Leighton Izu, Ph.D.

Leighton Izu, Ph.D.

Specialties

Pharmacology

Department

Pharmacology

Title

  • Associate Professor
To see if Leighton Izu is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

Genome and Biomedical Sciences Building

451 Health Sciences Drive, Suite 3503
Davis, CA 95616
Driving Directions

Primary Phone:
530-752-3200

Additional Phone Numbers

Phone: 530-752-0324

Emails

Personal:
ltizu@ucdavis.edu

Research/Academic Interests

1. Effect of spatial distribution of molecules on cellular dynamics. We are particularly interested in how subtle spatial redistribution of ryanodine receptors, brought on by changes in myofilament Ca2+ sensitivity, alters the stability of the Ca2+ control system. An understanding of the interaction of the mechanical and Ca2+ control systems might provide insight into why patients with familial hypertrophic cardiomyopathy are at a high risk of sudden cardiac death.

2. Inverse methods. Drugs or mutations can affect many cellular subsystems. We are using inverse methods to identify the cellular targets of these drugs or mutations. Once identified, targeted experiments can be carried out to test whether the putative targets are in fact affected by the drug or mutation directly or indirectly. 

Education

Ph.D., State University of New York at Buffalo, Buffalo NY

B.A., University of Hawaii at Manoa, Manoa HI

Select Recent Publications

See: Complete List of Publications