Lee-Way Jin, M.D., Ph.D.
Molecular, Cellular, and Integrative Physiology
- Director of Neuropathology
D.r Jin's clinical interests are in neuropathology.
Dr. Jin's research interests include Autism spectrum disorders and Alzheimer's disease.
M.D., Neuropathology, National Taiwan University, Taipei City, Taiwan, 1985
Ph.D., Molecular Pathology and Neuroscience, UC San Diego, San Diego CA 1993
Anatomic Pathology, UC San Diego Medical Center, San Diego CA
Neuropathology, University of Washington, Seattle WA
Society for Neuroscience
Select Recent Publications
Brich J, Shie F-S, Howell BW, Li R, Tus K, Wakeland EK, Jin L-W, Mumby M, Churchill G, Herz J, Cooper JA. Genetic modulationof tau phosphorylation in the mouse. J Neurosci. 2003;23:187-192.
Cook DG, Leverenz JB, Ericksen S, Roth RA, Schellenberg GD, Jin L-W, Kovacina KS, Craft S. Reduced hippocampal insulin degrading enzyme in late onset Alzheimerˇs disease is associated with the apolipoprotein E-epsilon4 allele. Am J Pathol. 2003;162:313-319
Kurimoto M, MÃ¼ller B, Kaminsky W, Kahr B, Jin L-W. Dyeing Crystals to Dyeing Tissues: Congo Red in Anisotropic Media. Molecular Crystals and Liquid Crystals. 2002;389:1-9.
Bu B, Klunemann H, Suzuki K, Li J, Bird T, Jin L-W, Vincent I. Niemann-Pick disease type C yields possible clue for why cerebellar neurons do not form neurofibrillary tangles. Neurobiol Dis. 2002;11:285-297.
Jin L-W, Hua DH, Shie F-S, Maezawa I, Sopher B, Martin GM. Novel tricyclic pyrone compounds prevent intracellular APP C99-induced cell death. J Mol Neurosci. 2002;19:57-61.
Xu J, Kao S-Y, Lee FJ, Song W, Jin L-W, Yankner BA. Dopamine-dependent neurotoxicity of native alpha-synuclein: a mechanism for selective neurodegeneration in Parkinsonˇs disease. Nature Medicine. 2002;8:600-606.
Shie FS, Jin L-W, Leverenz JB, LeBoeuf RC. Diet-induced hypercholesterolemia enhances accumulation of Abeta in a mouse model of Alzheimerˇs disease. NeuroReport. 2002;13:455-459.
Vuletic S, Jin L-W, Marcovina SM, Peskind ER, MÃ¼ller T, Albers JJ. Widespread distribution of plasma phospholipids transfer protein in human central nervous system: evidence for PLTP synthesis by glia and neurons and for altered PLTP distribution in Alzheimerˇs disease. J Lipid Res. 2003;44:1113-1123.
Shie FS, LeBoeuf RC, Jin L-W. Early intraneuronal Abeta deposition in the CA1 of APP transgenic mice. NeuroReport. 2003;14:123-129.
Maezawa I, Wang B, Hu Q, Martin GM, Jin L-W, Oshima J. Alterations of chaperone protein expression in presenilin mutant neurons in response to glutamate excitotoxicity. Pathol Int. 2002;52:551-554.