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News from UC Davis Health System

July 2015arrow

UC Davis offers stroke-prevention alternative for patients with atrial fibrillation

July 29, 2015

Cardiologists at UC Davis are the first in Northern California to treat the major risk of stroke that comes with atrial fibrillation (AF), the most common form of arrhythmia, with a device that blocks blood clots from traveling from the heart to the head.

UC Davis trauma center re-verified as level I by the American College of Surgeons

July 28, 2015

The trauma center at UC Davis has been re-verified as level 1 by the American College of Surgeons, making it one of only three trauma centers in California with level I verification in both pediatric and adult trauma care.

Autism costs estimated to reach nearly $500 billion, potentially $1 trillion, by 2025

July 28, 2015

UC Davis health economists have for the first time projected the total costs of caring for all people with autism spectrum disorder (ASD) in the U.S. for the current calendar year and in 10 years if effective interventions and preventive treatments for the condition are not identified and widely available.

UC Davis researchers awarded grant for HIV clinical trial using stem cells

July 23, 2015

The state stem cell agency, the California Institute for Regenerative Medicine (CIRM), today approved funding a UC Davis Health System research team to conduct a clinical trial using bioengineered stem cells to treat HIV patients suffering from lymphoma, one of the deadly conditions associated with the disease.

UC Davis researchers identify the source of the debilitating memory loss in people with psychosis

July 22, 2015

As disabling as its delusions and hallucinations, psychosis’ devastating toll on memory arises from dysfunction of frontal and temporal lobe regions in the brain that rob sufferers of the ability to make associative connections, a UC Davis study has found, pinpointing potential target areas for treatments to help the more than 3.2 million Americans for whom medication quells the voices and visions, but not the struggle to remember. [en español]

One of America's top hospitals

July 21, 2015

UC Davis medical Center has again ranked as one of the best hospitals in the U.S. for 2015-16 in 10 adult medical specialties by U.S. News & World Report.

UC Davis Alzheimer's researchers at core of leading-edge dementia discoveries

July 16, 2015

Imaging the brain, collecting clinical measurements and biological specimens, and generating an unprecedented volume of data for more than 1,700 participants, the groundbreaking Alzheimer's Disease Neuroimaging Initiative (ADNI) has painted a detailed picture of the brain’s progression from cognitive impairment to Alzheimer’s disease, often over many years, demonstrating that while amyloid brain deposits are a leading factor in dementia, there is considerable heterogeneity in cognitive decline in aging.

UC Davis Medical Center awarded 'Most Wired 2015' designation

July 10, 2015

UC Davis Medical Center has again earned “Most Wired” designation as one of the nation’s top health leaders in information technology. The 2015 award is based on a national survey conducted by Hospitals & Health Networks.

New medical school admission process doesn't reduce diversity

July 8, 2015

Under-represented minorities fare as well as others in an increasingly popular method of selecting medical school students known as the Multiple Mini Interview, or MMI, according to new research from the UC Davis School of Medicine.

UC Davis study identifies tools, strategies for enhancing obesity prevention in rural communities

July 7, 2015

Researchers at UC Davis have reviewed a successful telemedicine intervention against pediatric obesity to better understand what worked (or didn’t) and how similar programs can be improved.

June 2015arrow

Level I trauma experience prepares surgeons for battle

June 30, 2015

Soldiers injured during the conflicts in Iraq and Afghanistan have the highest survival rates in history, thanks to the availability of surgeons skilled in combat care.

UC Davis study guides efforts to find new strategies, solutions to fight pediatric asthma

June 26, 2015

Low flu vaccination rates, medication compliance and limited access to primary care providers have contributed to poor outcomes for pediatric asthma in California, say UC Davis pediatricians Ulfat Shaikh and Robert Byrd, who have published an extensive study describing the challenges faced by children with asthma in California. [en español]

The constant movement in ADHD may help children think, perform in school

June 10, 2015

The constant movement of children with attention-deficit/hyperactivity disorder (ADHD) may be distracting -- but the fidgeting also may improve their cognitive performance, a study by researchers with the UC Davis MIND Institute has found. The take-away message: The hyperactivity seen in ADHD may help children think. [en español]

UC Davis Children's Hospital listed in the nation's Best Children's Hospital rankings

June 9, 2015

UC Davis Children’s Hospital has been ranked by U.S. News & World Report among the nation’s top hospitals in five pediatric subspecialties. Together with Shriners Hospital for Children – Northern California, its longstanding partner in caring for children with burns, spinal cord injuries, urological issues and orthopaedic disorders, UC Davis Children's Hospital ranked 29th in orthopaedics and 20th in urology. UC Davis also ranked 17th in neonatology, 33rd in diabetes and endocrinology and 45th in neurology and neurosurgery. 

Early intervention program improves long-term outcomes for children with autism

June 9, 2015

An early intervention program for toddlers with autism spectrum disorder improves their intellectual abilities and reduces autism symptoms -- and those results persist years after the children originally received treatment, a new study shows.

Body's response to spicy foods guides design of new pain relief drugs

June 9, 2015

UC Davis researchers have identified the molecular interactions that allow capsaicin to activate the body’s primary receptor for sensing heat and pain, paving the way for the design of more selective and effective drugs to relieve pain. Their work appeared online June 8 in the journal Nature Chemical Biology.

