Richart William Harper, M.D.
Professor of Medicine
Interim Division Chief, Pulmonary, Critical Care and Sleep Medicine
To see if Richart William Harper is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).
Locations and Contact
UC Davis Medical Group - Sacramento (J Street)
Pulmonary, Critical Care and Sleep Medicine
2825 J St.
Sacramento, CA 95816
Phone: 916-734-8230
Fax: 916-734-4582
Clinical Interests
Dr. Harper specializes in the diagnosis and management of patients with critical illness and diffuse parenchymal lung diseases. He predominantly sees patients with sarcoidosis. He also provides expertise in cardiopulmonary exercise testing to diagnose patients with unexplained shortness of breath, or to better assess response to therapy.
Research/Academic Interests
Dr. Harper's research includes the study of mucosal innate immunity and allergic responses. This includes the study of mechanisms that are critical for neutrophil recruitment in the airway epithelium.
Division
Pulmonary, Critical Care, and Sleep Medicine
Center/Program Affiliation
Undergraduate School
B.S., Physics, UC San Diego, San Diego CA 1988
Medical School
M.D., Georgetown University School of Medicine, Washington, D.C., 1993
Residency
Internal Medicine, UC Davis Medical Center, Sacramento CA 1993-1996
Fellowship
Pulmonary and Critical Care Medicine, UC Davis Medical Center, Sacramento CA 1996-1999
Excellence in Teaching Award, Pulmonary Fellowship Program, 2018, 2019
Best Attending by Fellowship Program Choice, Pulmonary and Critical Care Fellowship Program, 2013
Excellence in Teaching Award, Pulmonary Fellowship Program, 2012, 2013
To view Dr. Harper's publications, please click here.
Cagle L, Linderholm A, Franzi L, Hoehne S, Last J, Kenyon N, Illek B, Harper R. Role of Dual Oxidases in Ventilator-induced Lung Injury. Am J Respir Cell Mol Biol. 2021 Feb;64(2):208-215. doi:10.1165/rcmb.2020-0197OC. PMID:33253594.
McCartney MM, Yamaguchi MS, Bowles PA, Gratch YS, Iyer RK, Linderholm AL, Ebeler SE, Kenyon NJ, Schivo M, Harper RW, Goodwin P, Davis CE. Volatile organic compound (VOC) emissions of CHO and T cells correlate to their expansion in bioreactors. J Breath Res. 2019 Oct 21;14(1):016002. doi:10.1088/1752-7163/ab3d23. PMID:31430743.
Yamaguchi MS, McCartney MM, Falcon AK, Linderholm AL, Ebeler SE, Kenyon NJ, Harper RH, Schivo M, Davis CE. Modeling cellular metabolomic effects of oxidative stress impacts from hydrogen peroxide and cigarette smoke on human lung epithelial cells. J Breath Res. 2019 Jun 19;13(3):036014. doi:10.1088/1752-7163/ab1fc4. PMID:31063985.
Liao SY, Linderholm AL, Yoneda KY, Kenyon NJ, Harper RW. Airway transcriptomic profiling after bronchial thermoplasty. ERJ Open Res. 2019 Feb 18;5(1):00123-2018. doi:10.1183/23120541.00123-2018. PMID:30792984.
Cagle LA, Franzi LM, Linderholm AL, Last JA, Adams JY, Harper RW, Kenyon NJ. Effects of positive end-expiratory pressure and recruitment maneuvers in a ventilator-induced injury mouse model. PLoS One. 2017 Nov 7;12(11):e0187419. doi:10.1371/journal.pone.0187419. PMID:29112971.
Black C, Gerriets JE, Fontaine JH, Harper RW, Kenyon NJ, Tablin F, Schelegle ES, Miller LA. Early Life Wildfire Smoke Exposure Is Associated with Immune Dysregulation and Lung Function Decrements in Adolescence. Am J Respir Cell Mol Biol. 2017 May;56(5):657-666. doi:10.1165/rcmb.2016-0380OC. PMID:28208028.
Chang S, Linderholm A, Harper R. DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways. PLoS One. 2015 Jul 6;10(7):e0131810. doi:10.1371/journal.pone.0131810. PMID:26148206.
Chang S, Linderholm A, Franzi L, Kenyon N, Grasberger H, Harper R. Dual oxidase regulates neutrophil recruitment in allergic airways. Free Radic Biol Med. 2013 Dec;65:38-46. doi:10.1016/j.freeradbiomed.2013.06.012. Epub 2013 Jun 11. PMID:23770197.
Xu C, Linderholm A, Grasberger H, Harper RW. Dual oxidase 2 bidirectional promoter polymorphisms confer differential immune responses in airway epithelia. Am J Respir Cell Mol Biol. 2012 Oct;47(4):484-90. doi:10.1165/rcmb.2012-0037OC. Epub 2012 May 16. PMID:22592922.