Frontiers in Pharmacology Lecture Series

Each year the Department of Pharmacology invites distinguished researchers to present their work on topics broadly related to pharmacology. Topics range from those closely aligned with the research interests of the department to areas of interest to researchers across the UC Davis campus and the UC Davis School of Medicine.

Past Seminars

2023


January 17, 2023

Speaker: Daniel Choquet, Ph.D., Director, Dynamic organization and function of Synapses, Bordeaux Neurocampus

Title: "Interplay between dynamic nanoscale glutamatergic synapse organization and function" (PDF)

Host: Johannes Hell, Ph.D., Professor, Department of Pharmacology


February 21, 2023

The seminar has been cancelled!

Speaker: Daniela Kaufer, Ph.D., Department of Integrative Biology and Helen Wills Neuroscience Institute, Associate Dean of Biological Sciences, University of California, Berkley

Host: Angela Gelli, Ph.D., Professor, Department of Pharmacology

See the flyer »


April 4, 2023

2 p.m. in Tupper Hall 2133/2135 and via Zoom

Speaker: Zhao Wang, Ph.D., Associate Professor, Departments of Diabetes and Cancer Metabolism, City of Hope

Title: “Protein Folding and Glucose Metabolism: Two-way Traffic in Cardiac Disease” (PDF)

Host: Yang Kevin Xiang, Ph.D., Professor, Department of Pharmacology


April 18, 2023

Speaker: Fabrice Dabertrand, Ph.D., Associate Professor, Departments of Anesthesiology and Pharmacology, University of Colorado, Anschutz Medical Campus

Title: "Impact of cerebral small vessel disease on neuronal plasticity" (PDF)

Host: Manuel Navedo, Ph.D., Professor, Department of Pharmacology


May 2, 2023

Speaker: Girija Raman, Ph.D., M.B.A., Associate Director of Corporate Development, Gilead

Title: "Anatomy of a Pharmaceutical Deal -Discovery to Acquisition" (PDF)

Host: Heike Wullf, Ph.D., Professor, Department of Pharmacology


June 20, 2023

Speaker: Luis G Carvajal-Carmona, Ph.D., Associate Vice Chancellor for Academic Diversity Office of Diversity, Equity and Inclusion, Professor and Auburn Community Cancer Endowed Chair in Basic Science, Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis

Title: "Precision Health Equity: the intersection between modern medicine and health disparities" (PDF)

Host: Elva Diaz, Ph.D., Professor, Department of Pharmacology


November 7, 2023

Speaker: David Liem, M.D., Ph.D., Project Scientist, Med: Internal Medicine Cardiology, UC Davis School of Medicine

Title: “A Natural Language Processing Approach to Unveil Novel Therapeutic Mechanisms and Targets in Heart Failure” (PDF)

Host: Leighton T. Izu, Ph.D., Professor, Department of Pharmacology


2022


January 13, 2022

11 a.m. (PST) Via Zoom

Speaker: Roy Ben-Shalom, Assistant Professor in Neurology and the MIND Institute, UC Davis

Title: “Simulating neurodevelopmental disorders: from the channel to the circuit” (PDF)

Host: Julie Bossuyt, Ph.D., Associate Professor, Department of Pharmacology

Joint Seminar - Pharmacology - Physiology and Membrane Biology


February 15, 2022

11 a.m. (PST) Via Zoom

Speaker: Michael Burton, Assistant Professor of Department of Neuroscience, University of Texas at Dallas

Title: "Cell and Sex-Specific effects of TLR4 in Neuroimmune interactions in acute pain states” (PDF)

Host: Elva Diaz, Ph.D., Professor, Department of Pharmacology


March 15, 2022

Speaker: Jin Zhang, Professor, Department of Pharmacology, University of California, San Diego

Title: “Illuminating the Biochemical Activity Architecture of the Cell” (PDF)

Hosts: Madeline Nieves-Cintron, Ph.D. and Lin Tian, Ph.D.

Joint Seminar - Pharmacology and Biochemistry


April 19, 2022

Speaker: Jennifer Davis, Associate Professor, Departments of Lab Medicine and Pathology & Bioengineering, Director of the Center for Cardiovascular Biology, Associate Director of The Institute for Stem Cell & Regenerative Medicine, School of Medicine, University of Washington

Title: "Regulators of Cardiac Fibroblast Fate & Fibrosis" (PDF)

Host: Julie Bossuyt, Ph.D., Associate Professor, Department of Pharmacology


May 3, 2022

Speaker: Robert Edwards, Professor, M.D., Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco

Title: "The Frequency Dependence of Neurotransmitter Release" (PDF)

Host: Johannes W. Hell, Ph.D., Professor, Department of Pharmacology


May 17, 2022

Speaker: Nikki Posnack, Assistant Professor, Dept. of Pediatrics, Dept of Pharmacology and Physiology, The George Washington University

Title: "Plastic – not so fantastic. Evaluating medical device biocompatibility using cardiac models" (PDF)

Host: Crystal Ripplinger, Ph.D., Professor, Department of Pharmacology


October 18, 2022

Speaker: Jan Christoph, Ph.D., Assistant Professor, Cardiovascular Research Institute, University of California, San Francisco

Title: "High-Resolution Imaging of the Electromechanics of the Heart" (PDF)

Host: Ye Chen-Izu, Ph.D., Professor, Department of Pharmacology


November 9, 2022

10:30 a.m. in Tupper Hall Rm 2133/2135 and via Zoom

Speaker: Michael A Colman, Ph.D., F.H.E.A., Associate Professor, Department of Biological Sciences, Systems Physiology, University of Leeds, U.K.

