For the first time, UC Davis and Mount Sinai School of Medicine scientists have captured video footage showing the transfer of the human immunodeficiency virus (HIV) from an infected T-cell to an uninfected one through an adhesive structure called a virological synapse. The researchers say their breakthrough finding, which appeared in Science, may lead to new HIV treatments and revive efforts to develop a vaccine. The video images were produced using advanced, live-cell video imaging microscopy at the UC Davis Center for Biophotonics Science and Technology under the direction of chief scientist Thomas Huser, one of the study's authors.