May 2015arrow

Restricting firearms access for people who misuse alcohol may prevent violence

May 28, 2015

Restricting access to firearms for people who misuse alcohol could prevent firearm violence, but policies that more clearly define alcohol misuse should be developed to facilitate enforcement, according to a review of existing research and public policies by the UC Davis Violence Prevention Research Program.

Results for microbes collected by citizen scientists and grown on the International Space Station

May 27, 2015

Do microbes grow differently on the International Space Station than they do on Earth? Results from the growth of microbes collected by citizen scientists in Project MERCCURI indicate that most behave similarly in both places.

Common heart disease medication could help asthmatics too

May 26, 2015

A drug prescribed to prevent or stall the progress of heart disease may also relieve symptoms of asthma, according to a new study from pulmonary medicine specialists at UC Davis Health System.

UC Davis study finds significant cost savings in pediatric telemedicine consults compared to phone consults

May 21, 2015

Researchers at UC Davis have conducted a comprehensive study to determine whether pediatric telemedicine consultations with rural emergency departments save money compared to telephone consults. The answer is a resounding yes. While telemedicine systems are expensive to install and maintain, they more than pay their way, saving an average $4,662 per use. The study was published in the journal Medical Decision Making. [en español]

UC Davis Medical Center rated among the nation's high performing hospitals by U.S. News & World Report

May 20, 2015

New U.S. News & World Report hospital ratings for five common procedures and conditions show that UC Davis Medical Center is a “high performer” for heart bypass surgery, hip replacements, heart failure and chronic obstructive pulmonary disease (COPD), and meets expected standards of care for knee replacements.

Osteoporosis screening is too common for low-risk women and too uncommon for higher-risk women

May 19, 2015

Many of those who should get it, don’t. And many of those who shouldn’t, do. That’s the story of a common screening test for osteoporosis, according to new research from UC Davis Health System.

Revealing kidney cancer's secret

May 14, 2015

An international team of scientists, led by UC Davis nephrologist Robert Weiss, have used a sophisticated combination of proteomics and metabolomics to show how renal cell carcinoma (RCC) reprograms its metabolism and evades the immune system. In addition, the study found that cancer grade has a major impact on this reprogramming. These results, published in the journal Cancer Research, point to new therapeutic options for this particularly deadly cancer.

UC Davis tests deep brain stimulation as a treatment for cognitive changes in Parkinson's

May 12, 2015

Surgeons at UC Davis Health System are testing an innovative method of limiting cognitive decline in patients with Parkinson’s disease. The treatment — deep brain stimulation, or DBS — involves delivering low levels of electrical stimulation to a part of the brain that controls the abilities to think, plan and remember.

UC Davis MIND Institute research finds differences in the brains and behavior of girls and boys with autism

May 12, 2015

New research conducted by the UC Davis MIND Institute on a large cohort of preschoolers with autism spectrum disorder has found differences in the underlying biology of their brains, and in  their behavior, that may help explain how the condition affects a little-studied and poorly understood population of children: girls. [en español]

New UC Davis program targets next generation of physicians to advance Latino health

May 4, 2015

The University of California, Davis and The Permanente Medical Group today launched a new initiative at UC Davis School of Medicine dedicated to building the next generation of physicians committed to advancing Latino health. [en español]

April 2015arrow

UC Davis Medical Center receives 'A' for patient safety from Leapfrog for fourth consecutive reporting period

April 30, 2015

The Leapfrog Group, a non-profit coalition of some of the country’s largest employers and health-care purchasers, has again awarded UC Davis Medical Center the highest grade possible, an “A,” on its most recent Hospital Safety Score, an evaluation that ranks hospitals nationwide on the likelihood that its patients will be free from preventable harm during their inpatient stays. This marks the fourth reporting period in a row that UC Davis has achieved the distinction.

NCI funding boosts breast CT scanning research and development

April 29, 2015

John M. Boone, a UC Davis medical physicist and professor of radiology, has been awarded a $2.88 million grant from the National Cancer Institute to further develop and research computed tomography (CT) to detect breast cancer.

Higher BMI associated with reduced costs, better health for diabetics

April 28, 2015

It’s a paradox: Diabetics with above-normal weight use health care less and report overall better physical health than their diabetic counterparts with normal weight, according to two new studies from UC Davis Health System.

UC Davis makes breakthrough in understanding Canavan disease

April 27, 2015

UC Davis investigators have settled a long-standing controversy surrounding the molecular basis of an inherited disorder that historically affected Ashkenazi Jews from Eastern Europe but now also arises in other populations of Semitic descent, particularly families from Saudi Arabia.

Prenatal stem cell treatment improves mobility issues caused by spina bifida

April 24, 2015

The lower-limb paralysis associated with spina bifida may be effectively treated before birth by combining a unique stem cell therapy with surgery, new research from UC Davis Health System has found.

