March 2024 – Presented by Dr. Hang Mieu Ha (Mentored by Dr. Morgan Darrow)
A 76-year-old male with chronic sinusitis presents for evaluation of 6 months of ongoing epistaxis and anosmia. He reports a history of a hematologic malignancy and a remote left thalamic infarct leading to right hemiparesis and hemiplegia.
Head CT shows a polypoid mass in the left anterior skull base:
Following nasal endoscopy and diagnostic biopsy, resection of the mass and anterior skull base was performed.
Histologic sections of the resection show the following:
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Immunohistochemical studies were performed:
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Tumor cells show negative staining for AE1/AE3, CD45, and HMB45.
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