Clinical/Research Interests

Basic Science which includes Autoimmunity, Lymphoma, Epstein-Barr virus infection in patients with inflammatory diseases, Mucosal immunity and HIV infection, Changes in colonic biota in patients with Inflammatory Bowel Disease, and Molecular profiling in patients with pancreatic neoplasia; and,

Clinical Science which includes Therapy of inflammatory bowel disease, Diagnosis and palliation of biliary and pancreatic neoplasia, Evaluation and treatment of strictures in patients with Inflammatory Bowel Disease, Effects of 6 MP methylation in the management of patients with IBD, Clinical outcomes in patients evaluated by capsule endoscopy, Effects of diet in patients with IBD.

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Select Recent Publications:

Sankaran S, George MD, Reay E, Guadalupe M, Flamm J, Prindiville T, Dandekar S. Rapid onset of intestinal epithelial barrier dysfunction in primary HIV infection is driven by imbalance between immune response and mucosal repair and regeneration. J Virol 2007

Foster EN MD, Quiros JA MD, Prindiville TP MD. Outcomes and long-term follow-up of the endoscopic treatment of strictures in pediatric and adult patients with inflammatory bowel disease (IBD). In Press American Journal of Clinical Gastroenterology

Ross WA, Wasan SM, Evans DB, Wolff RA, Trapani LV, Staerkel GA, Prindiville T, Lee JH. Combined Endoscopic Ultrasound with Fine-Needle Aspiration and Endoscopic Retrograde Cholangiopancreatography in the Evaluation of Patients Presenting with Obstructive Jaundice from Presumed Pancreatic Malignancy. In Press Gastrointestinal Endoscopy

Tu RH, Grewall P, Leung JW, Suryaprasad AG, Sheykhzadeh PI, Doan C, Garcia JC, Zhang N, Prindiville T, Mann S, Trudeau W. Diphenhydramine as an adjunct to sedation for colonoscopy : a double-blind randomized, placebo-controlled study. Gastrointestinal Endoscopy 63(1): 87-94.

Cohen SH, Shetab R, Tang-Feldman YJ, Sarma P, Silva J, Jr., Prindiville TP, Prevalence of enterotoxigenic Bacteroides fragilis in hospital-acquired diarrhea. Diagnostic Microbiology and Infectious Disease. 2006 ;55 :251-4

Guadalupe, M, Sankaran S, George MD, Reay E, Verhoeven D, Shacklett BL, Flamm J, Wegelin J, Prindiville T, Dandekar S. Viral Suppression and Immune Restoration in the Gastrointestinal Mucosa of Human Immunodeficiency Virus Type 1-Infected Patients Initiating Therapy during Primary or Chronic Infection. J Virol 2006;80:8236-47.

Park O, Grishina I, Leung PS, Gershwin ME, Prindiville T, Analysis of the Foxp3/scurfin gene in Crohn's disease. Ann New York Academy Science 2005 Jun; 1051:218-28.

Sankaran S, Guadalupe M, Reay E, George MD, Flamm J, Prindiville T, Dandekar S, Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors. Proceedings National Academy of Science U S A. 2005 Jul 12;102 (28):9860-5.

Shiekh R, Yasmeen S, Prindiville T, Ruebner B. Intestinal Perforation and Peritonitis in Aids: case series and review of the literature. International Journal of Current Medical Science and Practice 11(4): 248-256.