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UC Davis Medicine Logo
The institution's principal publication for alumni, friends and physicians.
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  N E W S  
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"" New avenue for drug development ""
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"" Statins help with heart disease, diabetes ""
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"" New education building opens to students, uniting all four years under one roof ""
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  Rue plant source of new arthritis, diabetes drugs  
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  HIV hides from drugs in gut  
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  OJ drink cuts heart disease risk  
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  Biotechnology pacemakers closer to replacing electronic versions  
     
  NIH funds new center for clinical, translational research  
     
  Vascular surgery broadcast  
     
  NIH grants up  
     
  New associate dean  
     
  New chair for orthopaedic surgery  
     
  New CEO for medical center  
     
  Stereotypes keep men from seeking help  
     
  Better snacks have impact  
     
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NEWS
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HIV hides from drugs in gut

UC Davis researchers have discovered that the HIV virus is able to survive efforts to destroy it by hiding out in the mucosal tissues of the intestine. In a study led by Satya Dandekar, professor and chair of the Department of Medical Microbiology and Immunology at UC Davis, researchers also found that HIV continues to replicate in the gut mucosa, suppressing immune function in patients being treated with antiretroviral therapy, even when blood samples from the same individuals indicated the treatment was working.

Results of the three-year study, which appeared in the Journal of Virology, suggest that patients being treated with antiretroviral therapy should be monitored using gut biopsies and that the gut's immune function be restored through earlier antiretroviral treatment and the use of antiinflammatory medications.

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UC DAVIS SCHOOL OF MEDICINE
PUBLIC AFFAIRS
4900 Broadway, Suite #1200
Sacramento, CA 95820

ucdavismedicine@ucdmc.ucdavis.edu

© 2007 UC Regents. All Rights Reserved.

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