Title: "Heterogeneity, variability, and cardiac dysfunction: from dyad to ECG" (PDF)

Hosts: Eleonora Grandi, Ph.D. and Haibo Ni, Ph.D.


November 15, 2022

Speaker: Ade Aromolaran, Ph.D., Associate Professor, Department of Surgery, Division of Cardiothoracic Surgery, Investigator, Nora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), U2M2 Program in Molecular Medicine

Title: "Illuminating the Role of the Delayed Rectifier K Channels in Heart" (PDF)

Host: Ele Grandi, Ph.D., Professor, Department of Pharmacology

2021


March 16, 2021

Speaker: Weijian Yang, Ph.D., Assistant Professor, Department of Electrical and Computer Engineering, University of California, Davis

Lecture: “All-optical Interrogation of Neural Circuits” (PDF)

Host: Johannes W. Hell, Ph.D.


April 20, 2021

Speaker: Jiang Chang, M.D., Ph.D., FAPS, Professor, Chancellor EDGES Fellow, Center for Genomic and Precision Medicine, Texas A&M University

Lecture: "Rho Signaling: From Cardiac Remodeling to Hydrocephalus" (PDF)

Host: Kevin Xiang, Ph.D.


May 18, 2021

Speaker: Devin Horton, Ph.D., Graduate Diversity Officer: Science, Technology, Engineering and Mathematics (STEM), University of California, Davis

Lecture: "Equity in Academia: A Group Project" (PDF)

Host: Elva Diaz, Ph.D.


June 15, 2021

Speaker: Sue Vang, Engagement and Zero Waste Program Manager, University of California, Davis | Sustainability Office

Lecture: "Greening Your Workplace with UC Davis Sustainability" (PDF)

Host: Andrew Edwards, Ph.D.


November 2, 2021

Speaker: Gabriela Popescu, Professor, Department of Biochemistry, Jacobs School of Medicine & Biomedical Sciences

Lecture: “NMDA Receptors as Calcium Channels” (PDF)

Host: Johannes W. Hell, Ph.D.


2020


January 21, 2020

Speaker: Thomas M. Vondriska, Ph.D., Professor of Anesthesiology, Medicine & Physiology David Geffen School of Medicine at UCLA

Lecture: “Cardiovascular Epigenomes: From Chromatin Fiber to Human Populations” (PDF)

Host: Julie Bossuyt, Ph.D.


April 21, 2020

Speaker: Jerod Denton, Ph.D., Professor, Department of Anesthesiology, Vanderbilt University

Host: Heike Wulff, Ph.D.


May 19, 2020

Speaker: Erika Boerman, Ph.D., Assistant Professor, Department Med Pharmacology and Physiology, University of Missouri

Host: Manuel Navedo, Ph.D.


June 23, 2020

Speaker: Federica Accornero, Ph.D., Associate Professor, The Ohio State University, Department of Physiology and Cell Biology

Host: Crystal Ripplinger, Ph.D.


September 15, 2020

Speaker: Dr. Osama Harraz, Research Assistant Professor, Department of Pharmacology, Larner College of Medicine, University of Vermont

Title: “PIP2: The maestro of the cerebral blood flow symphony” (PDF)

Host: Madeline Nieves-Cintron, Ph.D.


October 20, 2020

Speaker: Dr. Federica Accornero, Assistant Professor, Physiology and Cell Biology, The Ohio State University

Title: "Insights into post-transcriptional control of gene expression in the heart" (PDF)

Host: Crystal Ripplinger, Ph.D.


November 17, 2020

Speaker: Dr. Laurent Groc, Directeur Recherche CNRS, Group Leader, Directeur Adjoint, Institut Interdisciplinaire Neuroscience (IINS), Centre Broca Nouvelle-Aquitaine, CNRS – Université de Bordeaux

Title: “INMDA receptor signaling: old actor, new vista” (PDF)

Host: Johannes W. Hell, Ph.D.


2019


January 15, 2019

Speaker: Hong Chen, Ph.D., Associate Professor of Surgery, Boston Children’s Hospital, Harvard Medical School

Lecture: “Endocytic Regulation of Cardiovascular Disease”

Host: Kevin Xiang, Ph.D.


February 12, 2019

Speaker: James Letts, Ph.D., Associate Professor, Dept Of Molecular and Cellular Biology, UC Davis

Lecture: “Structures of Respiratory Supercomplex I+III2 Suggest CoQ Channeling is Inefficient and Reveal Conformational Crosstalk”

Host: Johannes Hell, Ph.D.


