Clinical/Research Interests

Dr. Martinez incorporates several novel techniques into his practice, including the use of the sentinel node biopsy for melanoma and breast cancer, skin-sparing mastectomy, onco-plastic lumpectomy for breast cancer, radio-guided parathyroidectomy, minimally invasive parathyroidectomy, minimally invasive thyroidectomy, and PET-probe guided resection of metastatic disease.

In addition to his clinical work, Dr. Martinez conducts research that incorporates his prior experience in molecular oncology with his interest in health care disparities, improving cancer care outcomes, and clinical trials. In particular, Dr. Martinez is interested in combining novel imaging techniques with blood-based biomarkers to predict response to pre-operative chemotherapy in patients with cancer.

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Select Recent Publications:

Sunami, E., M. Shinozaki, C.S. Higano, R. Wollman, T.B. Dorff, S. J. Tucker, S.R. Martinez, R. Mizuno, F. R. Singer, and D. Hoon. A Multimarker Circulating DNA Assay for Assessing Prostate Cancer Patients' Blood. Clinical Chemistry. 55(3):559-67, 2009.

Bowen SL, Wu Y, Chaudhari AJ, Fu L, Packard NJ, Burkett GW, Yang K, Lindfors KK, Shelton DK, Hagge R, Borowsky AD, Martinez SR, Qi J, Boone JM, Cherry SR, Badawi RD. Initial characterization of a dedicated breast PET/CT scanner during human imaging. Journal of Nuclear Medicine, 50(9):1401-1408.

Kitago M, Martinez SR, Nakamura T, Sim MS, Hoon DS. Regulation of RUNX3 tumor suppressor gene expression in cutaneous melanoma. Clinical Cancer Research, 15(9):2988-2994.

Martinez, S.R., R.J. Hagge, S.D. Christensen, J.M Webb. Metastatic breast cancer mimicking benign fatty liver infiltration. The Breast Journal, 14(1):108, 2008.

Martinez, S.R., A.S. Robbins, F.J. Myers, R.J. Bold, V.J. Khatri, J.E. Goodnight, Jr. Racial and ethnic differences in treatment and survival among adults with primary extremity soft tissue sarcoma. Cancer, 112(5):1162-1168, 2008.

Martinez, S.R., and S.E. Young. A rational surgical approach to the treatment of distant melanoma metastases. Cancer Treatment Review, 34(7):614-20, 2008.

Leggett, M.D., S.L. Chen, P.D. Schneider, S.R. Martinez Prognostic value of lymph node yield and metastatic lymph node ratio in medullary thyroid carcinoma. Annals of Surgical Oncology, 15(9):2493-9, 2008.

Chen, S.L., S.R. Martinez. The survival impact of the choice of surgical procedure after ipsilateral breast cancer recurrence. American Journal of Surgery, 196(4):495-9, 2008.

Nakagawa, T., S.R. Martinez, Y. Goto, K. Koyanagi, M. Kitago, T. Shingai, D.A. Elashoff, X. Ye, F.R. Singer, A.E. Giuliano, D.S.B. Hoon. Detection of circulating tumor cells in early-stage breast cancer metastasis to axillary lymph nodes. Clinical Cancer Research, 13(14):4105-4110, 2007.

Young SE, Martinez SR, Essner R. The role of surgery in the treatment of stage-IV melanoma. Journal of Surgical Oncology, 94:344-351, 2006