Rare mutation causes vitamin A deficiency and eye deformities

April 23, 2015

Researchers at the University of Michigan and UC Davis have solved a genetic mystery that has afflicted three unrelated families, and possibly others, for generations. These families have been plagued by a variety of congenital eye malformations, including small eyes with poor vision and the complete absence of eyes. But until now, no one could figure out the genetic basis for these conditions. [en español]

MIND Institute researchers receive grant to study schizophrenia in children with 22q11.2 deletion syndrome

April 21, 2015

Researchers studying a genetic disorder that in childhood causes anxiety and learning differences, but in adolescence or early adulthood results in schizophrenia in nearly one third of those affected, will investigate how emotional and intellectual challenges impact the development of early psychosis symptoms in this very high-risk population, through a new five-year, $2.5 million grant from the National Institute of Mental Health.

UC Davis Medical Center named one of 100 Great Hospitals in America

April 21, 2015

Becker’s Hospital Review has named UC Davis Medical Center to its 2015 list of 100 Great Hospitals in America.

More work is needed to find the causes of flu vaccine disparities for the elderly

April 20, 2015

Public health specialists need to look beyond traditional solutions — such as expanding access to health insurance and primary care — to increase flu vaccination rates among older African Americans and Hispanics, according to a new study from UC Davis Health System and UCLA Health System.

UC Davis Alzheimer's Disease Center opens new clinic in Walnut Creek

April 16, 2015

The UC Davis Alzheimer's Disease Center, one of only 27 research centers designated by the National Institutes of Health's National Institute on Aging, has established a new clinic in the East Bay in Walnut Creek.

UC Davis researchers win grant to answer key questions in surveillance of small lung nodules

April 15, 2015

Two UC Davis researchers will help run a major national study to improve surveillance practices for patients with small lung nodules identified on CT imaging and extremely low risk for lung cancer.

Freischlag part of White House roundtable on climate change and health

April 10, 2015

Julie Freischlag, dean of the UC Davis School of Medicine, yesterday participated in a roundtable discussion at the White House on educating tomorrow’s health leaders about the impacts of climate change on human health.

Founding dean of UC Davis nursing school named among top Sacramento business women

April 10, 2015

Heather M. Young, the founding dean of the Betty Irene Moore School of Nursing at UC Davis, was today named one of the Sacramento Business Journal’s “2015 Women Who Mean Business.”

A mother's genes can influence the bacteria in her baby's gut, researchers at UC Davis have found

April 9, 2015

Researchers at UC Davis have found that a gene, which is not active in some mothers, produces a breast milk sugar that influences the development of the community of gut bacteria in thier infants. The sugars produced by these mothers, called "secretors," are not digested by the infant, but instead nourish specific bacteria that colonize their babies' guts soon after birth.

Women, regardless of their backgrounds, seek help for the 'got to go' feeling

April 7, 2015

 Regardless of their racial, ethnic, educational or socioeconomic background, women seek help for a frustrating — and ubiquitous — feature of becoming "a woman of a certain age:" the need be close to the women's room.

Study finds characteristic pattern of protein deposits in retired NFL players' brains

April 7, 2015

A brain-imaging technique may enable the early detection of chronic traumatic encephalopathy (CTE), according to a study published in the Proceedings of the National Academy of Sciences.

No-cost mapping services available for California-based labs to meet Meaningful Use requirements

April 6, 2015

As part of national Meaningful Use initiative, which aims to improve the coordination of care and electronic exchange of patient information among hospitals, labs, physicians and other health care organizations, providers must be able to receive and incorporate structured lab results from clinical laboratories using universal code systems for identifying laboratory and clinical observations, specifically LOINC (Logical Observation Identifiers Names and Codes) and SNOMED CT (Systematized Nomenclature of Medicine Clinical Terms).

$2.5 million Dignity Health gift to UC Davis nursing school creates first endowed deanship

April 3, 2015

The Betty Irene Moore School of Nursing at UC Davis announced today it received a $2.5 million gift from Dignity Health to create the first endowed deanship at UC Davis.

Small RNA plays big role suppressing cancer

April 2, 2015

The micro RNA miR-22 has long been known for its ability to suppress cancer. However, questions remain about how it achieves this feat. For example, which molecules are regulating miR-22, and which are miR22 targets?

UC Davis neuroscientist recognized for color vision and aging contributions

April 1, 2015

John S. Werner, a UC Davis neuroscientist and international authority on visual perception, has been selected to receive the 2015 Verriest Medal from the International Colour Vision Society for his contributions to understanding the structural and functional basis of color vision, how and why vision changes across the life span, and factors that contribute to loss of vision associated with disease. He will receive the award at the society’s biennial symposium in Sendai, Japan, on July 4. 

March 2015arrow

International team of researchers led by UC Davis receives $4 million NIH grant to study skull disorder in infants

March 31, 2015

Simeon Boyd, UC Davis professor of genetics and pediatrics, has received a nearly $4 million, five-year grant from the National Institute of Dental and Craniofacial Research to lead a team of physicians and scientists from more than 10 centers in the United States and seven international sites, including Australia, Brazil, Bulgaria, Germany, Hungary, Italy and the United Kingdom, to study craniosynostosis, the premature fusion of the bony plates of the skull in infants.

