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July 2016arrow

De Vere White to serve on prestigious NIH panel

July 26, 2016

Ralph de Vere White, who retired in June as director of the UC Davis Comprehensive Cancer Center, has been named to a key committee at the National Institute of Health (NIH).

UC Davis scientists awarded grant for rare genetic disorder research

July 21, 2016

The state stem cell agency, the California Institute for Regenerative Medicine (CIRM), today approved a $1.1 million grant to UC Davis for research aimed at developing a treatment for Angelman syndrome,  a rare, neurogenetic autism-spectrum disorder that occurs in one in 15,000 live births.

UC Davis researchers temporarily turn off brain area to better understand function

July 20, 2016

Capitalizing on experimental genetic techniques, researchers at UC Davis’ California National Primate Research Center (CNPRC) have demonstrated that temporarily turning off an area of the brain changes patterns of activity across much of the remaining brain.

High quality MRIs without sedation are possible in severely affected children with autism

July 19, 2016

UC Davis researchers have found a way to get MRI images of children with autism spectrum disorder (ASD) and intellectual disability without sedating them first using the principles of applied behavior analysis.

Historic data to aid in long-term study of ethnic disparities in brain health and dementia

July 14, 2016

Physical exams conducted from the 1960s through the 1980s will be revisited to evaluate risks and protective factors in early and midlife that could affect brain health and dementia diagnoses among a large, ethnically diverse group of seniors. The Kaiser Permanente Northern California Division of Research will partner with the UC Davis Alzheimer’s Disease Center for the study, which is funded with a five-year, $13 million grant from the National Institute on Aging.

Oncologists and cancer patients often differ in prognosis perceptions

July 14, 2016

Patients with stage III or IV cancer report far more optimistic expectations for survival than their oncologists thought they had communicated, according to new research published today in JAMA Oncology. Effective communication between doctors and their patients who could be nearing the end of their lives is crucial, according to the authors, since this is when quality-of-life decisions merge with discussions about treatment options.

New grant further solidifies UC Davis' leadership role in translational research

July 12, 2016

The UC Davis Clinical and Translational Science Center (CTSC) and the wide array of services that have supported innovative biomedical research and led to the development of new treatments for diseases during the past 10 years will continue, thanks to a $27.8 million grant from the National Center for Accelerating Translational Science and the ongoing support from the School of Medicine.

UC Davis scientists awarded grant for rare genetic disorder research

July 5, 2016

The London-based LouLou Foundation, in partnership with the Orphan Disease Center of the Perelman School of Medicine at the University of Pennsylvania, has awarded a grant to UC Davis Institute for Regenerative Cures Director Jan Nolta and one of the institute’s post-doctoral fellows, Kyle Fink, to study how Fink’s gene editing techniques might be used to treat a rare genetic disorder that hits children – mainly girls – at a very young age with difficult-to-control seizures and severe neuro-developmental impairment.

June 2016arrow

Beware of unapproved stem cell procedures

June 30, 2016

At least 351 companies across the United States are marketing unapproved stem cell procedures, according to a new study by a UC Davis stem cell researcher and a University of Minnesota bioethicist.

Study shows that some, but not all, premenstrual symptoms are linked with inflammation

June 23, 2016

Certain premenstrual symptoms, such as mood changes, breast pain and abdominal cramps, are linked with inflammation, but headache is not, according to new research from UC Davis Health System. Published in the current issue of the Journal of Women’s Health, the results suggest that anti-inflammatory medications may be appropriate for some but not all symptoms associated with menstruation.

"Digital neurotherapeutic" in development at the UC Davis MIND Institute

June 22, 2016

A UC Davis researcher has created a video game for children who experience cognitive impairments from genetic disorders with the hope that that it will improve their ability to mentally process information about space and time.

Nearly 10 million U.S. adults severely nearsighted

June 22, 2016

A new study by investigators at the American Academy of Ophthalmology, Genentech, the National Institutes of Health and UC Davis Eye Center has found that 9.6 million U.S. adults are highly myopic, or severely nearsighted, and of those, nearly 820,000 have a degenerative form of the disease and more than 41,000 suffer myopic choroidal neovascularization, a complication that can cause long-term vision loss, especially in women.

MIND Institute researcher studies feasibility of community providers training parents of children with autism

June 22, 2016

Research has long shown that parent-implemented “naturalistic developmental behavioral interventions,” which are applied in a child’s usual setting and designed to build developmentally appropriate skills, help decrease the main symptoms of autism spectrum disorder (ASD). However, parent training by community providers had not previously been studied.

Mothers with diabetes, other metabolic conditions, more likely to also have anti-fetal brain autoantibodies

June 17, 2016

Mothers of children with autism who were diagnosed with metabolic conditions during pregnancy, particularly gestational and type 2 diabetes, were more likely to have anti-fetal brain autoantibodies in their blood compared to healthy women of children with autism. The presence of these anti-fetal brain autoantibodies has been previously found to be specific to some mothers of children with autism and rare among mothers of children without autism, researchers with the UC Davis MIND Institute have found.

UC Davis study finds antibiotics increase availability of nutrients in the gut, enabling growth of pathogens

June 15, 2016

Research led by Andreas Bäumler, professor of medical immunology and microbiology at UC Davis Health System, has identified a new mechanism explaining how antibiotics change the gut microbiota, increasing nutrients that benefit the growth of pathogens, like Salmonella.

UC Davis establishes research center to tackle pain epidemic

June 13, 2016

Leveraging the vast expertise of scholars and scientists in medicine, nursing and other health science disciplines, UC Davis has established the Center for Advancing Pain Relief.

