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Department of Internal Medicine

Amparo C. Villablanca, M.D. View profile as PDF

Amparo C. Villablanca

Philosophy of Care

My philosophy of care is woman-centered and culturally sensitive, with respect for each patient.

Clinical Interests

Dr. Villablanca focuses on treating heart disease in women with the explicit goals of improving health-care outcomes and reducing gender-based health disparities.

Research/Academic Interests

Dr. Villablanca's research program involves investigating compounds like soy and natural estrogens to identify therapies for protecting heart health. She also conducts research on the molecular biology of sex hormones and sex steroid hormone receptors and their roles in vascular protection and regulating atherosclerosis susceptibility.

A leader in community-based research, Dr. Villablanca is actively engaged with grassroots organizations in developing outreach and education programs that improve risk factors for heart disease among populations most at risk.


Professor and Lazda Endowed Chair, Women's Cardiovascular Medicine
Director and founder, Women's Cardiovascular Medicine Program
Associate Director, Women's Center for Health
Director, Hormones and Atherosclerosis Laboratory, Center for Comparative Medicine


Cardiology, Cardiovascular Medicine, Internal Medicine


Internal Medicine


Cardiovascular Medicine


Lawrence J. Ellison Ambulatory Care Center
Cardiology Clinic
4860 Y St., Suite 0200
Sacramento, CA 95817
Driving Directions
Phone: 800-282-3284

Additional Phone:

Physician Referrals: 916-734-5678

Other Languages:

French, Spanish


M.D., UC Davis School of Medicine, Sacramento, California, 1983
B.S., UCLA, Los Angeles, California, 1979


UC Davis Medical Center, Sacramento, California, 1983-1984


UC Davis Medical Center, Sacramento, California, 1983-86


UC Davis Medical Center, Sacramento, California, 1987-90

Board Certifications:

American Board of Internal Medicine, 1987
American Board of Internal Medicine, Cardiovascular Disease, 1993

Professional Memberships:

American Heart Association (Fellow, Atherosclerosis, Thrombosis and Vascular Biology Council)
Mouse Biology Program (UC Davis)

Select Honors and Awards:

Health Care Hero, Sacramento Business Journal, 2013

Distinguished Scholarly Public Service Award, UC Davis Academic Senate, 2011

Helen Rodriguez-Trias Award for Excellence in Community-based Women’s Health Leadership, California Department of Health Care Services, 2009

UC Davis School of Medicine, Hibbard Williams Extraordinary Achievement Award, 2008

Heart of Gold Award, American Heart Association, 2007

Red Dress Award, Woman’s Day magazine, 2004

Select Recent Publications:

Villablanca, A. C., Beckett, L.A., Li ,Y., Leatherwood, S., Gill, S.K., Giardina, E.V., Barron, C., Foody, J.M., Haynes, S., D'Onofrio, G. Outcomes of comprehensive heart care programs in high-risk women. Journal of Women's Health, 2010;19(7): 1313-1325.

Villablanca, A. C., Pinkerton, K.E., Rutledge, J.C. Maternal and neonatal exposure to environmental tobacco smoke increases pro-inflammatory genes in neonatal arteries. Journal Cardiovascular Translational Research, 2010 Oct 2(Epub: ahead of print).

Villablanca, A.C., Muthuvel, J., Banka, C. Atherosclerosis and sex hormones: Current concepts. Invited Review. Clinical Science, 2010;119(12): 495-513.

Villablanca, A.C., Arline, S., Lewis, J., Raju, S., Sanders, S., Carrow, S. Outcomes of national community organization cardiovascular prevention programs for high-risk women. Journal of Cardiovascular Translational Research, 2009;2(3), p306.

Villablanca, A. C., Tenwolde, A., Lee, M., Huck, M., Mumenthaler, S., Rutledge, J.C. 17ß estradiol prevents early stage atherosclerosis in estrogen receptor-alpha deficient female mice. Journal of Cardiovascular Translational Research, 2009;2: 289-299.

Villablanca, A.C., Baxi, H., and Anderson, K. Novel Data Interface for Evaluating Cardiovascular Outcomes in Women. Handbook of Research on Information Technology Management and Clinical Administration in Healthcare. Dwivedi, A. (ed). IGI Publishing 1,142 pp; May 2009.

Bukkapatnam, R.N., Berglund, L., Anuurad, E., Devaraj, S., Hyson, D., Rafii, F., Malmstein, C., Villablanca, A. C. Postprandial metabolic responses to dietary glycemic index in hypercholesterolemic postmenopausal women. Preventive Cardiology, 2009;13(1): 29-35.

Foody, J.M., Villablanca, A. C., Giardina, E.V., Gill, S., Taylor, A.L., Leatherwood, S., Haynes, S.G., D'Onofrio, G. The office on women's health initiative to improve women's heart health: Program description, site characteristics and lessons learned. Journal of Women's Health, 2009;19(3): 507-516.

Corbacho, AM, Eiserich, JP, Zuniga, LA, Valacchi, G, Cross, CE, and Villablanca, AC. Compromised Aortic Vasoreactivity in Male Estrogen Receptor-Alpha Deficient Mice During Acute Lipopolyssacharide-Induced Inflammation. Encocrinology. Mar;148(3):1403-11, 2007.

Benton, J., Powers, A., Eiselein, L., Fitch, R., Wilson, D., Villablanca, A.C., and Rutledge. J.C. Hyperglycemia and loss of ovarian hormones mediate atheroma formation through endothelial layer disruption and increased permeability. Am J Physiol Regul Integr Comp Physiol. Feb;292(2):R723-30, 2007.

Wang-Polagruto, J.,Villablanca, A.C., Polagruto, J, Lee, L.., Holt, RA., Schrader, H., Ensunsa, J., Steinberg, FM., Schmitz, H., and Keen, CL. Chronic Consumption of Flavanol-rich Cocoa Improves Endothelial Function and Decreases Vascular Cell Adhesion Molecule (VCAM-1) in Hypercholesterolemic Postmenopausal Women J. Cardiovascular Pharmacology, 47[Suppl 2]:S177-S186, 2006.

Villablanca, AC, D Lubhan, L Shelby, K Lloyd and S Barthold. Susceptibility to early atherosclerosis in male mice is mediated by estrogen receptor a (ERa). Atherosclerosis, Thrombosis and Vascular Biology, 24:1055-1061 (with journal editorial). Erratum in: Arterioscler Thromb Vasc Biol, 24(6):1055-1061.

Nandur, R, K Kumar and AC Villablanca. Cardiovascular actions of selective estrogen receptor modulators (SERMs) and phytoestrogens. Preventive Cardiology, 7:73-79. Invited review.

To see if Amparo C. Villablanca is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).