UC Davis Retinal Reading Center
The UC Davis Retinal Reading Center provide comprehensive services for interpreting and analyzing data or images from visual fields (VF), optical coherence tomography (OCT), digital fundus photographs (FP), fluorescein angiography (FA), infrared reflective (IR), fundus autofluorescence (FAF), quantitative autofluorescence (qAF), and OCT angiography (OCT-A). Our services support clinical research in various sectors of ophthalmology including retina, glaucoma, cornea, and neuro-ophthalmic studies; as well as neurology studies. Our reading center ensures rigorous quality control, use of validated and reproducible measures, secure data storage and transfer, as well as training, certification, and feedback for ophthalmic photographers and technicians. The co-directors of the VF/OCT Reading Centers are Drs. John Keltner and Jack Werner. Dr. Yiu is the co-director of retinal programs.
Notable studies include:
- Ocular Hypertension Treatment Study (OHTS) - The largest glaucoma clinical trial to date that evaluated ocular hypertension and open-angle glaucoma progression in 1636 individuals, with nearly 70,000 visual fields analyzed.
- Optic Neuritis Treatment Trial (ONTT) - This randomized study of 448 patients assessed the role of oral steroids and neuroimaging in the management of optic neuritis. Since 1988, UC Davis has served as the reading center for the 15-year follow-up to this trial and evaluated 18,000 visual fields.
Active studies include:
- Analysis of OCT images from the randomized, open-label study comparing intravitreal ranibizumab regimens for treatment of retinal vein occlusions with macular edema.
- Evaluation of choroidal and suprachoroidal changes in a phase II randomized trial of suprachoroidal triamcinolone and intravitreal aflibercept for macular edema from retinal vein occlusions.
- Measurement of geographic atrophy area in a randomized trial for an oral medication for treatment of end-stage nonexudative age-related macular degeneration.