February 19, 2019

Speaker: Filip Van Petegem, Ph.D., Professor, Department of Biochemistry & Molecular Biology, The University of British Columbia

Lecture: “Disease mutations at high resolution: structural insights into Calcium-selective channels”

Host: Don Bers, Ph.D.


March 19, 2019

Speaker: David J. Lefer, Ph.D. , Professor of Pharmacology, Director, Cardiovascular Center of Excellence, LSU Health New Orleans

Lecture: "Renal Sympathetic Denervation in Heart Failure"

Host: Kevin Xiang, Ph.D.


April 16, 2019

Speaker: Long-Sheng Song, M.D., M.S., Professor, Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine

Lecture: “Decoding Junctophilin-2-mediated Transcriptome in Stressed Heart”

Host: Ye Chen-Izu, M.S., Ph.D.


May 21, 2019

Speaker: Carlo Brugnara, M.D., Professor of Pathology, Pathology, Boston Children’s Hospital, Harvard Medical School

Lecture: "Red blood cell hydration Status: from sickle cell disease to hereditary xerocytosis"

Host: Heike Wulff, Ph.D.


June 18, 2019

Speaker: Na Li, Ph.D., Assistant Professor, Molecular Physiology & Biophysics, Baylor College of Medicine

Lecture: “The emerging role of Inflammasome in cardiac arrhythmias.”

Host: Ele Grandi, Ph.D.


September 12, 2019

Speaker: Matthew B. Dalva, Ph.D., Professor and Vice Chair, Department of Neuroscience, Director, Jefferson Synaptic Biology Center, Thomas Jefferson University

Lecture:Synapse formation and plasticity: effects of biological-sex and synaptic nanostructure” (PDF)

Host: Elva Diaz, Ph.D.


September 17, 2019

Speaker: Maria Kurnikova, Ph.D., Associate Professor, Department of Chemistry at Carnegie Mellon University

Lecture:Deciphering Molecular Mechanisms of the Glutamate Receptor Function”  (PDF)

Host: Elva Diaz, Ph.D.


October 15, 2019

Speaker: Zixi (Jack) Cheng, Ph.D., Associate Professor, University of Central Florida

Lecture: “Structural and Functional Mapping of Brain-Heart Connection and Remodeling” (PDF)

Host: Chao-Yin Chen, Ph.D.


November 5, 2019

Speaker: Manu Ben-Johny, Ph.D., Assistant Professor of Physiology and Cellular Biophysics, Columbia University

Lecture: "Tuning calmodulin feedback of calcium and sodium channels in health and disease" (PDF)

Host: Johannes W. Hell, Ph.D.


December 3, 2019

Speaker: Joshua I Goldhaber, M.D., Director, Division of Applied Cell Biology and Physiology at Cedars-Sinai Medical Center

Lecture: "Cardiac calcium regulation in mice with genetically modified calcium efflux proteins and in rats with Heart Failure with Preserved Ejection Fraction" (PDF)

Host: Leighton Izu, Ph.D.

2018


January 16, 2018

Lecture: "Exploring and Exploiting the Spatial Constraints of Local Signaling" (PDF)

Speaker: John Scott, Ph.D., University of Washington

Host: Manuel Navedo, Ph.D.


January 19, 2018

Friday, 2 p.m., GBSF Rm 6202

Lecture: "Therapeutic interventions for heart disease" (PDF)

Speaker: Mark Ziolo, Ph.D., Ohio State University Medical Center

Host: Don Bers, Ph.D.


February 20, 2018

Speaker: Roger Nicoll M.D., University of California, San Francisco

Host: Johannes Hell, Ph.D.


March 20, 2018

Lecture: “Calcium waves, nonlinear dynamics, and stochasticity in atrial myocytes” (PDF)

Speaker: Yohannes Shiferaw, Ph.D., California State University, Northridge

Host: Daisuke Sato, Ph.D.


April 17, 2018

Speaker: Miao Zhang, Ph.D., Chapman University, School of Pharmacy

Host: Heike Wulff, Ph.D.


May 15, 2018

Speaker: Nancy Kanagy, Ph.D., University of New Mexico

Host: Manuel Navedo, Ph.D.


June 19, 2018

Speaker: Alexey Glukhov, Ph.D., University of Wisconsin, School of Medicine

Host: Eleonora Grandi, Ph.D.


September 18, 2018

Speaker: Mark Mercola, Ph.D., Professor, Department of Medicine, Stanford University School of Medicine, Stanford Cardiovascular Institute

Host: Ele Grandi, Ph.D.


October 16, 2018

Speaker: Anthony J. Baker, Ph.D., Professor of Medicine, University of California, San Francisco, VA Medical Center, Cardiology Division

Lecture: “A new approach to treat right ventricular failure: targeting α1 adrenergic receptors” (PDF)

Host: Ye Chen-Izu, M.S., Ph.D.


November 8, 2018

Thursday, 2 p.m.

