Richard Tucker, Ph.D.
3414 Tupper Hall
Dr. Tucker’s laboratory studies cell-cell and cell-extracellular matrix interactions, especially how they relate to cell motility and differentiation. He also studies the evolution of extracellular matrix and cell-cell adhesion molecules. Model systems used include the development of the avian visual system, tumor metastasis, stem cell niches and growth and regeneration in the marine invertebrate Nematostella. Most of his work focuses on the roles of tenascins, thrombospondins and teneurins. Tenascins and thrombospondins are extracellular matrix glycoproteins that can influence cell motility, proliferation and differentiation in the embryo. They often reappear in tumors and at sites of trauma. Teneurins are transmembrane glycoproteins expressed by interconnected populations of neurons. Recent evidence suggests that teneurins evolved via horizontal gene transfer between a choanoflagellate and prokaryotic prey.
2016 Midwood, K., M. Chiquet, R.P. Tucker and G. Orend. Tenascin-C at a glance. Journal of Cell Science 129:4321-4327.
2016 Tucker, R.P., C.A. Peterson, I. Hendaoui, S. Bichet and R. Chiquet-Ehrismann. The expression of tenascin-C and tenascin-W in human ossicles. Journal of Anatomy 229:416-421.
2015 Tucker, R.P. and R. Chiquet-Ehrismann. Tenascin-C: Its functions as an integrin ligand. International Journal of Biochemistry and Cell Biology 65:165-168.
2014 Tucker, R.P. and J.C. Adams. Adhesion networks of cnidarians: A post-genomic view. International Review of Cell and Molecular Biology 308:323-377.
2014 Chiquet-Ehrismann, R., G. Orend, M. Chiquet, R.P. Tucker and K.S. Midwood. Tenascins in stem cell niches. Matrix Biology 37:112-123. (cover photo)
2014 Hendaoui, I., R.P. Tucker, D. Zingg, S. Bichet, J. Schittny and R. Chiquet-Ehrismann. Tenascin-C is required for normal Wnt/β-catenin signaling in the whisker follicle stem cell niche. Matrix Biology 40:46-53.
2014 Gong, Q., K. Garvey, C. Qian, I. Yin, G. Wong and R.P. Tucker. The integrins of the starlet sea anemone Nematostella vectensis. Biological Bulletin 227:211-220.
2014 Adams, J.C., R. Chiquet-Ehrismann and R.P. Tucker. The evolution of tenascins and fibronectin. Cell Adhesion and Migration 9:1-12.
2013 Peterson, C.A., C.A. Wacker, T.L. Phelan, A.K. Blume and R.P. Tucker. Anatomical differences in the shape of the male and female carpal tunnels. Journal of Women’s Health Physical Therapy 37:108-112.
2013 Tucker, R.P. and Q. Gong. Chapter 15: Immunohistochemistry and in situ hybridization in the developing chicken brain. In: Brain Development: Methods and Protocols,S.G. Sprecher (ed.) Methods in Molecular Biology, Vol. 1082, pp. 217-233.
2013 Tucker, R.P., J. Ferralli, J.C. Schittny and R. Chiquet-Ehrismann. Tenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration. Journal of Cell Science 126:5111-5115. (cover photo)
2013 Tucker, R.P., J.F. Hess, Q. Gong, K. Garvey, B. Shibata and J.C. Adams. A thrombospondin in the anthozoan Nematostella vectensis is associated with the nervous system and upregulated during regeneration. Biology Open 2:217-226.
2013 Dranow, D.B., R.P. Tucker and B.W. Draper. Germ cells are required to maintain a stable sexual phenotype. Developmental Biology, Jan 21. [e-pub ahead of print] (“Faculty of 1000 Recommended”)
2013 Tucker, R.P. Horizontal gene transfer in choanoflagellates. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 320:1-9.
2012 Tucker, R.P., J. Beckmann, N.T. Leachman, J. Schöler and R. Chiquet-Ehrismann. Phylogenetic analysis of the teneurins: conserved features and premetazoan ancestry. Molecular Biology and Evolution 29:1019-1029.
2012 Brellier, F., E. Martina, M. Chiquet, J. Ferralli, M. van der Heyden, G. Orend, J.C. Schittny, R. Chiquet-Ehrismann and R.P. Tucker. The adhesion modulating properties of tenascin-W. International Journal of Biological Sciences 8:187-194.
2012 Chiquet-Ehrismann, R. and R.P. Tucker. Tenascins and the importance of adhesion modulation. In: Cold Spring Harbor Perspective in Biology: Extracellular Matrix Biology, R.O. Hynes and K. Yamada (eds.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. pp. 129-147.
- CHA 400, Developmental, Gross and Radiographic Anatomy (Course Director)
- CHA 402, Cell and Tissue Biology
- CHA 200, Graduate Human Gross Anatomy (Course Co-Director)
- BCB 213, Developmental Biology (Course Director)
- Davis Division Academic Senate Graduate/Professional School Distinguished Teaching Award 2012
- Kaiser Foundation Annual Award for Excellence in Teaching Basic Sciences, 1998, 2002, 2007, 2012
- Biochemistry and Molecular, Cellular and Developmental Biology Graduate Group Teaching Award, 2011, 2014
- UC Davis School of Medicine, Outstanding Basic Science Instructor, 2002, 2003, 2004, 2008, 2014
- UC Davis School of Medicine, Tupper Prize for Excellence in Teaching, 2007
- UC Davis School of Medicine, Excellence in Education Award, 2005
- Gian Toendury Prize for the Promotion of Research in Morphological Sciences, 1989
- National Science Foundation