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UC Davis Medicine Logo
The institution's principal publication for alumni, friends and physicians.
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  N E W S  
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"" Mechanism for attentional control found ""
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"" Grant for FNP/PA program ""
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  Cancer center network launched  
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  Unusual toy use is autism clue  
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  Key to aggressive breast cancer found  
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  Environmental reasons for dating violence  
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  Clue to unexplained deaths of epilepsy patients  
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  Gates Foundation funds TB study  
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  New telemedicine equipment loan program  
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  Another antibiotic-overuse consequence  
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  Molecule targeting brain tumors found  
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  Reducing potential nerve damage  
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  Starving pancreatic cancer cells  
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  New IQ scoring for children with intellectual disabilities  
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  UC Davis discovery offers hope for treating kidney cancer  
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Diet cuts return of breast cancer in women without hot flashes

 
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  Grant funds breast-cancer vaccine study  
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  Nesbitt to help direct state telehealth services  
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  Stem cell research collaboration  
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NEWS
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UC Davis discovery offers hope for treating kidney cancer

In one of the first discoveries of its kind, UC Davis Cancer Center researchers have identified ways to block a cancer gene's own repair mechanism and, in so doing, help make chemotherapy for kidney cancer more effective and better tolerated. Robert Weiss, UC Davis professor of nephrology and chief of nephrology at the Sacramento VA Medical Center, and his team identified compounds that could interrupt the pathway of the p21 gene. The gene has an important role in restoring cancer cell DNA and potentially circumventing benefits of traditional treatments. Three of the 12 compounds found to bind to p21 specifically blocked kidney cancer cells' ability to mend and thereby made them more responsive to cancer DNA-damaging treatments. The outcome is published in Cancer Biology and Therapy.

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UC DAVIS SCHOOL OF MEDICINE
PUBLIC AFFAIRS
4900 Broadway, Suite #1200
Sacramento, CA 95820

© 2009 UC Regents. All rights reserved.

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