Speaker: Ingo Greger, Ph.D., Medical Research Council, Laboratory of Molecular Biology, Cambridge Biomedical Campus

Lecture: “Structural and functional architecture of the AMPA receptor extracellular region” (PDF)

Host: Johannes Hell, Ph.D.


December 4, 2018

Speaker: David Schneider, Ph.D., Assistant Professor, Center for Neural Science, New York University

Lecture: “Cortical circuits for predicting the future” (PDF)

Host: Crystal Ripplinger, Ph.D.

2017


January 17, 2017

Lecture: "Neuron-specific approaches for altering cardiac autonomic tone in health and disease" (PDF)

Speaker: Matthew Kay, Ph.D., Associate Professor, BME Associate Chair for Research and Graduate Affairs BME, George Washington University

Host: Crystal Ripplinger, Ph.D.


February 21, 2017

Lecture: "Multiple Roles for Protein Acetylation in Heart Failure" (PDF)

Speaker: Tim McKinsey, Ph.D., Associate Professor and Associate Division Head for Translational Research, Division of Cardiology, University of Colorado, Denver

Host: Julie Bossuyt, Ph.D.


March 10, 2017

Friday, 4 p.m.

Lecture: "Massively Parallel All-Optical Cardiac Electrophysiology" (PDF)

Speaker: Emilia Entcheva, Ph.D., Professor, BME, George Washington University

Host: Daisuke Sato, Ph.D.


March 21, 2017

Lecture: "Cardiomyocyte CaMkinase II regulates inflammatory and fibrotic responses associated with development of heart failure" (PDF)

Speaker: Joan Heller Brown, Ph.D., Distinguished Professor, and Depart Chair Pharmacology, UCSD

Host: Don Bers, Ph.D.


April 18, 2017

Lecture: "Kinase Fusions in Cancer: From Model Systems to the Development of Novel Therapeutics" (PDF)

Speaker: Monika Davare, Ph.D., Research Instructor, Oregon Health and Science University

Host: Johannes Hell, Ph.D. and Mary Horne, Ph.D.


May 16, 2017

Lecture: "Endothelial KCachannels: Critical mediators of vascular tone in health and disease" (PDF)

Speaker: Andrew Braun, Ph.D., Associate Professor, Physiology and Pharmacology, Physiology, Cumming School of Medicine, University of Calgary

Host: Heike Wulff, Ph.D.


July 21, 2017

Lecture: "Physiology and Biophysics of Cardiac Pacemaking" (PDF)

Speaker: Catherine Proenza, Ph.D., Associate Professor, University of Colorado, Denver

Host: Eleonora Grandi, Ph.D.


September 14, 2017

Speaker: Kimberly Dodge-Kafka, Ph.D., University of Connecticut Health

Host: Don Bers, Ph.D.


September 19, 2017

Speaker: Martin Young, D.Phil, University of Alabama at Birmingham

Host: Kevin Xiang, Ph.D.


October 17, 2017

Lecture: "Molecular mechanisms of AMPA receptor delivery and stabilization during LTP" (PDF)

Speaker: Robert Malenka, Ph.D., Stanford University

Host: Johannes Hell, Ph.D.


November 7, 2017

Lecture: "The Transcription Factor, ATF6, Links ER Stress and Oxidative Stress Signaling in the Heart and is as Master Regulator of Cardiokine Secretion" (PDF)

Speaker: Chris Glembotski, Ph.D., San Diego State University

Host: Kevin Xiang, Ph.D.


November 9, 2017

Thursday, 12 p.m., Valley Hall 1010

Speaker: Johannes Backs, Ph.D., University of Heidelberg

Host: Don Bers, Ph.D. and Julie Bossuyt, Ph.D.


December 5, 2017

Lecture: "Role of NADPH Oxidase in Duchenne Muscular Dystrophy" (PDF)

Speaker: George Rodney, Ph.D., Baylor College of Medicine

Host: Ye Chen-Izu, Ph.D.


2016


February 16, 2016

Lecture: "From Chaos to Cures; controlling the complex spatiotemporal dynamics of cardiac arrhythmias using a theoretical, numerical and experimental integrative approach" (PDF)

Speaker: Flavio Fenton, Ph.D., Associate Professor, Georgia Tech, Atlanta, GA

Host: Daisuke Sato, Ph.D.


March 15, 2016

Lecture: "Translational opportunities in substance abuse and its co-morbidities through biased agonism at GPCRs" (PDF)

Speaker: Jennifer Whistler, Ph.D., Professor, Neurology, University of California, San Francisco

Host: Elva Diaz, Ph.D.


March 31, 2016

Lecture: "Dyadic Structure and Function in Cardiomyocytes: Implications for Heart Failure" (PDF)

Speaker: William E. Louch, Ph.D., Professor, Oslo University Hospital, Ullevål

Host: Eleonora Grandi, Ph.D.


April 19, 2016

Lecture: "Biophysical basis for cellular force transduction" (PDF)

Speaker: Alexander Dunn, Ph.D., Assistant Professor of Clinical Engineering, Stanford University, CA

Host: Ye Chen-Izu, Ph.D.


