Barbara Weiser, M.D.
- Professor in Residence, Department of Medicine
VA Northern CA Health Care System
10535 Hospital Way
Mather, CA 95655
Additional Phone Numbers
Philosophy of Care
My philosophy of care is based on communication with patients. I listen to and focus on the patient.
Dr. Weiser's research interests include: HIV research, in particular research on HIV tropism, pathogenesis and disease progression in infected individuals.
Dr. Weiser is an inventor of six patented technologies issued between 2004 and 2011 for the analysis of HIV 1 tropism in the clinical care of HIV-1-infected patients. Licensed to Quest Diagnostics, Inc, these technologies serve as the basis for Quest’s clinical test, "HIV-1 Coreceptor Tropism Assay." The patents and licenses are owned by Health Research Inc.
M.D., University of Pittsburgh School of Medicine, Pittsburgh PA 1975
A.B., Vassar College, Poughkeepsie NY 1969
Bellevue Hospital New York University Medical Center, New York NY 1976-1978
Infectious Diseases, Memorial Sloan-Kettering Cancer Center, New York NY 1978-1980
Molecular Virology, Stanford University School of Medicine, Stanford CA 1984-1985
Molecular Virology, UC San Francisco, San Francisco CA 1980-1983
American Board of Internal Medicine, 1978
American Society of Microbiology
Infectious Disease Society of America
International AIDS Society
Honors and Awards
American Cancer Society Postdoctoral Research Fellowship, 1981
NIH Clinical Investigator Award, 1982
Mary Pangborn Award for Research with an Impact on Clinical Medicine, New York State Dept of Health, 1997
Select Recent Publications
Weber S, Weiser B, Kemal KS, Burger H, Ramirez, CR, Korn K, Anastos K, Kaul R, Kovacs C, Doerfler W. Epigenetic analysis of HIV-1 proviral genomes from infected individuals: predominance of unmethylated CpG’s. Virology, 2014;449:181-189.
Kemal KS, Kitchen C, Burger H, Klimkait T, Hamy F, Foley B, Mayers D, Anastos K, Petrovic K, Suchard M, Minin V, Weiser B. Recombination between variants from genital tract and plasma: evolution of multidrug resistant HIV-1. AIDS Res and Hum Retroviruses; 2012;28:1766-74.
Shi B, Kitchen C, Weiser B, Mayers D , Foley B, Kemal K, Anastos K, Suchard M, Parker M, Brunner C, Burger H. Evolution and recombination of genes encoding HIV-1 drug resistance and coreceptor usage during antiretroviral therapy, Virology, 2010;404:5-20.
Weiser B, Philpott S, Klimkait T, Burger H, Kitchen C, Bürgisser P, Gorgievski M, Perrin L, Piffaretti J-C, Ledergerber B, and the Swiss HIV Cohort Study. HIV-1 coreceptor usage and CXCR4-specific viral load predict clinical disease progression during combination antiretroviral therapy. AIDS; 2008;22:469-479.
Kemal KS, Burger H, Mayers D, Anastos K, Foley B, Kitchen C, Huggins P, Schroeder T, Picchio G, Back S, Gao W, Meyer WA III, Weiser B. HIV-1 drug resistance in variants from the female genital tract and plasma. J Infect Dis. 2007;195:535-545.
Kemal KS, Foley B, Burger H, Anastos K, Minkoff H, Kitchen C, Philpott S, Gao W, Robison E, Holman S, Dehner C, Beck S, Meyer W, Landay A, Kovacs A, Bremer J, Weiser B. HIV-1 in genital tract and plasma of women: compartmentalization of viral sequences, coreceptor usage, and glycosylation. Proc Natl Acad Sci USA. 2003;100:12972-12977.
Philpott S, Weiser B, Anastos K, Kitchen CMR, Robison E, Meyer WA, Sacks HS, Mathur-Wagh U, Brunner C, and Burger H. Preferential suppression of CXCR4-specific strains of HIV-1 by antiviral therapy. J Clin Invest. 2001;107:431-438.
Fang G, Burger H, Grimson R, Tropper P, Nachman S, Mayers D, Weislow O, Moore R, Reyelt C, Hutcheon N, Baker D, and Weiser B. Maternal plasma human immunodeficiency virus type 1 RNA level: a determinant and projected threshold for mother-to-child transmission. Proc Natl Acad Sci USA. 1995;92:12100-12104.
Weiser B, Nachman S, Tropper P, Viscosi KH, Grimson R, Baxter G, Fang G, Reyelt C, Hutcheon N, and Burger H. Quantitation of human immunodeficiency virus type 1 during pregnancy: relationship of viral titer to mother-to-child transmission and stability of viral load. Proc Natl Acad Sci USA. 1994;91:8037-8041.
Burger H, Weiser B, Flaherty K, Gulla J, Nguyen P, and Gibbs RA. Evolution of human immunodeficiency virus type 1 nucleotide sequence diversity among close contacts. Proc Natl Acad Sci USA. 1991;88:11236-11240.