Alaa Afify, M.D.


Director of Cytopathology

Department of Pathology and Laboratory Medicine
UC Davis Medical Center
PATH Building
4400 V Street
Sacramento, CA 95817

Ph: (916)734-7477
Pager: (916) 762-5981

Clinical Interests

  • Cytopathology
  • Surgical pathology


Research Interests

The interaction between normal cells and their surrounding environment is important in maintaining tissue organization, controlling proliferation, and regulating cell motility. This is accomplished through the existence of a number of transmembrane receptors that interact with stromal extracellular molecules. One of these receptors, CD44, binds to the extracellular matrix component, hyaluronan. Dr. Afify’s major research area of interest is in studying hyaluronan and CD44 and their role in cancer.


Brief Biography

Dr. Afify completed an internship at Woodhull Medical & Mental Health Center in New York City in internal medicine. After completing his residency training in Pathology at Brown University School of Medicine in Rhode Island from 1992-1996, he completed a fellowship in Oncologic Surgical Pathology at the Roswell Park Cancer Institute in Buffalo, New York. Following his Oncologic Surgical Pathology fellowship, Dr. Afify completed a second fellowship in Cytopathology at Washington University School of Medicine in St. Louis, Missouri. Dr. Afify is board certified in Anatomic/clinical pathology and he also board certified in Cytopathology. He joined the University of Michigan, Department of Pathology as an Assistant Professor of Pathology from 1998-2002 where he also served as the Director of Immunohistochemistry. Since 2002, Dr. Afify has been a member of the Department of Pathology and Laboratory Medicine at UC Davis and currently serves as the Director of Cytopathology for the department and Director of Cytopathology Training Program.

Dr. Afify is a member of the American Society of Cytopathology, the College of American Pathologists and the United States and Canadian Academy of Pathology.


Representative Publications

Recent publications listed in PubMed