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UC Davis Health System

Richart William Harper, M.D.

Richart William Harper

Clinical/Research Interests

Dr. Harper diagnoses and manages patients with congenital or acquired lung diseases such as asthma, tuberculosis, primary pulmonary hypertension, interstitial lung disease and lung cancer. His research includes the study of oxidative stress in airway epithelial cells and the molecular basis mechanisms of lung cancer development. He is specifically examining signal transduction pathways in response to cigarette smoke. Harper also has a special interest in interstitial lung diseases, including sarcoidosis.

Title:

Associate Professor

Specialty:

Pulmonary and Critical Care

Address:

UC Davis Medical Group - Sacramento (J Street)
2825 J St., Suite 400
Sacramento, CA 95816

Education:

Georgetown University School of Medicine
Washington, D.C.
M.D. 1993

Residency:

UC Davis Medical Center
Sacramento, California
1993-1996
Internal Medicine

Fellowships:

UC Davis Medical Center
Sacramento, California
1996-1999
Pulmonary & Critical Care Medicine

Board Certifications:

American Board of Internal Medicine, Critical Care Medicine, 2001
American Board of Internal Medicine, Pulmonary Disease, 2000
American Board of Internal Medicine, 1996

Professional Memberships:

American Academy for the Advancement of Science
American College of Physicians
American Thoracic Society
Society of Critical Care Medicine

Select Recent Publications:

Yoneda, K.Y., R.W. Harper, and S. Louie. Severe obstructive pulmonary disease. Clinical Reviews in Allergy & Immunology 25:151-163, 2003.

Di, Y.P, R. Harper, Y. Zhao, N. Pahlavan, R. Wu. Molecular cloning and characterization of spurt, a human novel gene that is retinoic acid-inducible and encodes a secretory protein specific in upper respiratory tracts. Journal of Biological Chemistry 278(2):1165-1173, 2003.

Di W.H., S.P. Reddy, Y P. Di, K. Yoneda, R. Harper, R. Wu. Regulation of thioredoxin gene expression by vitamin A in human airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology 26(2):627-635, 2002.

Harper, R., K. Wu, M. M. J. Chang, K. Yoneda, R. Pan, S. P.-M Reddy, and R. Wu. Activation of nuclear factor-ęB transcriptional activity in airway epithelial cells by thioredoxin but not by N-acetyl-cysteine and gluthathione. American Journal of Respiratory Cell and Molecular Biology 25:178-185. 2001

Harper R. W., Louie S, Albertson TE, Tharratt RS. The case of the tattooed assault victim. Bronchoscopy Clinic. Journal of Respiratory Disease 22: 119-125. 2001

Riggle, P. C. and R. W. Harper, Bradycardia, p. 122-125. In: R. B. Taylor (Ed.) The Ten Minute Consult,. Lippencott, Williams, and Wilkins. 2000

Chang, M. M.-J., R. W. Harper, D. M. Hyde, and R. Wu. A novel mechanism of retinoic acid-enhanced interleukin-8 gene expression in airway epithelium. American Journal of Respiratory Cell and Molecular Biology 22: 502-510. 2000

Gianlupi, A., R. W. Harper, D. M. Dwyre and G. P. Marelich. Recurrent pulmonary embolism associated with Klippel-Trenaunay-Weber syndrome. Chest 115(4): 1199-1201. 1999