Philosophy of Care
In working with patients, I use a careful and efficient application of scientific knowledge to the artful practice of pulmonary medicine. I strongly believe that UC Davis makes a special contribution to the Sacramento-area community through the heartfelt concern of medical students, house staff and faculty for the health and welfare of the patients it serves.
Dr. Cross serves as co-director of UC Davis' Adult Cystic Fibrosis Clinic and also has a special interest in alpha-antitrypsin deficiency (congenital emphysema). He has produced over 200 publications on topics related to inhalation toxicology, with a focus on oxidants including ozone, oxides of nitrogen and cigarrette smoke, and antioxidant micronutrients. He also has published on several aspects of clinical lung disease.
Pulmonary and Critical Care Medicine
M.D., Columbia University, College of Physicians and Surgeons, New York, New York, 1961
B.A., Pomona College, Claremont, California, 1957
Stanford University, School of Medicine, Palo Alto, California, 1962-1964
University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, 1964-68
American Board of Internal Medicine, 1969
American Board of Internal Medicine, Pulmonary Disease, 1971
American Federation for Clinical Research
American Physiological Society
American Thoracic Society
British Thoracic Society
The Society of Free Radicals in Biology and Medicine
Western Society of Physicians
Honors and Awards
California Medal, 2000
Fulbright Fellowship, 1982
Select Recent Publications
Morrissey, B.M., B.C. Schock, G.P. Marelich and C.E. Cross. Cystic fibrosis in adults: current and future management strategies. Clin Rev in Allergy & Immunol 25:275-288, 2004.
Reznick, A.Z., Klein, J.P. Eiserich, C.E. Cross and R.M. Nagler. Inhibition of oral peroxidase activity by cigarette smoke: in vivo and in vitro studies. Free Radical Biology & Medicine 34:377-384, 2003.
Valacchi, G., E. Pagnin, R. Okamoto, A.M. Corbacho, E. Olano, O.A. Davis, A. van der Vliet, L. Packer and C.E. Cross. Induction of stress proteins and MMP-9 by 0.8 ppm of ozone in murine skin. Biochemical and Biophysical Research Communications 305:1-6, 2003.
Dietrich, M., G. Block, E.P. Norkus, M. Hudes, M.G. Traber, C.E. Cross and L. Packer. Smoking and exposure to environmental tobacco smoke decrease some plasma antioxidants and increase ?-tocopherol in vivo after adjustment for dietary antioxidant intakes. American Journal of Clinical Nutrition 77:160-166, 2003.
Cross, C.E.. The antioxidant milieu at asthmatic respiratory tract surfaces. Pediatric Research 53:365-368, 2003.
Morrissey, B.M., A. van der Vliet, J. Eiserich and C.E. Cross. Chapter 12, p. 261-283. Oxidative and nitrosative stress in cystic fibrosis: significance or triviality. In: J. Fuchs, M. Podda and L. Packer (Eds.) Redox-Genome Interaction in Health and Disease. Marcel Dekker, Inc., New York, 2003.
Corbacho, A.M., Y. Macotela, G. Nava, J.P. Eiserich, C.E. Cross, G.M. de la Escalera and C. Clapp. Cytokine induction of prolactin receptors mediates prolactin inhibition of nitric oxide synthesis in pulmonary fibroblasts. FEBS 544:171-175, 2003.
Cross, C.E., G. Valacchi, B. Schock, M. Wilson, S. Weber, J. Eiserich and A. van der Vliet. Environmental oxidant pollutant effects on biologic systems: a focus on micronutrient antioxidant-oxidant interactions. American Journal of Respiratory and Critical Care Medicine 166:S44-S50, 2002.
Dietrich, M, G Block, M Hudes, JD Morrow, EP Norkus, MG Traber, CE Cross and L Packer. Antioxidant supplementation decreases lipid peroxidation biomarker F2-isoprostanes in plasma of smokers. Cancer Epidemiology, Biomarkers Prevention 2002:11:7-13, 2002.
Cross, CE, G Valacchi, BC Schock, M Wilson, S Weber, JP Eiserich, and A. van der Vliet. Environmental oxidant pollunts effects on biologic systems. A focus on micronutrient antioxidant-oxidant interactions. amer J Resp Crit Care Med 166, 2002.