Philosophy of Care
Dr. Sageshima believes that "transplantation" requires teamwork among multidisciplinary team members, and a patient and family members are the most important part of the transplant team.
As a transplant surgeon, he aims to provide more opportunities and better outcomes to patients with end-stage organ disease by optimizing organ recovery, preservation, transplant surgery and pre-/post-surgery management.
Dr. Sageshima is a transplant surgeon offering care for patients with end-stage organ disease. He has special clinical interest and expertise in adult and pediatric kidney and pancreas transplantation, organ recovery and preservation, live donor surgery, and vascular and peritoneal access surgery.
Dr. Sageshima’s research focuses on improving the transplant outcomes, especially through new methods of organ recovery, preservation, and transplantation. He also has interest in clinical and translational transplant research.
M.D., Showa University School of Medicine, Shinagawa, Tokyo, Japan 1990
Surgery, Tokyo Women's Medical College Hospital, Tokyo, Japan 1996
Transplant Surgery, University of Miami/Jackson Memorial Hospital, Miami FL 2004
American Society of Transplant Surgeons - Transplant Surgery, 2004
CA Physicians and Surgeon, 2016
Japan Surgical Society, 2013
American College of Surgeons
American Society of Transplant Surgeons
International Pancreas and Islet Transplant Association
The International Society for Organ Donation and Procurement
The Japan Surgical Society
The Transplantation Society
Select Recent Publications
Paloyo S, Sageshima J, Gaynor JJ, Chen L, Ciancio G, Burke GW. Negative impact of prolonged cold storage time before machine perfusion preservation in donation after circulatory death kidney transplantation. Transpl Int. Oct 2016;29(10):1117-1125.
Sageshima J, Ciancio G, Chen L, Dohi T, El-Hinnawi A, Paloyo S, Misawa R, Ekwenna O, Yatawatta A, Burke GW, 3rd. Everolimus with low-dose tacrolimus in simultaneous pancreas and kidney transplantation. Clin Transplant. Jul 2014;28(7):797-801.
Yu CC, Fornoni A, Weins A, Hakroush S, Maiguel D, Sageshima J, Chen L, Ciancio G, Faridi MH, Behr D, Campbell KN, Chang JM, Chen HC, Oh J, Faul C, Arnaout MA, Fiorina P, Gupta V, Greka A, Burke GW, 3rd, Mundel P. Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med. 2013; 369(25):2416.
Ciancio G, Sageshima J, Akpinar E, Gaynor JJ, Chen L, Zarak A, Hanson L, Tueros L, Guerra G, Mattiazzi A, Kupin W, Roth D, Ricordi C, Burke GW, 3rd. A randomized pilot study of donor stem cell infusion in living-related kidney transplant recipients receiving alemtuzumab. Transplantation. 2013; 96(9):800.
Ciancio G, Sageshima J, Chen L, Gaynor JJ, Hanson L, Tueros L, Velarde EM, Gomez C, Kupin W, Guerra G, Mattiazzi A, Fornoni A, Pugliese A, Roth D, Wolf M, Burke Iii GW. Advantage of rapamycin over mycophenolate mofetil when used with tacrolimus for simultaneous pancreas kidney transplants: randomized, single-center trial at 10 years. Am J Transplant. 2012; 12(12):3363.
Hibi T, Sageshima J, Molina E, Ciancio G, Nishida S, Chen L, Arosemena L, Mattiazzi A, Guerra G, Kupin W, Tekin A, Selvaggi G, Levi D, Ruiz P, Livingstone AS, Roth D, Martin P, Tzakis A, Burke GW. Predisposing Factors of Diminished Survival in Simultaneous Liver/Kidney Transplantation. Am J Transplant. 2012; 12(11):2966.
Ciancio G, Gaynor JJ, Sageshima J, Roth D, Kupin W, Guerra G, Tueros L, Zarak A, Hanson L, Ganz S, Chen L, Ruiz P, Livingstone AS, Burke GW, 3rd. Machine perfusion following static cold storage preservation in kidney transplantation: donor-matched pair analysis of the prognostic impact of longer pump time. Transpl Int. 2012; 25(1):34.
Wei C, El Hindi S, Li J, Fornoni A, Goes N, Sageshima J, Maiguel D, Karumanchi SA, Yap HK, Saleem M, Zhang Q, Nikolic B, Chaudhuri A, Daftarian P, Salido E, Torres A, Salifu M, Sarwal MM, Schaefer F, Morath C, Schwenger V, Zeier M, Gupta V, Roth D, Rastaldi MP, Burke G, Ruiz P, Reiser J. Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med. 2011; 17(8):952.
Sageshima J, Ciancio G, Guerra G, Gaynor JJ, Cova D, Zarak A, Chen L, Mattiazzi A, Kupin W, Roth D, Hanson L, Livingstone AS, Ruiz P, Burke GW. Prolonged lymphocyte depletion by single-dose rabbit anti-thymocyte globulin and alemtuzumab in kidney transplantation. Transpl Immunol. 2011; 25(2-3):104.
Fornoni A, Sageshima J, Wei C, Merscher-Gomez S, Aguillon-Prada R, Jauregui AN, Li J, Mattiazzi A, Ciancio G, Chen L, Zilleruelo G, Abitbol C, Chandar J, Seeherunvong W, Ricordi C, Ikehata M, Rastaldi MP, Reiser J, Burke GW, 3rd. Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis. Sci Transl Med. 2011; 3(85):85ra46.