Ralph Green, M.D., Ph.D., F.R.C. PATH
Pathology and Laboratory Medicine
Pathology - Clinical
Pathology - Hematopathology
Philosophy of Care
Dr. Green is consulted by patients and physicians on problems relating to vitamin B12 deficiency including pernicious anemia.
Dr. Green is a recognized expert in the diagnosis of Hematological Disorders, with special emphasis on anemias.
Dr. Green is a recognized expert in the diagnosis and treatment of Nutritional deficiency diseases and disorders.
Dr. Green is the Director of the UC Davis Diagnostics, an outreach reference laboratory that performs clinical laboratory tests.
Dr. Ralph Green has dedicated a major portion of his professional effort to the practice of hematology. He has served on NIH study sections and as a consultant to the World Health Organization, the Food and Drug Administration and the National Academy of Sciences, Institute of Medicine.
He has authored or co-authored over 250 publications. Dr Green serves on the editorial boards of several hematology journals.
He has been a consultant for several biotechnology and biopharmaceutical companies. He has recently served as an expert consultant for the NIH Biomarkers of Nutrition for Development group and the NHLBI Working Group on the Microbiome.
M.D., University of Witwatersrand, Johannesburg, South Africa 1964
Ph.D., Hematology/Biochemistry, University of Witwatersrand, Johannesburg, South Africa 1976
Pathology, University of Witwatersrand, Johannesburg, South Africa 1970-1972
Biochemistry, St. Bartholomew’s Hospital & Medical College, London, England 1967-1969
American Board of Pathology, 1995
Royal College of Pathologists (UK), 2002
American Association for Advancement in Science
American Society for Clinical Nutrition
American Society of Clinical Pathology
American Society of Hematology
College of American Pathologists
International Society for Experimental Hematology
International Society for Laboratory Hematology
Western Association of Physicians
Honors and Awards
Berend Houwen Award and lectureship of the International Society of Laboratory Hematology, 2017
Dean’s Award for Excellence in Clinical Care, 2014
Special Award from APC Program Directors for Extraordinary Service to Pathology Resident Education, 2010
American Registry of Pathologists AFIP/Calendar Binford Lecturer Washington, DC, 2006
Royal College of Pathologists, 2002
Opening of Singapore Postgraduate Medical Institute (Keynote Speaker), 1995
Select Recent Publications
Christine CW, Auinger P, Joslin A, Yelpaala Y, Green R; Parkinson Study Group-DATATOP Investigators. Vitamin B12 and homocysteine levels predict different outcomes in early Parkinson's disease. Mov Disord. 2018 Mar 6.
Green R. Vitamin B(12) deficiency from the perspective of a practicing hematologist. Blood. 2017 May 11;129(19):2603-2611.
Green R, Allen LH, Bjørke-Monsen AL, Brito A, Guéant JL, Miller JW, Molloy AM, Nexo E, Stabler S, Toh BH, Ueland PM, Yajnik C. Vitamin B(12) deficiency. Nat Rev Dis Primers. 2017 Jun 29;3:17040.
Paniz C, Bertinato JF, Lucena MR, De Carli E, Amorim PMDS, Gomes GW, Palchetti CZ, Figueiredo MS, Pfeiffer CM, Fazili Z, Green R, Guerra-Shinohara EM. A Daily Dose of 5 mg Folic Acid for 90 Days Is Associated with Increased Serum Unmetabolized Folic Acid and Reduced Natural Killer Cell Cytotoxicity in Healthy Brazilian Adults. J Nutr. 2017 Sep;147(9):1677-1685.
Brito A, Grapov D, Fahrmann J, Harvey D, Green R, Miller JW, Fedosov SN, Shahab-Ferdows S, Hampel D, Pedersen TL, Fiehn O, Newman JW, Uauy R, Allen LH. The Human Serum Metabolome of Vitamin B-12 Deficiency and Repletion, and Associations with Neurological Function in Elderly Adults. J Nutr. 2017 Aug 9. pii: jn248278.
Engle-Stone R, Williams TN, Nankap M, Ndjebayi A, Gimou MM, Oyono Y, Tarini A, Brown KH, Green R. Prevalence of Inherited Hemoglobin Disorders and Relationships with Anemia and Micronutrient Status among Children in Yaoundé and Douala, Cameroon. Nutrients. 2017 Jul 3;9(7). pii: E693.
Green R. Peripheral neuropathy risk and a transcobalamin polymorphism: connecting the dots between excessive folate intake and disease susceptibility. Am J Clin Nutr. 2016 Nov 16;104(6):1495-6.
Brito A, Verdugo R, Hertrampf E, Miller JW, Green R, Fedosov SN, Shahab-Ferdows S, Sanchez H, Albala C, Castillo JL, Matamala JM, Uauy R, Allen LH. Vitamin B-12 treatment of asymptomatic, deficient, elderly Chileans improves conductivity in myelinated peripheral nerves, but high serum folate impairs vitamin B-12 status response assessed by the combined indicator of vitamin B-12 status. Am J Clin Nutr. 2016 Jan;103(1):250-7.
Green R, Dwyre DM. Evaluation of Macrocytic Anemias. Semin Hematol. 2015 Oct;52(4):279-86. Epub 2015 Jun 30. Review.
Nathanielsz PW, Yan J, Green R, Nijland M, Miller JW, Wu G, McDonald TJ, Caudill MA. Maternal obesity disrupts the methionine cycle in baboon pregnancy. Physiol Rep. 2015 Nov;3(11).