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Department of Urology

Department of Urology

Clinical Research in the Department of Urology



PERSPECTIVE: A Prospective, Non-Interventional, Registry Study of Patients Initiating a Course of Drug Therapy of Overactive Bladder (OAB)

Description of Research Study: To identify factors associated with improved effectiveness in pharmacologic therapy of OAB from the patient perspective. As well as to compare persistence rates, reasons for discontinuation, and switching patterns among patients taking mirabegron compared to those taking antimuscarinic treatments for OAB and to understand how differences in drug selection, duration of OAB diagnosis, prior therapies, co-morbid conditions, and adjunctive non-pharmacologic therapy contribute to OAB outcomes in the real world.
Principal Investigator: Jennifer Rothschild, M.D., Department of Urology
Co-Investigator: Marc Dall'Era, M.D., Department of Urology
Research Coordinator: Rebecca M. Rankin Wagenaar, M.S., CCRC,  Department of Urology

 
Pre-Treatment Counseling and Education for Urological Malignancy Patients

Description of Research Study: To improve quality of care by educating patients prior to treatment on the outcomes they can expect post treatment, the Department of Urology is inviting patients planning definitive management of prostate cancer with radiation therapy or surgical prostatectomy to participate in this study which will evaluate the benefit of expanded pre-treatment counseling and education.
Principal Investigator: Marc Dall'Era, M.D., Department of Urology
Co-Investigator: Christopher P. Evans, M.D., F.A.C.S.  Departments of Urology
Research Coordinator: Rebecca M. Rankin Wagenaar, M.S., CCRC,  Department of Urology


Radiologically Guided Biopsies of Metastatic Castration Resistant Prostate Cancer to Identify Adaptive Mechanisms of Resistance

Description of Research Study: The purpose of this study is to better understand how cancer treatment may affect cancer cells in patients with castrate-resistant prostate cancer (CRPC) that either recurred or did not respond to treatment. It is hoped that the information gained from these studies will lead to a greater understanding of castrate-resistant prostate cancer and potentially, improvements in cancer treatment.
Principal Investigator: Christopher P. Evans, M.D., F.A.C.S., Department of Urology
Co-Investigator: Primo Lara, M.D.  Department of Internal Medicine, Division of Hematology Oncology
Research Coordinator: Rebecca M. Rankin Wagenaar, M.S., CCRC,  Department of Urology


Survey of Peyronie's Prevalence in Dupuytren’s Disease Patients

Description of Research Study: In hopes to improve men's health we are conducting a survey research project on men with nodules and/or cords in the hand, a condition called Dupuytren's disease, and to better understand the prevalence of Peyronie's disease. Our goal is to increase awareness of this comorbidity in hopes that it may facilitate prompt referral for treatment and improve patient quality of life.
Principal Investigator:  Jennifer Rothschild, M.D., Department of Urology
Co-Investigator: Robert Szabo, M.D., Department of Orthopaedics
Research Coordinator: Rebecca M. Rankin Wagenaar, M.S., CCRC,  Department of Urology


Pictoral Scale of Bladder Urgency

Description of Research Study: We are studying a way to help children tell their doctors how they feel when they have to go to the bathroom.
Principal Investigator: Eric Kurzrock, M.D., F.A.A.P., Department of Urology
Co-Investigator: Paula Wagner, F-N.P., Department of Urology
Research Coordinator: Rebecca M. Rankin Wagenaar, M.S., CCRC,  Department of Urology


Pictoral Scale of Bladder Fullness and Bladder Volume During Voiding Cystgraphy

Description of Research Study: We are studying a way to help children tell their doctors how they feel when they have to go to the bathroom.
Principal Investigator: Eric Kurzrock, M.D., F.A.A.P., Department of Urology
Co-Investigator: Paula Wagner, F-N.P., Department of Urology
Research Coordinator: Rebecca M. Rankin Wagenaar, M.S., CCRC,  Department of Urology


EMBARK, MCV3100-13, A Phase 3, Randomized, Efficacy and Safety Study of Enzalutamide Plus Leuprolide, Enzalutamide Monotherapy, and Placebo Plus Leuprolide in Men With High-Risk Nonmetastatic Prostate Cancer Progressing After Definitive Therapy

Description of Research Study: To evaluate efficacy of enzalutamide plus leuprolide compared to enzalutamide monotherapy and placebo plus leuprolide, as measured by metastasis-free survival and overall survival.
Principal Investigator: Christopher P. Evans, M.D., F.A.C.S., Department of Urology
Co-Investigator: Primo Lara, M.D., Department of Internal Medicine, Division of Hematology Oncology
Research Coordinator: Clinical Trials Support Unit (CTSU)