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UC Davis Health System

UC Davis Health System

UC Davis study links smoking with most male cancer deaths

man lighting cigarette
The study authors concluded that the very close relationship over twenty-five years between lung and other cancer death rates suggests a single cause for both: tobacco smoke.

The association between tobacco smoke and cancer deaths — beyond lung cancer deaths — has been strengthened by a recent study from a UC Davis researcher, suggesting that increased tobacco control efforts could save more lives than previously estimated.

The epidemiological analysis, published online in BMC Cancer, linked smoking to more than 70 percent of the cancer death burden among Massachusetts men in 2003. This percentage is much higher than the previous estimate of 34 percent in 2001.

"This study provides support for the growing understanding among researchers that smoking is a cause of many more cancer deaths besides lung cancer," said lead author Bruce Leistikow, a UC Davis associate adjunct professor of public health sciences. "The full impacts of tobacco smoke, including secondhand smoke, have been overlooked in the rush to examine such potential cancer factors as diet and environmental contaminants. As it turns out, much of the answer was probably smoking all along."

Leistikow used National Center for Health Statistics data to compare death rates from lung cancer to death rates from all other cancers among Massachusetts males.

The assessment revealed that the two rates changed in tandem year-by-year from 1979 to 2003, with the strongest association among males aged 30-to-74 years.

Bruce Leistikow "The full impacts of tobacco smoke, including secondhand smoke, have been overlooked in the rush to examine such potential cancer factors as diet and environmental contaminants. As it turns out, much of the answer was probably smoking all along."
— Bruce Leistikow, study lead author

Smoking is a known cause of most lung cancers, and the study authors concluded that the very close relationship over twenty-five years between lung and other cancer death rates suggests a single cause for both: tobacco smoke.

Leistikow, whose research is dedicated to uncovering the causes of premature mortality, said, "The fact that lung and non-lung cancer death rates are almost perfectly associated means that smokers and nonsmokers alike should do what they can to avoid tobacco smoke. It also suggests that increased attention should be paid to smoking prevention in health care reforms and health promotion campaigns."

The current study, which was funded by UC Davis, the Health Research Board (Ireland) and the National Cancer Institute, can be downloaded at www.biomedcentral.com/1471-2407/8/341.

Coauthors of the study were Zubair Kabir of the Harvard School of Public Health and the Research Institute for a Tobacco-Free Society (Ireland), Gregory Connolly and Hillel R. Alpert of the Harvard School of Public Health and Luke Clancy of the Research Institute for a Tobacco-Free Society.

Smoking cessation support is available from the helpline (800) QUIT NOW. Additional sources of help include www.smokefree.gov, the American Cancer Society at (800) 227-2345, the American Lung Association at (800) 586-4872 and the National Cancer Institute at (800) 422-6237.