Harold Burger, M.D., Ph.D.

Harold Burger, M.D., Ph.D.

Specialties

Infectious Diseases

Internal Medicine

Title

  • Professor of Medicine in Residence
To see if Harold Burger is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

VA Northern CA Health Care System

10535 Hospital Way
Mather, CA 95655
Driving Directions

Primary Phone:
916-843-7000

Additional Phone Numbers

Phone: 916-734-3815
Clinic Phone: 916-843-9285

Emails

Center/Program:
hburger@ucdavis.edu

Philosophy of Care

Respect for patients

Research/Academic Interests

Dr Burger's research interests include: HIV research, in particular  HIV tropism and other determinants of HIV pathogenesis and disease progression.

Technology Transfer

Six Patents on: 

"Analysis of HIV-1 Coreceptor Use in the Clinical Care of HIV-1 Infected Patients," and "Heteroduplex Tracking Assay," US Patents  2004, 2007, 2008, 2010, 2011 

The patented technologies are licensed to Quest Diagnostics and serve as the basis for its clinical test, "HIV-1 Coreceptor Tropism Assay." 

Patents and licenses are owned by Health Research Inc.

Division

Infectious Diseases

Education

M.D., Albert Einstein College of Medicine, Bronx NY 1978

Ph.D., Virology, The Rockefeller University, New York NY 1976

B.S., University of Chicago, Chicago IL 1969

Residency

Montefiore Hospital Medical Center, Bronx NY 1979-1980

Stanford University Hospital, Stanford CA 1980-1981

Fellowships

Infectious Disease, Stanford University Medical Center, Stanford CA 1981-1985

Board Certifications

American Board of Internal Medicine, 1981

Medical Board of California, 2015

Professional Memberships

American Society for Microbiology

Honors and Awards

Leo Davidoff, M.D., Teaching Award, Montefiore Hospital, New York, 1980

Clinical Investigator Award, National Heart Lung and Blood Institute, 1982

Mary Pangborn Award for Research, New York State Department of Health, 1997

Select Recent Publications

Weber S,  Weiser B, Burger H, Ramirez  C,  Kemal  K, Korn K, Anastos K, Kaul R, Kovacs C, Doerfler W. Epigenetic analysis of HIV-1 proviral genomes from infected individuals: predominance of unmethylated CpGs. Virology. 2014;449: 181-189.

Shi B, Kitchen C,  Weiser B, Mayers D , Foley B, Kemal K, Anastos K, Suchard M, Parker M, Brunner C, Burger H. Evolution and recombination of genes encoding HIV-1 drug resistance and coreceptor usage during antiretroviral therapy. Virology. 2010;404:5-20.

Weiser B, Philpott S, Klimkait T, Burger H, Kitchen C, Burgisser P, Gorgievski M, Perrin L, Piffaretti J-C, Ledergerber B, and the Swiss HIV Cohort Study. HIV-1 coreceptor usage and CXCR4-specific viral load predict clinical disease progression during combination antiretroviral therapy. AIDS. 2008;22:469-79. 

Fang G, Weiser B, Kuiken C, Philpott S, Rowland-Jones S, Plummer F, Kimani J, Shi B, Kaul R, Bwayo J, Anzala O, and Burger H. Recombination following superinfection by HIV-1. AIDS. 2004;18:153-159.

Kemal KS, Foley B, Burger H, Anastos K, Minkoff H, Kitchen C, Philpott S, Gao W, Robison E, Holman S, Dehner C, Beck S, Meyer W, Landay A, Kovacs A, Bremer J, Weiser B. HIV-1 in genital tract and plasma of women: compartmentalization of viral sequences, coreceptor usage, and glycosylation. Proc Natl Acad Sci USA. 2003;100:12972-12977.

Philpott S, Weiser B, Anastos K, Ramirez-Kitchen CM, Robison E, Meyer WA, Sacks HS, Mathur-Wagh U, Brunner C, and Burger H. Preferential suppression of CXCR4-specific strains of HIV-1 by antiviral therapy. J Clin Invest. 2001;107:431-438.

Fang, G, Weiser, B, Visosky A, Moran, T, Burger, H. PCR-mediated recombination: a general method applied to construct chimeric infectious molecular clones of plasma-derived HIV-1 RNA. Nature Med. 1999;5:239-242.

Fang, G., Burger, H., Grimson, R., Tropper, P., Nachman, S., Mayers, D., Weislow, O., Moore, R., Reyelt, C., Hutcheon, N., Baker, D., and Weiser, B. Maternal plasma human immunodeficiency virus type 1 RNA level: a determinant and projected threshold for mother-to-child transmission, Proc. Natl. Acad. Sci. USA 1995;92:12100-12104.

Burger, H., Weiser, B., Flaherty, K., Gulla, J., Nguyen, P., and Gibbs, R.A. Evolution of human immunodeficiency virus type 1 nucleotide sequence diversity among close contacts.  Proc. Natl. Acad. Sci. USA 1991;88:11236-11240.

Weiser, B., Peress, N., Eilbott, D.J., La Neve, D., Seidman, R., and Burger, H. Human immunodeficiency virus type 1 expression in the central nervous system correlates directly with extent of disease. Proc. Natl. Acad. Sci. USA 1990;87:3997-4001.