May 17, 2016

Lecture: "Quantitative Cardiovascular Systems Pharmacology: combining simulations and experiments to understand toxicity and efficacy of drugs" (PDF)

Speaker: Eric Sobie, Ph.D., Associate Professor, Mount Sinai Hospital, New York, NY

Host: Eleonora Grandi, Ph.D.


June 2, 2016

Thursday, 10 a.m.

Lecture: "Mechanical communication in cardiac cell synchronized beating" (PDF)

Speaker: Shelly Tzlil, Ph.D., Assistant Professor, Technion-Israel Inst of Tech, Haifa, Israel

Host: Kevin Xiang, Ph.D.


August 16, 2016

Speaker: Prasad Sathyamangla, Ph.D., Molecular Biology Researcher, Cleveland Clinic, Cleveland, Ohio

Host: Kevin Xiang, Ph.D.


September 27, 2016

Lecture: "An inner life of GPCRs" (PDF)

Speaker: Mark von Zastrow, M.D., Ph.D., Professor, Psychiatry and Cellularand Molecular Pharmacology, University of California, San Francisco

Host: Johannes Hell, Ph.D.


October 18, 2016

Lecture: "Sensory Functions of TRPA1 Channels in the Cerebral Endothelium" (PDF)

Speaker: Scott Earley, Ph.D., Professor, Pharmacology, University of Nevada, Reno

Host: Manuel Navedo, Ph.D.


October 19, 2016

Wednesday, 10 a.m.

Lecture: "A How the Brain Controls Blood Pressure: Role of (Pro)renin Receptor"

Speaker: Yumei Feng, M.D., Ph.D., Associate Professor, Pharmacology, University of Nevada, Reno

Host: Chao-Yin Chen, Ph.D.


November 15, 2016

American Heart Association and Society for Neuroscience Meetings


2015


January 20, 2015

Speaker: Ehud Isacoff, Ph.D., Professor of Neurobiology, University of California, Berkeley

Host: Manuel Navedo, Ph.D.


February 17, 2015

Lecture: "Caveolae as capacitors for energy and metabolism: Implications for cardiac injury, aging and diabetes" (PDF)

Speaker: Hemal Patel, Ph.D., Associate Professor and Director, UC San Diego Cardiac/Neuro Protection Laboratories

Host: Kevin Xiang, Ph.D.


March 09, 2015

(Monday, 4 p.m.)

Lecture: "Norepinephrine release from sympathetic nerves in cardiac slices and in vivo: real time recording using electrochemical micro carbon fiber electrodes" (PDF)

Speaker: Zhuan Zhou, Ph.D., Professor and Senior Investigator, Institute of Molecular Medicine, Peking University

Host: Don Bers, Ph.D.


April 06, 2015

(Monday, 1 p.m.)

Lecture: "Relationship between intracellular Ca2+ release and electrical excitability at intact heart level" (PDF)

Speaker: Ariel Escobar, Ph.D., Professor, School of Engineering, University of California, Merced

Host: Don Bers, Ph.D.


April 21, 2015

Lecture: "A structural driven kinetic cycle for the pore domain of a K+ channel" (PDF)

Speaker: Luis Cuello, Ph.D., Assistant Professor, Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, Texas

Host: Heike Wulff, Ph.D.


May 12, 2015

Lecture: "Targeting cell membrane transporters to develop new drugs" (PDF)

Speaker: Alan Verkman, M.D., Ph.D., Professor of Medicine and Physiology, Department of Medicine, University of California, San Francisco

Host: Heike Wulff, Ph.D.


September 15, 2015

Lecture: "Marrying Fibroblast Myocyte Electrophysiology in Native Myocardium: something old, something new, something borrowed, something blue" (PDF)

Speaker: Peter Kohl, Ph.D., Professor, Imperial College, London, UK

Host: Crystal Ripplinger, Ph.D.


October 20, 2015

Lecture: "Microtubule mechanics and mechanosignaling in the heart" (PDF)

Speaker: Benjamin Prosser, Ph.D., Assistant Professor of Physiology, University of Pennsylvania

Host: Ye Chen-Izu, Ph.D.


November 17, 2015

Lecture: "Insights into dynamics and allosteric communication in G-protein-coupled receptors" (PDF)

Speaker: Vaidehi Nagarajan, Ph.D., Principal Investigator, City of Hope, Beckman Research Institute, Duarte, CA

Host: Kevin Xiang, Ph.D.


December 08, 2015

Lecture: "Decalmodulation of voltage-gated CavCa2+ channels" (PDF)

Speaker: Amy Lee, Ph.D., Assistant Dean for Scientific Affairs, Carver College of Medicine, University of Iowa

Host: Johannes Hell, Ph.D.


December 15, 2015

(11 a.m.)

Lecture: "Dendritic compartmentalization of electrical and biochemical signaling" (PDF)

Speaker: Michael Higley, M.D., Ph.D., Assistant Professor of Neurobiology, Cellular Neuroscience, Neurodegeneration and Repair, New Haven, CT

Host: Johannes Hell, Ph.D.