Protein may improve liver regeneration

March 31, 2015

Researchers at UC Davis have illuminated an important distinction between mice and humans: how human livers heal. The difference centers on a protein called PPARα, which activates liver regeneration. Normally, mouse PPARα is far more active and efficient than the human form, allowing mice to quickly regenerate damaged livers. However, the research shows that protein fibroblast growth factor 21 (FGF21) can boost the regenerative effects of human PPARα.

UC Davis receives stem cell grants for novel spina bifida and diabetic wound treatments

March 26, 2015

The state stem cell agency, California Institute for Regenerative Medicine (CIRM), today awarded a pair of grants totaling more than $7 million to UC Davis School of Medicine researchers who are working to develop stem cell therapies for spina bifida and chronic diabetic wounds.

UC Davis receives $10 million grant to establish center to study schizophrenia

March 26, 2015

UC Davis will establish a prestigious, leading-edge center to advance innovative research into the origins of schizophrenia: A Silvio O. Conte Center for Basic or Translational Mental-Health Research, one of only 15 such centers in the United States.

Emergency medicine physicians urge colleagues to help prevent gun violence

March 25, 2015

In an editorial posted online today in the Annals of Emergency Medicine, two practicing emergency medicine physicians from the University of California, Davis, and Brown University — both thought leaders at the forefront of finding solutions to the public health crisis of gun violence — urge their colleagues to take direct action to protect the health and safety of patients and communities.

Firearm violence trends in the 21st century

March 19, 2015

While the overall death rate from firearm violence has remained unchanged for more than a decade, the patterns for suicide and homicide have changed dramatically, a UC Davis study on the epidemiology of gun violence from 2003 to 2012 has found. The study was published today in the Annual Review of Public Health.

Randi Hagerman receives International Sisley-Lejeune Foundation Award

March 18, 2015

Randi Hagerman, medical director of the UC Davis MIND Institute, has received the prestigious International Sisley-Jerome Lejeune Award 2014 from the Paris-based Jérôme Lejeune Foundation, for her groundbreaking work developing targeted treatments for individuals with fragile X syndrome, a leading cause of intellectual disability and the leading single-gene cause of autism spectrum disorder.  

Commentary says study affirms that varied factors contribute to cognitive decline throughout adulthood

March 16, 2015

A study published online today in JAMA Neurology that finds associations between reduced hippocampal volume (HVa) and being male, but not the gene APOE ɛ4, suggests that there are multiple factors contributing to cognitive decline throughout adulthood, according to an accompanying commentary by UC Davis Alzheimer's Disease Center Director Charles DeCarli.

U.S. News & World Report ranks new UC Davis School of Nursing among best

March 10, 2015

For the first time, U.S. News & World Report ranks the Betty Irene Moore School of Nursing at UC Davis as among the best in the country for master’s-degree nursing programs in the 2016 U.S. News & World Report Best Graduate Schools.

UC Davis School of Medicine ranks among nation's best in primary care, research

March 10, 2015

U.S. News & World Report has ranked UC Davis School of Medicine among America's best medical schools for the quality of its educational programs in primary care and research. The news magazine's annual listing appeared today on the publication's website and will be published in its guidebook “Best Graduate Schools 2016.”

Lim receives Kun-Po Soo Award from American Psychiatric Foundation

March 6, 2015

Russell Lim, director of Diversity Education and Training for the UC Davis Department of Psychiatry and Behavioral Sciences, has received the 2015 Kun-Po Soo Award from the American Psychiatric Foundation, for his contributions to understanding the importance of addressing culture in mental-health issues.

Darrell Steinberg joins UC Davis Behavioral Health Center of Excellence

March 4, 2015

Darrell Steinberg, former Senate pro tempore for the state of California, has joined the faculty of the UC Davis School of Medicine as director of policy and advocacy for the recently launched UC Davis Behavioral Health Center of Excellence.

UC Davis scientists describe novel drug mechanism that fights brain cancer

March 3, 2015

Researchers at UC Davis have developed and characterized a molecule that interferes with the internal regulation of cancer cells, causing them to self-destruct. This novel mechanism was found to be effective against glioma cells – responsible for a usually fatal type of brain cancer – and could be applicable to other highly aggressive cancers.

February 2015arrow

UC Davis Huntington's Disease Center receives Level 1 designation

February 27, 2015

The UC Davis Huntington’s Disease Center, whose compassionate patient care and research expertise have made it a beacon of hope for people with Huntington’s disease throughout Northern California and beyond, has been acknowledged by the national society committed to the values that it so ably upholds  the Huntington’s Disease Society of America — as a Level 1 Huntington’s Disease Center of Excellence.

Welltopia: A new online resource for Californians

February 25, 2015

Welltopia, a new website launched today by the California Department of Health Care Services (DHCS) and the UC Davis Institute for Population Health Improvement (IPHI), offers a wide range of essential resources to help Californians, especially those on limited incomes, build healthier lives and communities.

Undocumented farmworkers use Medicaid half as often as documented farmworkers

February 23, 2015

Undocumented farmworkers are half as likely as those who are documented to use Medicaid, the federal health insurance program available to low-income individuals and families, according to a new study from UC Davis Health System.

