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Department of Pathology and Laboratory Medicine

Department of Pathology and Laboratory Medicine

Residency Program - Case of the Month

September 2013 - Presented by Michael Van Ness, M.D.


Clinical history:

The patient is a healthy 80yrs old male with a large, right, painless scrotal swelling that has progressed in size slowly for many years. The following tumor biomarkers were performed and found to be negative: AFP, LDH, betaHCG. Scrotal ultrasound demonstrated a right paratesticular mass without involvement of testis.


Gross description:

Received was a large, circumscribed, most encapsulated 12.1 x 10.3 x 7.2 cm mass that revealed a yellow, homogenous, fatty cut surface.


Microscopic description:

H&E stained sections shows mixtures of mature adipose tissue with mild variation in adipocyte size and fibrous tissue with areas of fine and coarse collagen. Rare atypical cells were located in fibrous areas and near or in the walls of blood vessels. No lipoblasts were identified.


Immunohistochemistry stains:

P16:          Positive (not provided)
CDK4:      Negative (not provided)
MDM2:      Negative (not provided)


Microscopic photographs:

Image 1      Image 2
     
Image 3   Image 4



Images:

Image 5   Image 6


Answer