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Department of Radiation Oncology

Department of Radiation Oncology

Novel Calypso study for advanced cervical cancer

November 15, 2011

Jyoti Mayadev © UC Regents
Dr. Jyoti Mayadev

Calypso technology uses implantable electromagnetic markers to track tumor motion during radiation therapy.  Used mostly in the treatment of prostate cancer, we are excited to have a novel research study to investigate the movement of the cervix in patients with locally advanced cervical cancer.  Dr. Jyoti Mayadev, a specialist in gynecologic malignancies, in conjunction with colleagues at UC Davis Medical Center and Emory University Hospital, are planing to enroll 10 patients with intact cervical cancer who will receive radiation therapy for curable intent.  Calypso transponders will be implanted into the cervix and will be able to give the physician and research team a real time picture of the cervix during treatment with radiation.  Using this information, the treatment team will better understand cervical motion both during treatment, and between radiation daily treatments.  This fascinating study will eventually provide data to decrease the dose to important organs close to the radiation field in cervical cancer, such as the bladder and rectum, and increase the dose to the cervical tumor.