Hispanics develop alcoholic liver disease at younger ages than Caucasians or African Americans

February 20, 2015

Hispanics tend to develop alcoholic liver disease (ALD) — a common cause of liver-disease deaths in the U.S. — between four and 12 years earlier than non-Hispanic Caucasians or African Americans, according to a UC Davis Health System study.

UC Davis Center for Pain Medicine named Clinical Center of Excellence

February 18, 2015

The American Pain Society has selected the UC Davis Center for Pain Medicine as a 2015 Clinical Center of Excellence. 

Kizer selected for expert panel to assess U.S. Census Bureau

February 17, 2015

Kenneth W. Kizer, distinguished professor and director of the Institute for Population Health Improvement, has been chosen by the National Academy of Public Administration (NAPA) to sit on a five-member panel of management experts convened to evaluate the planned restructuring of the national Bureau of the Census. The evaluation is directed by the Appropriations Committee of the U.S. House of Representatives.

UC Davis designated a Lung Cancer Screening Center

February 11, 2015

UC Davis Health System has been endorsed by the American College of Radiology as a designated lung cancer screening center, the only of its kind currently in the greater Sacramento area.

UC Davis researchers identify new compound that takes aim at neuropathic pain

February 10, 2015

A new compound discovered by a team of UC Davis investigators has potent actions against production of a chemical that is implicated in the development of chronic pain following a peripheral nerve injury in the spinal cord.

A simple information sheet can help women avoid pregnancy and acne medication-related birth defects

February 4, 2015

An information sheet for women being treated for severe acne improves understanding of contraceptive effectiveness and ways to avoid pregnancy and medication-induced birth defects, a study published today in JAMA Dermatology has found.

Nerve regeneration therapy has potential to prevent arrhythmias, sudden cardiac death after heart attack

February 2, 2015

A therapy currently under development for spinal cord injuries has been shown to stimulate nerve regeneration in the heart and provide resistance to arrhythmias following a heart attack, according to a new study published today in the journal Nature Communications.

UC Davis scientists awarded nearly $4 million for technology in vascular disease treatment and bone and cartilage repair

February 2, 2015

The California Institute for Regenerative Medicine (CIRM) has awarded a pair of $1.8 million grants to two UC Davis scientists to develop better tools for enabling physicians to assess the safety and efficacy of bioengineered tissues used to treat cardiovascular disease and bone and cartilage repair.

January 2015arrow

California Department of Public Health, Sacramento County Department of Health and Human Services and UC Davis Medical Center - Sacramento Confirm Patient at Hospital has Tested Negative for Ebola

January 30, 2015

State and local public health and hospital officials have confirmed that the patient transported by specialized ambulance and admitted to UC Davis Medical Center early Thursday who exhibited symptoms consistent with a viral illness including Ebola, and with a history of travel to an Ebola-affected country, has tested negative for the Ebola virus.

California breast density law slow to have an impact

January 28, 2015

Ten months after California legislators enacted a controversial law mandating that radiologists notify women if they have dense breast tissue, UC Davis researchers have found that half of primary care physicians are still unfamiliar with the law and many don’t feel comfortable answering breast density-related questions from patients.

Project ADAM's first California affiliate established at UC Davis Children's Hospital

January 21, 2015

A life-saving program that helps to prevent sudden cardiac arrest in children and teens has now arrived in California. UC Davis Children’s Hospital has become the first California affiliate for Project ADAM (Automated Defibrillators in Adam’s Memory), a non-profit organization dedicated to establishing comprehensive defibrillation programs in schools across the country.

Trauma surgery moves outside of the OR, fills gaps across specialties

January 20, 2015

Historically known as heroes who put people back together after accidents, trauma surgeons today perform a broad array of surgical procedures, are involved in planning patient care and treat patients at hospital bedsides in addition to operating rooms, a UC Davis Health System study has found.

Treating non-healing bone fractures with stem cells

January 15, 2015

A new device that can rapidly concentrate and extract young cells from irrigation fluid used during orthopaedic surgery holds promise for improving the delivery of stem cell therapy in cases of non-healing fractures.

UC Davis emergency medicine physician recognized for gun violence prevention work

January 13, 2015

Garen J. Wintemute, one of the nation’s foremost scholars addressing gun violence as a public-health problem, will receive the Distinguished Alumni Award from the California Aggie Alumni Association for his exemplary professional achievements and service.

Aubyn Stahmer, expert in translating autism research into community practice, joins UC Davis MIND Institute

January 8, 2015

Aubyn Stahmer, an expert in the translation of evidence-based autism research to community-based practice and delivery, has joined the UC Davis MIND Institute as an associate professor in the Department of Psychiatry and Behavioral Sciences.

Study identifies patients at higher risk for overdose and death from prescription painkillers

January 7, 2015

Patients started on prescription painkillers who have substance-use disorders or who frequently contact their doctors’ offices are at greater risk of having their medication doses increase early in therapy, also increasing their risk of opioid-related overdose or death, UC Davis Health System researchers have found.

December 2014arrow

New technique for bioengineering stem cells shows promise in HIV resistance

December 22, 2014

Using modified human stem cells, a team of UC Davis scientists has developed an improved gene therapy strategy that in animal models shows promise as a functional cure for the human immunodeficiency virus (HIV) that causes AIDS.  The achievement, which involves an improved technique to purify populations of HIV-resistant stem cells, opens the door for human clinical trials that were recently approved by the U.S. Food and Drug Administration.

