetics Seminar
  • 497 Tutoring in Biological Chemistry
  • 498 Group Study
  • 499 Research