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UC Davis Spine Center

UC Davis Spine Center

Current studies and clinical trials

  1. Randomized, Third-Party Blinded, Multicenter, Clinical Trial to Determine the Safety and Effectiveness of Oxiplex®/SP Gel for the Reduction of Pain and Symptoms Following Lumbar Disc Surgery
    (PI: Kee Kim. M.D.)

    The primary objective of this pivotal study is to evaluate the efficacy of Oxiplex®/SP Gel in the reduction of postoperative pain and symptoms and to evaluate the safety of applying Oxiplex®/SP Gel during single-level spinal discectomy performed to reduce symptoms associated with unilateral herniation of a lumbar intervertebral disc, in subjects undergoing their first surgeries for such conditions. The level of response in the treated and non-treated subject groups will be evaluated.

  2. A Multi-Center Study to Evaluate the Effect of Minimally Invasive vs. Open Posterolateral Lumbar Fusion on the Paraspinal Musculature Using High Resolution Structural and Quantitative MR Imaging
    (PI: Kee Kim, M.D.)

    The objective of this study is to evaluate paraspinal muscle damage following posterolateral lumbar fusion with the minimally invasive Atavi System versus traditional open surgery. We will use high resolution structural and quantitative MR imaging. Quantitative T2 scores and edema scores of the multifidus muscle will be used as microstructural indicators of muscle damage. The MRI will be done at the UC Davis Imaging Research Center.

  3. A Prospective, Multi-Center, Randomized Controlled Study to Compare the Spinal Sealant System as an Adjunct to Suture Dural Repair to Standard Sutured Repair During Spinal Surgery
    (PI: Kee Kim, M.D.)

    This is a prospective, multi-center, randomized, two-arm, single-blind study designed to assess if the Spinal Sealant System, when used in addition to sutured dural repair, is more effective than standard-of-care methods for producing a watertight dural closure in patients undergoing an intentional durotomy during spinal surgery.

  4. A Multi-Center, Prospective, Randomized, Controlled Clinical Trial Comparing the Safety and Effectiveness of the Mobi-C Prosthesis to Conventional Anterior Cervical Discectomy and Fusion in the Treatment of Symptomatic Degenerative Disc Disease in the Cervical Spine
    (PI: Kee Kim, M.D.)

    Mobi-C® Prosthesis Cervical Disc is a second-generation artificial disc designed for patients who have one- or two-level degenerative disc disease and who have failed conservative treatment of at least six weeks.

    This research study is being performed to determine the safety and effectiveness of the Mobi-C® Prosthesis Cervical Disc as compared to anterior cervical discectomy (ACDF), the standard surgical treatment.

    The artificial disc has been used in Europe for a number of years with clinical results that were included as part of the investigational application for the Mobi-C® clinical study in the United States. UC Davis Health System is currently the only Northern California institution conducting this clinical study.