Study funded on the clinical, financial effectiveness of telemedicine versus telephone consultations

December 16, 2014

The U.S. Department of Health and Human Services has awarded a $1,198,384 grant to UC Davis pediatrician James Marcin to investigate how telemedicine consultations in emergency departments impact clinical outcomes, including cost effectiveness, compared with telephone consultations. 

Too much, too little, just right

December 15, 2014

Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer. Too little Rbm38 allows p53 overexpression, causing premature aging. The study was published in the journal PNAS on Dec. 15. 

UC Davis Multidisciplinary ALS Clinic named a Certified Treatment Center of Excellence by the ALS Association

December 12, 2014

The UC Davis Multidisciplinary ALS Clinic has been named an ALS Association Certified Treatment Center of Excellence, in acknowledgement of its meeting the highest levels of established national standards of care for the management of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease.

Preeclampsia during mother's pregnancy associated with greater autism risk

December 8, 2014

Children with autism spectrum disorder (ASD) were more than twice as likely to have been exposed in utero to preeclampsia, and the likelihood of an autism diagnosis was even greater if the mother experienced more severe disease, a large study by researchers with the UC Davis MIND Institute has found.

CDC identifies UC Davis as Ebola treatment center

December 3, 2014

The U.S. Centers for Disease Control and Prevention identified UC Davis Medical Center as one of the 35 U.S. hospitals designated as an Ebola treatment center. The designation, announced Dec. 2,  was a collaborative decision made by state and local health authorities and University of California (UC) leadership. UC San Francisco was also designated, with the three remaining UC medical centers expected to receive treatment-center designation soon.

UC Davis Medical Center named 2014 Leapfrog Top Hospital for the third consecutive year

December 2, 2014

UC Davis Medical Center ranks among The Leapfrog Group's list of Top Hospitals for 2014, an elite distinction that recognizes UC Davis for meeting tough national standards for safety and quality. The annual award, widely acknowledged as one of the most competitive awards a U.S. hospital can receive, is given to the highest performing hospitals participating in the Leapfrog Hospital Survey.

Perceptions, referrals by medical providers affect mental-health treatment disparities

December 1, 2014

Disparities in mental-health treatment are known to be associated with patients’ racial and ethnic backgrounds. Now, a large study by researchers with UC Davis has found one possible reason for those disparities: Racial and ethnic minorities are less likely to be assessed and referred for treatment by their medical providers.

November 2014arrow

International study reveals the genetics of malaria-carrying mosquitoes

November 27, 2014

More than 100 scientists, including a team of UC Davis molecular biologists, have sequenced the genomes of 16 Anopheles mosquito species to help define the characteristics that make some of them uniquely capable of transmitting malaria parasites to humans.

'Tis the season to indulge in walnuts

November 13, 2014

Researchers at UC Davis and other institutions have found that diets rich in whole walnuts or walnut oil slowed prostate cancer growth in mice. In addition, both walnuts and walnut oil reduced cholesterol and increased insulin sensitivity.

National study provides insights into childhood head injuries

November 12, 2014

This week’s issue of the New England Journal of Medicine features an article that highlights an unprecedented analysis of the nation’s childhood head injuries.

UC Davis investigational medication used to resolve life-threatening seizures in children

November 12, 2014

In its first clinical application in pediatric patients, an investigational medication developed and manufactured at UC Davis has been found to effectively treat children with life-threatening and difficult-to-control epileptic seizures without side effects, according to a research report by scientists at UC Davis and Northwestern University.

Lung cancer screening for Medicare patients coming soon to UC Davis

November 10, 2014

UC Davis Medical Center is preparing to screen seniors on Medicare who meet the criteria for lung cancer screening using low-dose computed tomography (CT).

UC Davis Medical Center prepared for potential Ebola cases

November 6, 2014

As the largest Ebola epidemic in history continues in West Africa, UC Davis Health System is prepared to safely screen, isolate and care for a patient who arrives at the medical center suffering from the disease.

Immunotherapy for cancer toxic with obesity

November 3, 2014

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. [en español]

October 2014arrow

UC Davis researchers examine risks, benefits of chemotherapy for early-stage breast cancer

October 31, 2014

Treatment for early stage breast cancer is highly effective, and for many women considering treatment choices, chemotherapy may add little to an already high long-term survival rate. Joy Melnikow, professor in the Department of Family and Community Medicine and Director of the Center for Healthcare Policy and Research at UC Davis, is working to define the potential long-term harms of chemotherapy for these patients, so they can be weighed against the potential benefits.

UC Davis MIND Institute researchers to establish new tests to evaluate cognitive growth in people with intellectual disability

October 30, 2014

Researchers with the UC Davis MIND Institute will develop and evaluate tests designed to measure and track changes in the cognitive functioning of people who typically are difficult to assess accurately: those with an intellectual disability, formerly termed mental retardation. The research will be funded through a new, five-year, $3.2 million grant from the National Institutes of Health (NIH).

