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"" Ann Bonham named acting executive associate dean ""
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"" Traditional test for predicting heart disease found unreliable ""
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"" Ophthalmologist receives grant to study bioengineered material ""
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  Immune, protein alterations found in blood samples of children with autism  
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  Brain region recovery possible in former methamphetamine users  
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  CT technology may be gentler, more accurate than mammography  
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  Town raises $1 million to fight cancer  
     
  Researchers discover new link between C-reactive protein and heart disease, stroke  
     
  UC Davis study on drug advertising shows influence on physicians  
     
  Study shows women not using tamoxifen for cancer prevention  
     
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Study shows women not using tamoxifen for cancer prevention

Among women at high risk for breast cancer, fewer than one in five were inclined to take the drug tamoxifen to prevent the disease, according to UC Davis Health System researchers. Concerns about the drug's potential side effects were the primary reason. The study, funded by the California Breast Cancer Research Program and the National Cancer Institute, was published in CANCER, a peer-reviewed journal of the American Cancer Society.

Taking tamoxifen can reduce a woman's risk of developing breast cancer by as much as 49 percent. However, the drug increases risks for endometrial cancer, deep venous thrombosis, pulmonary embolism, painful sexual intercourse and cataracts requiring surgery.

Joy Melnikow, UC Davis family and community medicine professor and the study's lead author, said, "Women in our study were very concerned about potential harmful effects when they considered taking tamoxifen to reduce their risk for a disease they might not get."

The finding has implications for the development of other chemoprevention drugs to reduce cancer risk.

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