Xiaosong Jiang, M.D., Ph.D.

Xiaosong Joy Jiang, M.D., Ph.D.

Specialties

Research on Liver Disease

Title

  • Associate Adjunct Professor, Gastroenterology and Hepatology

Education

M.D., Capital Medical University, Beijing China 1998

M.S., Neurobiology, Hong Kong University of Science and Techolology, Hong Kong China 2003

Ph.D., Nutritional Biology, UC Davis, Davis CA 2012

Residency

Internal Medicine, Peking University - Shougang Hospital, Beijing China 1998

Honors and Awards

Richard C. Woodard Research Award, Internal Medicine , UC Davis, 2013

Select Recent Publications

Bettaieb, A.*, Jiang, J.X.*, Sasaki, Y., Chao, T.I., Kiss, Z., Chen, X., Tian, J., Katsuyama, M., Yabe-Nishimura, C., Xi, Y., Szyndralewiez, C., Schröder, K., Shah, A., Brandes, R.P., Haj, F.G. and Török, N.J. Hepatocyte NADPH oxidase 4 regulates stress signaling, fibrosis, and insulin sensitivity during development of steatohepatitis in mice. Gastro. pii: S0016-5085(15)00509-0. doi: 10.1053/j.gastro. 2015.04.009. (IF:13.926) (*equal contribution)

Jiang, J.X. And Török, N.J. MLK3 as a regulator of disease progression in NASH. Liver Int. 2014 DOI: 10.1111/liv. 12556.

Jiang, J.X. and Török, N.J. Liver injury and the activation of hepatic myofibroblasts. Curr. Pathobiol. Rep. 2013; 1(3): 215-223.

Jiang, J.X., Chen, X., Fukada, H., Serizawa, N., Devaraj, S., and Török, N.J. Advanced glycation end products induce inflammatory and fibrogenic activity in NASH by modulating the TNFα converting enzyme activity. Hepatol. 2013; 58(4):1339-1348.

Medici, V., Shibata, N., Kharbanda, K.K., LaSalle, J.M., Woods, R., Liu, S., Engelberg, J., Cardiff, R.D., Havel, P.J., Devaraj, S., Török, N.J., Jiang, J.X., Lönnerdal, B., Kim, K., Halsted, C.H. Wilson disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease. Hepatol. 2012;57(2):555-565.

Jung, C.J., Iyengar, S., Blahnik, K.R., Jiang, J.X., Tahimic, C., Török, N.J., de Vere White, R.W., Farnham, P.J., Zern, M. Human ESC Self-renewal Promoting microRNAs Induce Epithelial–Mesenchymal Transition in Hepatocytes by Controlling the PTEN and TGFβ Tumor Suppressor Signaling Pathways. Mol Cancer Res. 2012; 10(7):979-991.

Jiang, J.X., Chen, X., Serizawa, N., Szyndralewiez, C., Page, P., Schröder, K., Brandes, R.P., Devaraj, S., Török, N.J. Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo. Free Radic Biol Med. 2012;53(2):289-296.

Jiang, J.X., Chen, X., Hsu, D., Baghy, K., Serizawa, N., Scott, F., Takada, Y., Takada, Y., Fukada, H., Chen, J., Devaraj, S., Adamson, R., Liu, F.T. and Török, N.J. Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo. Am. J. Physiol. Gastrointest. Liver Physio. 2012;302(4): G439-446.

Jung, C.J., Iyengar, S., Blahnik, K.R., Ajuha, T.P., Jiang, J.X., Farnham, P.J., Zern, M. Epigenetic modulation of miR-122 facilitates human embryonic stem cell selfrenewal and hepatocellular carcinoma proliferation. PLoS One 2011;6(11):e27740.

Medici, V., Ali, M., Seo, S., Aoki, C., Rossaro, L., Kim, K., Fuller, W., Vidovszky, T., Smith, W., Jiang, J.X., Maganti, K., Havel, P.J., Kamboj, A., Ramsamooj, R. and Török, N.J. Increased Soluble leptin receptor levels in morbidly obese patients with insulin resistance and nonalcoholic fatty liver disease. Obesity. 2010;18(12):2268-2273.