UC Davis Medical Center receives "A" rating on Hospital Safety Score

October 29, 2014

UC Davis Medical Center was again honored with an “A” grade on The Leapfrog Group’s Hospital Safety Score for its overall capacity to keep patients safe from preventable harm.

UC Davis researchers find promising new treatment approach for ischemic stroke

October 27, 2014

A team of UC Davis scientists has found that administering a small molecule – purmorphamine – in animal models after a stroke results in multiple protective effects, including reducing the size of the stroke, decreasing inflammation and increasing markers for nerve regeneration.

Anti-cancer drug found effective against common stem cell transplant complication

October 24, 2014

Researchers at UC Davis have found that the drug bortezomib effectively treats chronic graft-versus-host disease (GVHD), a common and debilitating side effect from allogeneic hematopoietic stem cell transplants.

Distinguished cancer prevention researcher to lead public health sciences at UC Davis

October 21, 2014

Brad Pollock, a leading researcher on the incidence and control of childhood and adolescent cancer, has become chair of the Department of Public Health Sciences at the UC Davis School of Medicine.

NCI awards UC Davis $1.5 million to innovate robotic surgery for head and neck cancers

October 21, 2014

The National Cancer Institute (NCI) has awarded UC Davis principal investigators Laura Marcu and Gregory Farwell $1.5 million to adapt UC Davis-developed biophotonic technology to a robotic surgical device in hopes of dramatically improving the precision of head and neck cancer surgery.

Tarantula venom illuminates electrical activity in live cells

October 20, 2014

Researchers at the University of California, Davis, Lawrence Berkeley National Laboratory and Marine Biological Laboratory in Woods Hole, Massachusetts, have created a cellular probe that combines a tarantula toxin with a fluorescent compound to help scientists observe electrical activity in neurons and other cells. The probe binds to a voltage-activated potassium ion channel subtype, lighting up when the channel is turned off and dimming when it is activated. 

Randi Jenssen Hagerman receives C. Anderson Aldrich Award from American Academy of Pediatrics

October 15, 2014

Randi Jenssen Hagerman, medical director of the UC Davis MIND Institute, Distinguished Professor of Pediatrics and Endowed Chair in Fragile X Research and Treatment, has received the prestigious C. Anderson Aldrich Award in Child Development for her outstanding contributions in the field of child development from the American Academy of Pediatrics, the professional organization for pediatricians in the United States.

Cancer Center wins $1.7 million NCI grant to study novel cancer treatment

October 10, 2014

A multidisciplinary team at UC Davis will embark on research to determine whether combining a novel type of immunotherapy with radiation and chemotherapy can make treatment for sarcoma, breast and pancreatic cancers more effective.

Probiotic decreases the risk of necrotizing enterocolitis

October 10, 2014

A team of UC Davis and University of Arizona researchers discovered that adding the bacteria Bifidobacterium longum subsp. infantis (B. infantis) to formula fed to newborn rats reduced the incidence of necrotizing enterocolitis, an often deadly intestinal infection.

UC Davis recognized as an industry leader in cardiac rehabilitation

October 8, 2014

The Cardiac Rehabilitation and Preventive Cardiology Program at UC Davis Health System has been certified by the American Association of Cardiovascular and Pulmonary Rehabilitation for leadership in improving quality of life, enhancing standards of care and offering advanced practices for patients recovering from cardiac events or interventions.

Shinjiro Hirose joins UC Davis as chief of pediatric general, thoracic and fetal surgery

October 2, 2014

Shinjiro Hirose, a nationally recognized fetal and pediatric surgeon, has joined the faculty of the UC Davis School of Medicine as chief of the newly established Division of Pediatric General, Thoracic and Fetal Surgery in the Department of Surgery.

Research Center for Behavioral Health launched at UC Davis

October 1, 2014

UC Davis Health System officials and California Senate leader Darrell Steinberg today announced the founding of a unique academic research center designed to improve mental health in California and serve as a national model for advancing innovative research in neuroscience, as well as the prevention of and early interventions in mental illness.

September 2014arrow

UC Davis neuroscientists receive prestigious NIH BRAIN Initiative Awards

September 30, 2014

Two UC Davis research teams developing transformational technologies to understand the dynamics of the neural circuitry underlying behavior and cognition have received awards from the federal Brain Research through Advancing Innovative Technologies (BRAIN) Initiative, a presidential grand Challenge enterprise.

Higher nurse-to-patient standard improves staff safety

September 23, 2014

A 2004 California law mandating specific nurse-to-patient staffing standards in acute care hospitals significantly lowered job-related injuries and illnesses for both registered nurses and licensed practical nurses, according to a UC Davis study published online in the International Archives of Occupational and Environmental Health.

Mothers of children with autism less likely to have taken iron supplements during pregnancy

September 21, 2014

Mothers of children with autism are significantly less likely to report taking iron supplements before and during their pregnancies than the mothers of children who are developing normally, a study by researchers with the UC Davis MIND Institute has found.

David Schrimmer joins UC Davis as chief of maternal-fetal medicine

September 18, 2014

David B. Schrimmer, a highly respected obstetrician and gynecologist who is expert in the management of complex pregnancies, including multiple gestations and those requiring fetal therapy, has joined the faculty of the UC Davis School of Medicine in the Department of Obstetrics and Gynecology as professor and chief of the Division of Maternal-Fetal Medicine.

