The molecular genetics and functional genomics of neuropsychiatric and neurodegenerative disorders.
Ph.D., Indian Institute of Science, Bangalore, 1976
M.Sc., University of Bombay, Bombay, India, 1969
B.Sc., Andhra University, Waltair, 1966
American Association for the Advancement of Sciences, Washington, D.C., 1986
Rockefeller Foundation, New York, New York, 1990
Royal Society of Chemistry, London, 2000
Royal Society of Tropical Medicine & Hygiene, London, 1999
Washington Academy of Sciences, Washington, D.C., 1985
Human Proteome Organization
International Brain Research Organization
Society for Neuroscience
Honors and Awards
Royal Society of Chemistry Elected Fellow, 2000
Rolex International Award for Enterprise Associate Laureate, 1993
Rockefeller Foundation Biotechnology Career Fellow, 1990
Jawaharlal Nehru Centenary Lectureship, 1989
American Association for the Advancement of Sciences Elected Fellow, 1986
Select Recent Publications
Choudary PV. Power troubles in Parkinson's disease. Commentary. CNS Neurol Disord Drug Targets. 2011 Mar;10(2):146.
Choudary PV, J Knowles. Genetics. In: American Psychiatric Publishing Text Book of Psychiatry (Eds. Robert E Hales, Stuart C. Yudofsky, and Glen O. Gabbard), 199-251, 2008.
Murray KD, PV Choudary, EG Jones. Nuc1eus- and cell-specific gene expression in monkey thalamus. Proc NatI Acad Sci USA 104:1989-1994, 2007, PMID: 17261798.
Vawter MP, H Tomita, F Meng, B Bolstad, JZ Li, SJ Evans, PV Choudary, ME Atz, L Shao, CR Neal, DM Walsh, TP Speed, RM Myers, EG Jones, SJ Watson, H Akil, WE Bunney Jr. Mitochondrial related genes are sensitive to agonal-pH state: implications for brain disorders. Mol Psychiatry 11:615; 663-679, 2006, PMID: 16636682.
Karssen AM, JZ Li, S Her, PD Patel, F Meng, SJ Evans, MP Vawter, H Tomita, PV Choudary, WE Bunney Jr, EG Jones, SJ Watson, H Akil, RM Myers, AF Schatzberg, DM Lyons. Application of micro array technology in primate behavioral neuroscience research. Methods 38:227-234, 2006, PMID: 16469505.
Choudary PV, M Molnar, SJ Evans, H Tomita, JZ Li, MP Vawter, RM Myers, WE Bunney Jr, H Akil, SJ Watson, EG Jones. Altered cortical glutamatergic and GABAergic signal transmission and glial involvement in major depression. Proc Natl Acad Sci USA 102:15653-15658, 2005, PMID: 16230605.
Li JZ, MP Vawter, DM Walsh, H Tomita, SJ Evans, PV Choudary, JF Lopez, A Avelar, V Shokoohi, T Chung, 0 Mesarwi, EG Jones, SJ Watson, H Akil, WE Bunney Jr, RM Myers. Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. Human Mol Genetics 13:609-616, 2004, PMID: 14734628. [see "news and views in brief," Nature 427: 501, 2004]
Evans SJ, PV Choudary, CR Neal, JZ Li, MP Vawter, H Tomita, JF Lopez, RC Thompson, F Meng, JD Stead, DM Walsh, RM Myers, WE Bunney Jr, SJ Watson, EG Jones, H Akil. Dysregulation of the fibroblast growth factor system in major depression. Proc Natl Acad Sci USA 101:15506-15511, 2004, PMID: 15483108. [see "research highlights," Nature 431: 1051, 2004]
Tomita H, MP Vawter, DM Walsh, SJ Evans, PV Choudary, JZ Li, KM Overman, ME Atz, RM Myers, EG Jones, SJ Watson, H Akil, WE Bunney Jr. Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain. Bioi Psychiatry 55: 346-352, 2004, PMID: 14960286.
WE Bunney Jr, BG Bunney, MP Vawter, H Tomita, J Li, SJ Evans, PV Choudary, RM Myers, EG Jones, SJ Watson, H Akil. Microarray technology: a review of new strategies to discover candidate vulnerability genes in psychiatric disorders. Am J Psychiatry 160: 657-666,251, 2003, PMID: 1266835l.
Evans SJ, PV Choudary, MP Vawter, J Li, JH Meador-Woodruff, SM Burke, RC Thompson, RM Myers, EG Jones, WE Bunney, SJ Watson, H Akil. DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles. Neurobiol Disease 14: 240-250, 2003, PMID: 14572446.