Chromosomal anomaly in Fragile X gene carriers
Male carriers of fragile X syndrome have chromosomes shortened at the tips compared to men their own age, a UC Davis M.I.N.D. Institute study has found. The finding may help to explain why these carriers sometimes develop fragile X-associated tremor/ataxia syndrome (FXTAS) that causes tremor and balance problems in addition to Alzheimer's like symptoms later in life, said one of the study's authors, Randi Hagerman, medical director and endowed chair of fragile X research at the M.I.N.D. Institute. The study was published in the American Journal of Medical Genetics Part A.