2014


January 21, 2014

Speaker: Mark Shapiro, University of Texas

Host: Manuel Navedo, Ph.D.


February 13, 2014

(Thursday, 12 p.m.)

Speaker: Junko Kurokawa, Tokyo Medical and Dental

Host: Colleen Clancy, Ph.D.


February 14, 2014

(Friday, 4 p.m.)

Speaker: Annette Dolphin, London College

Host: Johannes Hell, Ph.D.


March 18, 2014

Lecture: "Integrins and Cytoskeletal Proteins in the Cardiac Myocyte: More than Glue and Struts" (PDF)

Speaker: Robert Ross, University of California, San Diego

Host: Ye Chen-Izu, Ph.D.


April 15, 2014

Lecture: "Proteomic strategies to identify novel extracellular matrix biomarkers of cardiac injury" (PDF)

Speaker: Merry Lindsey, The University of Mississippi

Host: Crystal Ripplinger, Ph.D.


May 12, 2014

(Monday, 3 p.m.)

Lecture: "Noninvasive mapping of cardiac electrophysiology and arrhythmias in the intact human heart" (PDF)

Speaker: Yoram Rudy, Washington University

Host: Colleen Clancy, Ph.D.


June 17, 2014

Lecture: "Molecular Mechanisms Regulating Trafficking of Synaptic Proteins" (PDF)

Speaker: Katherine Roche, NIH/NINDS

Host: Johannes Hell, Ph.D.


September 16, 2014

Lecture: "Regulated Delivery and Removal of Synaptic Machinery" (PDF)

Speaker: Andres Maricq, M.D., Ph.D., Professor of Biology and Adjunct Professor of Neurology, University of Utah, Salt Lake City

Host: Elva Diaz, Ph.D.


October 21, 2014

Speaker: Kang Shen, Ph.D., Professor, Department of Biology, Stanford, Palo Alto, CA

Host: Johannes Hell, Ph.D.


November 18, 2014

Speaker: Marta Filizola, Ph.D., Associate Professor of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York

Lecture: "Modern Computer-Aided Drug Discovery Approaches for G Protein-Coupled Receptors" (PDF)

Host: Colleen Clancy, Ph.D.


December 16, 2014

Lecture: "Targeting Mitochondria for Heart Failure Therapy" (PDF)

Speaker: Rong Tian, M.D., Ph.D., Professor, Anesthesiology and Pain Medicine, Bioengineering, and Adjunct Professor, Biochemistry, Pathology, University of Washington Medicine

Host: Kevin Xiang, Ph.D.


December 18, 2014

(Thursday, 12-1 p.m.)

Lecture: "Spatial and Temporal Aspects of cAMP Signaling in Cardiac Myocyte" (PDF)

Speaker: Robert Harvey, Ph.D., Professor, Molecular Biosciences, University of Nevada, Reno

Host: Colleen Clancy, Ph.D.

2013


January 15, 2013

Speaker: Robert Eisenberg (Rush Medical College, Illinois)

Host: Donald Bers, Ph.D.


February 11, 2013

Speaker: Paul Simpson, (University of California, San Francisco)

Host: Donald Bers, Ph.D.


March 19, 2013

Lecture: "Specificity of the Beta adrenergic signaling in cardiac myocytes: role of phosphodiesterases" (PDF)

Speaker: Marco Conti, (University of California, San Francisco)

Host: Kevin Xiang, Ph.D.


March 26, 2013

Lecture: "Molecular basis of metabolic and mitogenic effects of insulin, insulin analogues and insulin-like growth factors" (PDF)

Speaker: Pierre De Meyts (Novo-Nordisk)

Host: Mary Horne, Ph.D.


April 16, 2013

Lecture: "Membrane-targeted approaches to rescuing neurons from death following hypoxia-ischemia" (PDF)

Speaker: Jeremy Marks, (University of Chicago)

Host: Florin Despa, Ph.D.


September 17, 2013

Speaker: Vikram Shakkottai, (University of Michigan)

Host: Heike Wulff, Ph.D.


October 15, 2013

Lecture: "Deciphering the Electrical ‘Cross-Talk’ Underlying A Role for Desmosomal Cell-Cell Junctions in Cardiac Muscle Biology and Disease" (PDF)

Speaker: Fara Sheikh, (UCSD)

Host: Y Chen-Izu, Ph.D.


December 10, 2013

Speaker: Joseph Wu, (Stanford University)

Host: Kevin Xiang, Ph.D.


