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UC Davis Health System

Robert H. Weiss, M.D.

Robert H. Weiss

Clinical/Research Interests

Robert H. Weiss' clinical interests include the diagnosis and treatment of all renal diseases and electrolyte problems. His research interests concern the cyclins and cyclin inhibitors, cancer growth control (kidney and breast cancer), metabolomics and proteomics, and polycystic kidney disease.

Title:

Professor
Chief of Nephrology, Sacramento VA Medical Center

Specialty:

Nephrology

Education:

UC Irvine College of Medicine
Irvine, California
M.D. 1984

UCLA
Los Angeles, California
M.S. 1980

UC Santa Cruz
Santa Cruz, California
B.A. 1976

Internships:

California-Pacific Medical Center
San Francisco, California
1984-85
Internal Medicine

Residency:

California-Pacific Medical Center
San Francisco, California
1985-87
Internal Medicine

Fellowships:

University of California, San Francisco
San Francisco, California
1991
Nephrology

Board Certifications:

American Board of Internal Medicine, Nephrology, 1996
American Board of Internal Medicine, 1987

Professional Memberships:

American Association for the Advancement of Science
American College of Physicians
American Society of Nephrology

Select Recent Publications:

Kim, K.M., Aronov, P.A., Zakharkin, S.O., Anderson, D., Perroud, B., Weiss, R.H., Urine metabolomic analysis for kidney cancer detection and biomarker discovery, Molecular and Cellular Proteomics, Mar;8(3):558-70, 2009

Perroud, B., Ishimaru, T., Borowsky, A.D., Weiss, R.H. Grade-dependent proteomic characterization of kidney cancer, Molecular and Cellular Proteomics, May;8(5):971-85, 2009

Liu , J.-Y. Park, S.-H., Morisseau , C., Hwang , S. H., Hammock, B., Weiss, R.H., Sorafenib Has sEH Inhibitory Activity Which Contributes to Its Effect Profile in vivo, Molecular Cancer Therapeutics, 2009 Aug;8(8):2193-203.

Son, A., Dhirapong, A., Dosev, D., Kennedy, I., Weiss, R.H., Hristova, K. Quantitative detection of PKD genetic mutations using magnetic/luminescent nanoparticles, Analytical and Bioanalytical Chemistry, 390(7):1829-35, 2008

Park, S.H., Park, J.Y., Weiss, R.H. Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA-damaging chemotherapy associated with enhancement of phospho-p53, Journal of Urology 180(1):352-60, 2008

Park, S.H., Wang, X., Liu, R., Lam, K.S., Weiss, R.H. High throughput screening of a small molecule one-bead-one-compound combinatorial library to identify attenuators of p21 as chemotherapy sensitizers, Cancer Biology & Therapy, Dec 26;7(12), 2015-22, 2008

Park, J.Y., Park, S.H., Weiss, R.H., Disparate effects of roscovitine on renal tubular epithelial cell apoptosis and senescence: Implications for ADPKD, American Journal of Nephrology, Dec 10;29(6):509-515, 2008

Weiss, R.H., Borowsky, A.D., Seligson, D. Lin, P.-Y., Dillard-Telm, L., Belldegrun, A. S., Figlin, R.A., Pantuck, A.D. p21 is a prognostic marker in renal cell carcinoma: Implications for novel therapeutic approaches, Journal of Urology, Jan;177(1):63-69, 2007

Kind, T., Tolstikov, V., Fiehn, O., Weiss, R.H. A comprehensive urinary metabolomic approach for identifying kidney cancer. Anal Biochem. 363(2):185-95, 2007

Lin, P.Y., Fosmire, S.P., Baksh, S., Modiano, J.F., Weiss, R.H. Attenuation of PTEN increases p21 stability and cytosolic localization: a potential mechanism of apoptosis resistance, Molecular Cancer, 6:16, 2007