Clinical/Research Interests

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Select Recent Publications:

Ying L, Liu R, Zhang J, Lam KS, Lebrilla CB, Gervay-Hague J. A topologically segregated one-bead-one-compound combinatorial glycopeptide library for identification of high-affinity lectin ligands. Journal of Combinatorial Chemistry, 7:372-384.

Yao NH, Liu G, He WY, Niu C, Carlson JR, Lam KS. Solid-phase synthesis and antibacterial evaluations of N-demethylvancomycin derivatives. Bioorganic and Medicinal Chemistry Letters, 15:2325-2329.

Amano K, Leung PSC, Rieger R, Quan C, Wang X, Marik J, Suen YF, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M, Matsuura E, Coppel RL, Gershwin ME. Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: Identification of antibodies against a common environmental, cosmetic and food additive, 2-octynoic acid. Journal of Immunology, 174:5874-5883.

Aina O, Marik J, Liu R, Lau DH, Lam KS. Identification of novel targeting peptides for human ovarian cancer cells using OBOC combinatorial libraries. Molecular Cancer Therapeutics, 4:806-813.

Dixon S, Robins L, Elling RA, Liu R, Lam KS, Wilson DK, Kurth M. Discovery of selective aldose reductase ligands: An on-bead assay strategy. Bioorganic and Medicinal Chemistry Letters, 15:2938-2942.

Gillies RJ, Hoffman JM, Lam KS, Menkens AE, Piwnica-Worms DR, Sullivan J, Weissleder R. Meeting report: High-throughput technologies for in vivo imaging agents. Molecular Imaging, 4:1-6.

Wang X, Dixon S, Kurth M, Lam KS. Traceless solid-phase synthesis of 1,4-disubstituted-6-nitro-3,4-dihydro-1H-quinoline-2-ones. Tetrahedron Letter, 46:5361-5364.

Wang X, Dixon S, Kurth M, Lam KS. Microwave-assisted DIC-promoted intramolecular cyclization for solid-phase synthesis of trisubstituted imidazolidinones and pyrimidinones. Tetrahedron Letter, 46:5361-5364.

Dixon S, Wang X, Lam KS, Kurth M. Solid-phase synthesis of quinoxaline, thiazine and oxazine analogs through a benzyne intermediate. Tetrahedron Letter, 46:7443-7446.

Aina OH, Marik J, Gandour-Edwards R, Lam KS. Near-infrared optical imaging of ovarian cancer xenografts with novel a3-integrin-binding peptide “OA02.” Molecular Imaging, 4:439-447.