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UC Davis Medicine Logo
The institution's principal publication for alumni, friends and physicians.
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  N E W S  
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"" Pediatric ER research work renewed ""
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"" Colon cancer screening less likely for minorities ""
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"" Commentary in JAMA on spirituality's role in medical care ""
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  Managing chronic disease drug costs  
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  Ketones may be culprits in some diabetics' heart problems  
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  Adult bladder stem cells identified  
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  New director of student diversity  
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  When to send sick children to specialty hospitals  
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  Study shows safety of adult stem-cell therapy  
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  New pharmacology department chair  
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  New wide-field light microscope  
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  Treating neonatal diabetes with oral medication  
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  High marks for conflict-of-interest policies  
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  Some follow-up breast cancer surgeries eliminated  
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NEWS
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Managing chronic disease drug costs

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Professor Richard Kravitz and his research team have concluded that an alternative method for determining the best drug therapy for managing chronic disease could reduce treatment costs or give patients more immediate relief than other common approaches typically approved for use by managed care and health insurance companies. The study, entitled "N-of-1 Trials of Expensive Biological Therapies — A Third Way," found that after evaluating three clinical strategies used to treat rheumatoid arthritis — stepped care, open access and an "n-of-1 trial" — the n-of-1 option was 47 percent cheaper than open access to the drugs, although it was 15 percent more expensive than stepped care. The study concluded that the n-of-1 approach may allow patients and their physicians to make more informed decisions about treatment selection because it tests a drug's efficacy earlier in process. The study was published online in the Archives of Internal Medicine.

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UC DAVIS SCHOOL OF MEDICINE
PUBLIC AFFAIRS
4900 Broadway, Suite #1200
Sacramento, CA 95820

© 2008 UC Regents. All Rights Reserved.

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