NIH funding for dermatology research trending downward for women and MDs

June 9, 2016

In a retrospective study of dermatology research awards from the National Institutes of Health (NIH) from 2009 to 2014, a team of UC Davis researchers found a significant decline in women investigators and a striking reduction in MD-only investigator funding dollars.

Risk of autism with intellectual disability linked with maternal immune dysfunction during pregnancy

June 7, 2016

Pregnant women with higher levels of inflammatory cytokines and chemokines, proteins that control communication between cells of the immune system, may be at significantly greater risk of having a child with autism combined with intellectual disability, researchers with the UC Davis MIND Institute have found.

Lung cancer patients who have surgery live longer

June 7, 2016

Patients with late-stage, non-small cell lung cancer (NSCLC) who have surgery have better survival rates than those who don’t, but fewer of these patients are undergoing surgery, UC Davis researchers have found.

May 2016arrow

MIND Institute study examines development of school-age children with autism spectrum disorder

May 27, 2016

Grade school is an important period in children’s development, when they begin to mature and prepare to enter adolescence. Now, researchers with the UC Davis MIND Institute hope to discover how to maximize that growth among children with autism to help them learn and thrive.

Inhaled silver particles end up in the brain, UC Davis study shows

May 26, 2016

Airborne silver nanoparticles that are common in occupational settings travel from the nose to the brain, where they can remain for weeks and trigger an immune response linked with injury, UC Davis researchers studying adult rats have found.

Miglioretti awarded $7.5 million to evaluate supplemental breast imaging

May 25, 2016

Diana Miglioretti, UC Davis dean’s professor of biostatistics and an internationally recognized breast cancer screening expert, has received $7.5 million to determine the effectiveness of two supplemental breast screening and diagnostic workup strategies -- digital breast tomosynthesis (3D mammography) and magnetic resonance imaging (MRI) -- used with mammography for cancer detection. Miglioretti’s team also will work to determine whether effectiveness of the screening strategies depends on a woman’s breast density.

UC Davis Alzheimer's Disease Center establishes new Cognitive Neurosciences Fellowship

May 25, 2016

The UC Davis Alzheimer’s Disease Center has established a new, integrated translational cognitive neuroscience postdoctoral fellowship program through a five-year, $1 million grant from the National Institute on Aging.

Calcium channels team up to activate excitable cells

May 18, 2016

Voltage-gated calcium channels open in unison, rather than independently, to allow calcium ions into and activate excitable cells such as neurons and muscle cells, researchers with UC Davis Health System and the University of Washington have found.

Physicians can counsel patients to prevent gun violence, experts say

May 17, 2016

It is not illegal for physicians to ask their patients about firearms, counsel them as they would on any other health matter, and disclose that information to third parties when necessary, according to a review of the literature by physicians at UC Davis, Brown University, and the University of Colorado who are helping to lead the effort to prevent firearm-related injuries in the U.S.

UC Davis researchers identify new metabolic disorder

May 12, 2016

Researchers at UC Davis have identified a new metabolic disorder that affects newborns and leads to death hours after their birth. Identification of the genetic defect has meant the delivery of a healthy newborn to a mother who earlier had lost two other newborns to the condition.

More research needed to identify and measure quality of autism interventions

May 10, 2016

With the dramatic rise of children diagnosed with autism spectrum disorder (ASD), the numbers and types of interventions promoted to families and individuals with autism have surged as well.

Device worn on eyeglasses offers hope for people with low vision

May 5, 2016

A miniature camera using optical character-recognition technology, mounted onto the eyeglasses of people who are considered legally blind, dramatically improves their ability to read an email, newspaper article, menu or page in a book, a study by researchers with UC Davis Health System.

UC Davis teams receive prestigious CITRIS awards for innovation in human health

May 4, 2016

Three UC Davis Health System teams have been selected from among 54 highly competitive proposals to receive awards to develop innovative information technology solutions in human health care from the Center for Information Technology Research in the Interest of Society — CITRIS — a collaboration of the UC campuses at Berkeley, Davis, Merced and Santa Cruz. The grants are awarded in collaboration with the Banatao Institute founded by high-tech entrepreneur and philanthropist Dado Banatao.  

Autism and cancer share a remarkable number of risk genes in common

May 3, 2016

Autism and cancer share more than 40 risk genes, suggesting that common mechanisms underlying the functions of some of these genes could conceivably be leveraged to develop therapies not just for cancer but for autism as well, an extensive assessment by researchers with the UC Davis MIND Institute and Comprehensive Cancer Center has found.

Antibiotics allow gut pathogens to breathe

May 2, 2016

Antibiotics are essential for fighting bacterial infection, but, paradoxically, they can also make the body more prone to infection and diarrhea. Research led by Andreas Bäumler, professor of medical immunology and microbiology at UC Davis Health System, has identified the chain of events that occur within the gut lumen after antibiotic treatment that allow “bad” bugs to flourish.

Common supplement boosts kidney cancer therapy

May 2, 2016

Researchers at UC Davis have shown that docosahexaenoic acid (DHA), a fatty acid commonly found in fish and fish oil supplements, reduces renal cell carcinoma invasiveness, growth rate, and blood vessel growth when combined with the anti-cancer therapy regorafenib. The study was published in the May issue of the journal Molecular Cancer Therapeutics.

Targeted hepatitis B virus screening effective in addressing infection, liver disease risk

May 2, 2016

A community-based hepatitis B virus screening effort led by UC Davis researchers found that targeted outreach to Asian American populations can identify groups at high risk for infection and direct them to appropriate follow-up care to help prevent the onset of liver diseases, including cancer.