2012


September 07, 2012

Speaker: Kent E Pinkerton (University of California, Davis)


September 21, 2012

Lecture: "Calcium channel modulation involves calmodulin on the move"

Speaker: David Yue (John Hopkins University)


October 19, 2012

Lecture: "Control of intracellular Ca2+ in skeletal muscle--inside and outside"

Speaker: Paul D. Allen (University of California at Davis)


November 09, 2012

Speaker: Alessandra Renieri (University of Siena, Italy)


November 29, 2012

Lecture: "G ABA Receptor Games and Pesticide Puzzles"

Speaker: John E. Casida (Emeriti Professor of Department of Environmental Science, Policy, and Management, University of California, Berkeley)

Sponsored by: The UC Davis CounterAct Center for Excellence, Pharmacology Training Grant and Department of Pharmacology


December 07, 2012

Speaker: Virginia Brooks (Oregon Health Sciences University)


2011


January 14, 2011

Lecture: "Ion channel modulation: structure, function, and unconventional approaches"

Speaker: Dan Minor, UC San Francisco


February 4, 2011

Lecture: "Leukocyte guidance is signaled via B2-integrin and Orai1 durin inflammatory recruitment"

Speaker: Scott I. Simon, UC Davis, BME


February 18, 2011

Lecture: "Dynamics of Signaling by PKA"

Speaker: Susan Taylor, UC San Diego


March 29, 2011

Lecture: "Novel Molecular Mechanisms Linking the Metabolic Syndrome with Cardiovascular Dysfunction"

Speaker: E. Dale Abel, University of Iowa


April 8, 2011

Lecture: "Slowing the Ticking Clock: Using C. elegans to Discover Mechanisms Regulating Cognitive Aging Decline and Reproductive Cessation"

Speaker: Coleen Murphy, Princeton University


April 15, 2011

Lecture: "Natural epoxy-fatty acids and soluble epoxide hydrolase: Emerging therapeutic targets for neurological disorders"

Speaker: A. Bora Inceoglu, UC Davis


May 20, 2011

Lecture: TBD

Speaker: Stefan Strack, University of Iowa


2010


January 22, 2010

Lecture: "Role of Thrombin Activatable Fibrinolysis Inhibitor (TAFI)" (PDF)

Speaker: John Morser, Ph.D., Stanford School of Medicine


February 26, 2010

Lecture: "Regulation of sodium-activated potassium channels and the Fragile X Mental Retardation Protein signaling pathway" (PDF)

Speaker: Leonard Kaczmarek, Ph.D., Yale University


April 23, 2010

Lecture: "Calcium signaling defects in autoimmunity: the ion channel viewpoint" (PDF)

Speaker: Laura Conforti, Ph.D., University of Cincinnati


May 28, 2010

Lecture: "Natural Inequalities: Why Some L-type Calcium Channels Work Harder than Others" (PDF)

Speaker: Fernando Santana, Ph.D., University of Washington


June 1, 2010

Lecture: "Signaling Through Protein Kinases To Gene Expression In The Cardio Myocyte" (PDF)

Speaker: Peter Sugden, Ph.D., Angela Clerk, Ph.D. Imperial College, London


June 2, 2010

Lecture: "Central neural circuits and synapse"

Speaker: J. Julius Zhu, Ph.D., University of Virginia


September 10, 2010

Lecture: "Structural Mechanisms of Protein Kinase Regulation"

Speaker: John Kuriyan, UC Berkeley


November 12, 2010

Lecture: "High resolution of imaging of NMDA receptors? Learning from a single molecule!"

Speaker: Laurent Groc, Universite Bordeaux, France


November 18, 2010

Lecture: "Molecular mechanisms of hippocampal synaptic plasticity"

Speaker: Yasunori Hayashi, Brain Science Institute, Japan


December 3, 2010

Lecture: "The role of TNFalpha in synaptic plasticity and nervous system function"

Speaker: David Stellwagen, McGill University, Canada

2009


October 23, 2009

Lecture: "Translational concepts in drug discovery: Redesigning IMATINIB into a safer drug and taking it back to the clinic" (PDF)

Speaker: Ariel Fernandez, Ph.D., Rice University


November 13, 2009

Lecture: "Awake the sleeping, mute the sleeping: towards targeted overwriting of epigenetic marks to moculate gene expression profiles" (PDF)

Speaker: Mariann Rots, Ph.D., University of Groningen


December 4, 2009

Lecture: "Translating Soluble Epoxide Hydrolase Inhibitors into the Clinic, Picking the Right Target" (PDF)

Speaker: Bruce Hammock, Ph.D., UC Davis


2008


February 29, 2008

Lecture: Regulation and function of the K channel KCa3.1: Role in T cell activation and polycystic kidney disease. (PDF)

Speaker: Edward Skolnik, Ph.D., New York University Medical Center


March 14, 2008

Lecture: The Secret Lives of Calcium Channels (PDF)

Speaker: Ricardo Dolmetsch, Ph.D., Stanford University


2007


January 26, 2007

Lecture: CRACking the Molecular Components of Store-Operated Calcium Entry (PDF)

Speaker: Reinhold Penner, M.D., Ph.D., University of Hawaii at Manoa


March 2, 2007

Lecture: Triglyceride-Rich Lipoproteins: Friend or Foe? (PDF)

Speaker: John Rutledge, M.D., University of California, Davis


March 23, 2007

Lecture: Development of Light-Gated Ion Channels (PDF)

Speaker: Dirk Trauner, Ph.D., LMU Munich


April 20, 2007

Lecture: The Wonderful World of Zinc Finger Domains (PDF)

