science through technology
you were looking for a blueprint of how genetic changes affect health,
you couldn't come up with a much better model than cancer.
mutations that occur during cell division - and which, down the
road, could lead to carcinogenesis - have implications for immunology,
microbiology, genetics, cellular biology, even veterinary medicine.
has a lot to teach us, because if you can learn how abnormal cells
react, by extrapolation, you can learn how normal ones react,"
says Regina Gandour-Edwards, a pathologist at UC Davis Medical Center.
"It's a powerful model."
link is one reason why Janine LaSalle, an assistant professor of
microbiology and immunology at UC Davis, finds herself studying
genetic mutations in human cancer. An immunonologist with a Ph.D.
from Harvard University, LaSalle began her research career with
a dual interest in genetics and immunology, focusing on pediatric
disorders. She was an instructor of pediatrics in the genetics division
of Children's Hospital at Harvard Medical School before coming to
the medical microbiology and immunology department at UC Davis in
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using cell-staining techniques in conjunction with laser-scanning
cytometry, UC Davis researchers hope to create a molecular staging
profile for bladder cancer.