UC Davis Medical Center named one of the nation's top hospitals with great heart programs

September 18, 2014

UC Davis Medical Center has been named one of “100 Hospitals and Health Systems With Great Heart Programs” for 2014-15 by Becker's Hospital Review. In developing the list, the publication's editorial team considered hospitals that “lead the nation in cardiovascular and thoracic healthcare.”

Katherine Rauen named 2014 Rare Champion of Hope honoree

September 15, 2014

Katherine Rauen, professor in the Department of Pediatrics and a physician-scientist affiliated with UC Davis MIND Institute and UC Davis Children’s Hospital, has received the 2014 Rare Champion of Hope Honoree in Science.

Sleep disorders widely undiagnosed in individuals with multiple sclerosis

September 12, 2014

In what may be the largest study of sleep problems among individuals with multiple sclerosis (MS), researchers at UC Davis have found that widely undiagnosed sleep disorders may be at the root of the most common and disabling symptom of the disease: fatigue.

UC Davis, University of Washington launch project to develop depression care for older adults

September 5, 2014

UC Davis and the University of Washington are implementing a project to develop innovative new models of care for depression in older adults through a $2.5 million grant from the California-based Archstone Foundation, a private grant-making organization whose mission is to contribute toward the preparation of society in meeting the needs of an aging population. The grant launches Archstone Foundation’s Depression in Late Life Initiative to improve the quality of life for older adults suffering from depression. 

Breast vs. bottle feeding in rhesus monkeys

September 3, 2014

Infant rhesus monkeys receiving different diets early in life develop distinct immune systems that persist months after weaning, a study by researchers from UC Davis, the California National Primate Research Center (CNPRC) at UC Davis and UC San Francisco has shown. The study, which compares breast- and bottle-fed infants, appears online September 3 in Science Translational Medicine. [en español]

Brief depression questionnaires could lead to unnecessary antidepressant prescriptions

September 2, 2014

Short questionnaires used to identify patients at risk for depression are linked with antidepressant medications being prescribed when they may not be needed, according to new research from UC Davis Health System published in the September-October issue of the Journal of the American Board of Family Medicine.

August 2014arrow

The early cost of HIV

August 29, 2014

Researchers at UC Davis have made some surprising discoveries about the body’s initial responses to HIV infection. Studying simian immunodeficiency virus (SIV), the team found that specialized cells in the intestine called Paneth cells are early responders to viral invasion and are the source of gut inflammation by producing a cytokine called interleukin-1 beta (IL-1β).

UC Davis MIND Institute researchers launch study examining autism in girls

August 28, 2014

Autism is far more common in boys than girls - affecting 1 in 54 boys and 1 in 252 girls — but little is known about biological differences between boys and girls with autism. A new study, called the ‘Girls with Autism — Imaging of Neurodevelopment’ or GAIN Study, led by researchers at the UC Davis MIND Institute will explore those differences in very young girls with autism.

Young earthquake survivor thankful to UC Davis Children's Hospital

August 27, 2014

Nicholas Dillon, the brave 13-year-old who survived after a chimney collapsed on him in his home during the Napa Valley earthquake last Saturday, is in good condition in UC Davis Children’s Hospital. Dillon’s recovery has garnered national and international media attention. He was interviewed from his hospital room in the Pediatric Intensive Care Unit yesterday by NBC News, among other media outlets.

Introducing the multi-tasking nanoparticle

August 26, 2014

mKit Lam and colleagues from UC Davis and other institutions have created dynamic nanoparticles (NPs) that could provide an arsenal of applications to diagnose and treat cancer. Built on an easy-to-make polymer, these particles can be used as contrast agents to light up tumors for MRI and PET scans or deliver chemo and other therapies to destroy tumors. In addition, the particles are biocompatible and have shown no toxicity. The study was published online today in Nature Communications.

Door-to-door fundraising scam does not benefit UC Davis Children's Hospital

August 20, 2014

The Sacramento-based UC Davis Health System reminds northern California residents that it never seeks donations using door-to-door solicitors and does not work with organizations that use this fundraising approach.

Novel drug action against solid tumors explained

August 11, 2014

Researchers at UC Davis, City of Hope, Taipai Medical University and National Health Research Institutes in Taiwan have discovered how a drug that deprives the cells of a key amino acid specifically kills cancer cells.

UC Davis launches a clinic to treat thoracic outlet syndrome

August 7, 2014

UC Davis Health System has opened a clinic dedicated to treating a rare and complex condition called thoracic outlet syndrome (TOS), which occurs when blood vessels or nerves running from the upper body through the arm become compressed, causing problems ranging from reduced mobility and pain to life- and limb-threatening blood clots. It is most often the outcome of trauma, repetitive movements or extra ribs that are present at birth.

Pan awarded grant to test 'smart' chemotherapy drug for bladder cancer

August 7, 2014

UC Davis Comprehensive Cancer Center oncologist Chong-Xian Pan has received a $650,000 grant from the VA Northern California Health Care System to conduct the first clinical trial of a novel chemotherapy-delivery drug he developed for bladder cancer patients.