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March 2017arrow

Hitting cancer with high-intensity ultrasound and immunotherapy

March 23, 2017

In a new study published today in JCI Insight, UC Davis researchers have shown that combining high-intensity focused ultrasound with two immunotherapies (a PD-1 checkpoint inhibitor and TLR9 agonist) can produce excellent response rates in mouse models of epithelial cancer. They also found that, for the combination to be effective, immunotherapies must come first.

UC Davis researchers investigate adult blood-clotting drug for use in severely injured children

March 14, 2017

UC Davis emergency medicine researchers have been awarded a grant from the National Institutes of Health (National Heart, Lung, and Blood Institute) to investigate the safety and efficacy of a drug known to stop bleeding in injured adults for use in cases of pediatric trauma.

Developing new collaborations and technologies

March 7, 2017

With a $1 million grant from the National Science Foundation (NSF), UC Davis and Boston University will focus on establishing partnerships with industry, academe and government that lead to the development of innovative biophotonic technologies for use in medicine and other scientific disciplines.

University of California, Stanford partner on research to improve health in California and nationwide

March 7, 2017

The University of California Biomedical Research Acceleration, Integration, and Development program (UC BRAID) and Stanford University have formed an alliance to combine resources and develop a coordinated approach to research targeting the health of Californians – a partnership that can serve as a model for collaborations throughout the country.

UC Davis joins national consortium to find regenerative treatments for dental and craniofacial tissues

March 7, 2017

UC Davis will join other California research institutions in a three-year, $12 million effort to find regenerative treatments for dental, oral and craniofacial deformities and injuries.

Doctors and patients often disagree on pain treatment goals

March 6, 2017

Disagreements between doctors and patients over the priorities of pain treatment are common during primary care office visits, new research from UC Davis Health shows. Patients hope to reduce pain intensity and identify the cause, while physicians aim to improve physical function and reduce medication side effects, including dependency.

Cerebrospinal fluid shows promise as autism biomarker

March 6, 2017

Researchers from the UC Davis MIND Institute, University of North Carolina (UNC) and other institutions have found that altered distribution of cerebrospinal fluid (CSF) in high-risk infants can predict whether they will develop autism spectrum disorder (ASD). The study appears today in the journal Biological Psychiatry.

February 2017arrow

UC Davis computational molecular biologist named Sloan fellow to study genetic causes of complex disorders

February 27, 2017

Fereydoun Hormozdiari, an early-career UC Davis scientist, has been named a 2017 Alfred P. Sloan Research Fellow in Computational & Evolutionary Molecular Biology. He is one of 126 scholars to receive the prestigious award, which comes with $60,000 over two years to conduct leading-edge research.

Research linking obesity to immune function and disease gets funding boost

February 23, 2017

Researchers at UC Davis have received $3.2 million in federal funds to further investigate how obesity and inflammation affect the body’s immune system in fighting cancer.

Placenta provides time capsule for autism studies

February 21, 2017

In two recent studies, researchers at UC Davis have shown that the placenta can provide critical information about early changes to the intra-uterine environment that may influence fetal development and ultimately, children’s brains.

Language barriers may interfere with access to kidney transplantation

February 10, 2017

Language barriers may hinder U.S. kidney transplant candidates’ access to kidney transplantation, according to a new study in the Clinical Journal of the American Society of Nephrology.  Led by a team from Cedars-Sinai, UCLA Health and UC Davis Health, the research suggests that patients who primarily speak a language other than English may face disparities that keep them from completing their kidney transplant evaluations and, ultimately, from receiving a transplant.

Poverty and high neighborhood murder rates increase depression in older adults

February 9, 2017

Older adults who live in poor and violent urban neighborhoods are at greater risk for depression, a study by researchers from UC Davis, the University of Minnesota and other institutions published Jan. 23 in the journal Health & Place has found.

UC Davis study finds mold, bacterial contaminants in medical marijuana samples

February 7, 2017

UC Davis physician researchers have found that medical marijuana contains multiple bacterial and fungal pathogens that may cause serious and even fatal infections. They warn that smoking, vaping or inhaling aerosolized marijuana could pose a grave risk to patients, especially those with leukemia, lymphoma, AIDS or conditions requiring immune-suppressing therapies.

January 2017arrow

How maternal immune response to allergies may affect neurodevelopment

January 31, 2017

Researchers at UC Davis have published a study that illustrates how maternal immune activation could affect neurodevelopment in offspring.

Prior DUIs predict future criminal activity among firearm owners

January 30, 2017

Among individuals who legally purchased handguns in California, prior convictions for driving under the influence (DUI) and other alcohol-related crimes were associated with a substantial increase in risk for subsequent violent or firearm-related crime, according to a study published Jan. 30 in Injury Prevention by the UC Davis Violence Prevention Research Program.

Faulty DNA error correction genes set stage for familial gastric cancer

January 19, 2017

A large team of researchers from UC Davis and several European and Latin American institutions have identified genetic variations that contribute to familial gastric cancer. These inherited mutations, which affect the PALB2, BRCA1 and RAD51C genes and have been implicated in other cancer types, impair a critical DNA repair mechanism called homologous recombination. These findings could improve preventive care, as well as provide targets for new therapies. The study was published last month in the journal Gastroenterology.

Many late-stage lung cancer patients do not get treatment

January 18, 2017

A national study by researchers at UC Davis Comprehensive Cancer Center has found that a significant number of lung cancer patients are not receiving treatment. Based on data between 1998 and 2012 from the National Cancer Database, 21 percent of patients (190,539) with non-small cell lung cancer (NSCLC) received no specific cancer treatment, such as chemotherapy, radiotherapy or surgery. Many of the untreated patients were women, elderly, minorities, low income and uninsured.

UC Davis Health welcomes Beijing medical equipment company

January 9, 2017

UC Davis Health has entered into an agreement with Top Grade Health Care to establish a translational research and development center to advance the treatment of patients with cancer.