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UC Davis Medicine Logo
The institution's principal publication for alumni, friends and physicians.
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  N E W S  
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"" Mechanism for attentional control found ""
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"" Grant for FNP/PA program ""
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  Cancer center network launched  
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  Unusual toy use is autism clue  
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  Key to aggressive breast cancer found  
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  Environmental reasons for dating violence  
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  Clue to unexplained deaths of epilepsy patients  
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  Gates Foundation funds TB study  
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  New telemedicine equipment loan program  
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  Another antibiotic-overuse consequence  
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  Molecule targeting brain tumors found  
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  Reducing potential nerve damage  
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  Starving pancreatic cancer cells  
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  New IQ scoring for children with intellectual disabilities  
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  UC Davis discovery offers hope for treating kidney cancer  
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Diet cuts return of breast cancer in women without hot flashes

 
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  Grant funds breast-cancer vaccine study  
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  Nesbitt to help direct state telehealth services  
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  Stem cell research collaboration  
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NEWS
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Starving pancreatic cancer cells

A UC Davis Cancer Center study published in the International Journal of Cancer indicates that pancreatic cancer cells cannot produce the amino acid arginine, which plays an essential role in cell division, immune function and hormone regulation. By depleting arginine levels in cell cultures and animal models, the team was able to significantly reduce pancreatic cancer-cell proliferation. Led by Richard Bold, chief of surgical oncology, researchers found that exposing pancreatic cancer cells to a modified arginine deiminase enzyme inhibited cancercell proliferation by 50 percent. According to Bold, the study represents a unique approach to cancer treatment in that it is one of the first to identify a metabolic pathway that can be leveraged to interrupt cancer growth.

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UC DAVIS SCHOOL OF MEDICINE
PUBLIC AFFAIRS
4900 Broadway, Suite #1200
Sacramento, CA 95820

© 2009 UC Regents. All rights reserved.

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