Speaker: Joel Mackay, Ph.D., School of Molecular and Microbial Biosciences, University of Sydney


May 11, 2007

Lecture: Intrinsic and Extrinsic Determinants of Ion Channel Clustering in Neurons (PDF)

Speaker: Matt Rasband, Ph.D., Baylor College of Medicine


June 22, 2007

Lecture: The Inflamed CNS as a Neo-Lymphoid Organ - Implications for Specific Immunotherapy of MS (PDF)

Speaker: Stephen D. Miller, Ph.D., Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University


September 28, 2007

Lecture: "Stem Cell Medicine: Building the Comprehensive Plan" (PDF)

Speaker: Mark Noble, Ph.D., University of Rochester


October 26, 2007

Lecture: "Using FRET to measure the binding affinity, binding kinetics, and structure of membrane protein complexes: Application to phospholamban and the cardiac calcium pump" (PDF)

Speaker: Seth L. Robia, Ph.D., Loyola University Chicago


November 30, 2007

Lecture: The intimate but controversial relationship between proton channels and the phagocyte NADPH oxidase (PDF)

Speaker: Thomas DeCoursey, Ph.D., Rush University Medical Center


December 14, 2007

Lecture: Can a Voltage Sensor also be a Gate? (PDF)

Speaker: Ehud Isacoff, Ph.D., UC Berkeley


2006


January 20, 2006

Lecture: "Killing Pain with Killer Snails: PRIALT, a Calcium Channel Blocking Analgesic from Marine Snail Venom"

Speaker: George Miljanich, Ph.D., Elan Pharmaceuticals


February 17, 2006

Lecture: "Structure and Functional Mechanisms of Voltage-gated K+ Channels"

Speaker: Robert Guy, M.D., Ph.D., NCI, National Institute of Health


March 17, 2006

Lecture: "Proteomic Characterization of the Murine Cardiac 26S Proteasome Complexes"

Speaker: Piepei Ping, Ph.D., University of California, Los Angeles


June 16, 2006

Lecture: "Reprogrammin tumor cells with artificial transcription factors"

Speaker: Pilar Blancafort, Ph.D., University of North Carolina at Chapel Hill


June 30, 2006

Lecture: "Ryanodine receptors, chief integrators of cellular calcium signals at the cutting edge of health and disease"

Speaker: Isaac Pessah, Ph.D., University of California, Davis


October 13, 2006

Lecture: "The Dynamic Dyad: A Mechanism for Store-Operated Calcium Signaling" (PDF)

Speaker: Richard Lewis, Ph.D., Stanford Medical School


November 2, 2006

Lecture: "Coupling of Cav and BKCa Channels Analyzed by Functional Proteomics" (PDF)

Speaker: Bernd Fakler, M.D., University of Freiburg


2005


January 13, 2005

Lecture: "Intracellular Signaling From the Endoplasmic Reticulum to the Nucleus"

Speaker: Peter Walter, Ph.D., University of California, San Francisco


February 11, 2005

Lecture: "Novel Potassium Channels Revealed by the Comparative Genomic Approach"

Speaker: Lawrence B. Salkoff, Ph.D., Washington University, School of Medicine


March 11, 2005

Lecture: "Ion Channel Mutations in Human Disease: Insights into Novel Cellular Physiology and Pharmacology"

Speaker: Robert S. Kass, Ph.D., Columbia University, School of Medicine


April 8, 2005

Lecture: "Ion Channels and Behavior: Sleep Loss and Motor Dysfunction in Kv3-deficient Mice"

Speaker: Ralph H. Joho, Ph.D., The University of Texas Southwestern Medical Center at Dallas


April 22, 2005

Lecture: "Cell-Based Cardiac and Vascular Repair: What Does the Future Hold?"

Speaker: Doris A. Taylor, Ph.D., University of Minnesota School of Medicine


May 20, 2005

Lecture: "Learning From the Pupils: Lessons in Non-visual Ocular Photoreception"

Speaker: Russell N. Van Gelder, M.D., Ph.D., Washington University School of Medicine


June 3, 2005

Lecture: "Rapid and Ultrasensitive Detection of Pathogens Using Single Molecule Analysis with Quantum Dots: Applications in Biodefense and Clinical Diagnostics"

Speaker: Dan Shoemaker, Ph.D., GHC Technologies, Inc


September 23, 2005

Lecture: "Bugs, Drugs and Microarrays: Genomic Approaches to Infectious Disease"

Speaker: Joe DeRisi, Ph.D., University of California, San Francisco


October 21, 2005

Lecture: "Degenerative Ataxias: From Polyglutamine Proteins and Ion Channels"

Speaker: Stefan Pulst, M.D., UCLA School of Medicine


November 18, 2005

Lecture: "Chemical Regulation of Gene Expression"

Speaker: Joel Gottesfeld, Ph.D., Scripps Research Institute


December 9, 2005

Lecture: "Targeting potassium channels for therapy of autoimmunity, ataxia and atherosclerosis"

Speaker: George Chandy, M.D., Ph.D., University of California, Irvine