Pamela J. Lein, Ph.D.
Professor, Department of Molecular Biosciences, School of Veterinary Medicine; Chair, UC Davis Pharmacology and Toxicology Graduate Group
1089 Veterinary Medicine Dr. (VM3B)
Dr. Lein is a developmental neurobiologist with research interested in the molecular and cellular mechanisms by which environmental stressors modulate neurodevelopment. Her current research focuses on: (1) interactions between genetic alterations in ryanodine receptors and environmental factors that modulate calcium signaling that alter normal patterns of neuronal connectivity in the developing brain; (2) novel biomarkers and medical countermeasures for organophosphorus anticholinesterase-induced neurotoxicity; and (3) the influence of neuroimmune interactions on neuronal morphogenesis and synapse formation. The ultimate goal this research is to identify environmental stressors that can be readily controlled to decrease the incidence and/or severity of neurodevelopmental disorders. Dr. Lein has developed a well-funded, collaborative and interdisciplinary research program with colleagues across the university, as well as nationally and internationally. She is the Chair of the Graduate Group in Pharmacology and Toxicology at UC Davis, and a member of the MIND Institute.
B.S., Biological Sciences, Cornell University, 1981
M.S., Environmental Health, East Tennessee State University, 1983
Ph.D., Pharmacology and Toxicology, State University of New York, Buffalo
Dr. Lein's publications and academic activities (PDF)