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Department of Radiation Oncology

Joerg Lehmann, Ph.D.

Joerg Lehmann

Clinical/Research Interests

While not involved directly in patient care, Dr. Lehmann has a strong interest in clinical research and implementation of new clinical technology. He works in the area of image-guided radiation therapy (IGRT), heading an image registry protocol. Dr. Lehmann works for the Advanced Technology Consortium (ATC), which facilitates the conduct of NCI-sponsored advanced technology radiation therapy clinical trials that require digital data submissions while maintaining patient confidentiality (atc.wustl.edu). He also is working on nanoparticle-enabled hyperthermia, specifically on combined nanoparticle thermotherapy and radiation therapy in cells and in a nude mouse model. One of Dr. Lehmann's strong interests is Monte Carlo simulations of radiation transport. He is working on electron beam modeling as a collaborator of a UCSF-based NIH grant. Using Monte Carlo simulations and measurements, Dr. Lehmann also is working on an industry-sponsored project investigating the impact of radiation treatment on mandibles containing metal plates. Dr. Lehmann has been involved in dosimetry for in vivo studies on the effect of low doses of ionizing radiation on humans for several years. This includes Monte Carlo simulations of radiation dose to areas outside the treatment fields and measurements in this low-dose region.

Title:

 Adjunct Assistant Professor

Center/Program Affiliation:

 UC Davis Cancer Center

Other Languages:

 German

Education:

 Technical University of Ilmenau
Ilmenau
Germany
Ph.D. 1999

Education:

 Technical University of Ilmenau
Ilmenau
Germany
B.S. 1991

Fellowships:

 Stanford University
Stanford, California
2000
Radiation Oncology

Board Certifications:

 American Board of Radiology, Therapeutic Radiological Physics, 2002
German Board Certification in Therapeutic Radiological Physics, 1998

Professional Memberships:

 American Association of Physicists in Medicine (AAPM)
Association of German Engineers (VDI)
European Society for Therapeutic Radiology and Oncology (ESTRO)
German Society for Medical Physics (DGMP)
Society of Nuclear Medicine (SNM)

Select Recent Publications:

Berglund SR, Schwietert CW, Jones A, Stern RL, Lehmann J, Goldberg Z. Optimized methodology for sequential extraction of RNA and protein from small human skin biopsies. Journal of Investigative Dermatology. (In press)

Lehmann J, DeNardo GL, Yuan A, Shen S, O'Donnell RT, Richman C, DeNardo SJ. Comparison of normal tissue pharmacokinetics with 111In/90Y monoclonal antibody m170 for breast and prostate cancer. Int J Radiat Oncol Biol Phys. (In press)

Lehmann J, Stern R, Daly T, Rocke D, Schwietert CW, Jones GE, Arnold ML, Hartmann Siantar C, Goldberg Z. Dosimetry for quantitative analysis of low-dose ionizing radiation effects on humans in radiation therapy patients. Rad Res, 165(2):240-247, 2006.

Goldberg Z, Rocke DM, Schwietert C, Berglund SR, Santana A, Lehmann J, Stern R, Hartmann Siantar C. Human in vivo dose response to low-dose low-LET ionizing radiation exposure. Clin Cancer Res, 12(12):3723-3729, 2006.

Wemple CA, Wessol DE, Nigg D, Cogliati J, Milvich M, Fredrickson CM, Perkins M, Harkin GJ, Hartmann Siantar C, Lehmann J, Flickinger T, Pletcher D, Yuan A, DeNardo G. MINERVA: A multi-modality plugin-based radiation therapy treatment planning system. Radiation Protection Dosimetry, 116(1-4):202-207, 2005.

Miller WH, Hartmann Siantar C, Fisher Darrell, Descalle M-A, Lehmann J, Volkert WA, Lewis MR, Hoffman T, Smith J, Situ P. Evaluation of absorbed fractions in a mouse model for 90Y, 188Re, 166Ho, 149Pm, 177Lu and 64Cu radioisotopes. Cancer Biother Radiopharm, 20(4):436-449, 2005.

Lehmann J, Hartmann Siantar C, Wessol DE, Wemple CA, Nigg D, Cogliati J, Daly TP, Descalle M-A, Flickinger T, Pletcher D, DeNardo G. Monte Carlo treatment planning for molecular-targeted radiotherapy within the MINERVA system. Phys Med Biol, 50:947-958, 2005.

Stern R, Kurylo J, Hartmann Siantar C, Lehmann J, Goldberg Z. Film dosimetry in the peripheral region using multiple sensitometric curves. Med Phys, 31(2):327-332, 2004.

Lehmann J, Stern R, Levy J, Daly T, Hartmann Siantar C, Goldberg Z. Radiation phantom with humanoid shape and adjustable thickness (RPHAT). Phys Med Biol, 49(9):N125-N129, 2004.

King CR, Lehmann J, Adler JR, Hai J. CyberKnife radiotherapy for localized prostate cancer: Rationale and technical feasibility. Technol Cancer Res Treat, 2(1):25-30, 2003.