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Department of Pathology and Laboratory Medicine

Department of Pathology and Laboratory Medicine

Residency Program - Case of the Month

April 2011 - Presented by Aram Millstein, M.D.

Clinical history:

The patient is a 38 year old male with a history of a left testicular varicocele and a chief complaint of infertility for four years. He had no other significant past medical or surgical history. A scrotal ultrasound done as part of the work up for infertility, showed a 0.5 cm hypoechoic mass in the right testicle, along with the varicocele in the left testicle. The radiologist noted that the right testicular mass was worrisome for a seminoma. A right radical orchiectomy was performed and the orchiectomy specimen is described below.

 

Gross description:

The right orchiectomy specimen consisted of a 4.2 x 2.2 x 1.9 cm testicle with attached 8 cm long spermatic cord. The tunica vaginalis was intact. Sectioning of the testicle revealed spongy, brown to yellow testicular parenchyma containing a 0.5 cm pale area. The histology of this area is shown below.

 

Microscopic photographs:

 

Immunihistochemistry

Figure 4. Desmin

Figure 5. Inhibin

Figure 6. CD30

Figure 7. CAM 5.2

Figure 8. Synaptophysin

Figure 9. Vimentin

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