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UC Davis Medicine - Logo
The institution's principal publication for alumni, friends and physicians.
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  N E W S  
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"" New Park Honoring Cancer Survivors Opens ""
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"" Increase in Autism Cases is Real, Report Finds ""
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  Breastfeeding Boosts Baby's Resistance to Respiratory Illnesses  
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  Grant Supports Rural Areas in Helping Children with Autism  
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  Study Shows Syringe-Exchange Reduces HIV Risk Behavior  
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  Consumers: UC Davis Medical Center has Highest Quality in Sacramento  
     
  Handgun Study to Fortify Crime Prevention Efforts  
     
  UC Medical Center Ranks Among Country's Top 50 Hospitals  
     
  Unique Program Aims to Get Pediatricians into Communities  
     
  New Predictor of Heart Disease Risk Causes Vessel Damage, Plaque Formation  
     
  Center for Perinatal Medicine and Law Established  
     
  UC Davis Study Identifies Promising Epilepsy Treatment  
     
  UC Davis Study Finds Eye Drops Delay Onset of Glaucoma  
     
  M.I.N.D. Institute Seeks Diagnostic Test for Autism  
     
  New Chair of Microbiology, Immunology Named  
     
  Career Satisfaction Varies by Specialty, Geographic Region  
     
  New Chair of Biological Chemistry Appointed  
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Summer 2003 Issue
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NEWS
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NEW PREDICTOR OF HEART DISEASE RISK CAUSES VESSEL DAMAGE, PLAQUE FORMATION

UC Davis physicians have discovered that a new predictor of heart disease risk, c-reactive protein, also damages blood vessel walls by blocking a critical "protector" protein and by promoting plaque formation.

The finding, published recently in the journal Circulation, describes a new molecular pathway that stimulates plaque formation. The work provides a new target for drug development efforts, explains why cholesterol screening is not enough to accurately assess heart disease risk, and underscores the need to use c-reactive protein screening.

The researchers found that c-reactive protein inhibits the activity of an enzyme in the blood vessel wall that works to keep blood vessels healthy and heart disease at bay by preventing plaques from adhering to blood vessel walls.

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UC DAVIS SCHOOL OF MEDICINE
PUBLIC AFFAIRS
4900 Broadway, Suite1200
Sacramento, California 95820

ucdavismedicine@ucdmc.ucdavis.edu

© 2003 UC Regents. All rights reserved.

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