Marike Zwienenberg, M.D.

Marike Zwienenberg, M.D.


Pediatric Neurological Surgery



  • Assistant Professor
To see if Marike Zwienenberg is accepting new patients, or for assistance finding a UC Davis doctor, please call 800-2-UCDAVIS (800-282-3284).

Lawrence J. Ellison Ambulatory Care Center

4860 Y St., Suite 0100
Sacramento, CA 95817
Driving Directions

Primary Phone:

Additional Phone Numbers

Clinic Phone: 916-734-4300
Physician Referrals: 800-4-UCDAVIS (800-482-3284)

Philosophy of Care

Disorders affecting the brain and spine are often life-altering for patients and their families. Under these circumstances, selecting the optimal treatment strategy for a child is a complex decision process. As a neurosurgeon I strive to educate and empower parents to make these complex healthcare decisions so that they can best fulfill the needs of their child and family.

Clinical Interests

I specialize in pediatric neurosurgery with specific emphasis on the treatment of brain tumors, craniofacial disorders, epilepsy, spinal dysraphism, and traumatic brain injury. My research interests include studying the effects of injury to the developing brain and long term impact on neurological functioning. Current research projects include evaluation of the cognitive impact of radiation to the pediatric brain and amelioration of its effect by administration of oral selenium compounds. I am interested in the impact of moderate brain injury on the cognitive development of young children and teenagers. I am currently studying these effects in a pediatric brain injury model and am involved with the development of relevant injury models for the pediatric age group. Development of these models will allow us to better understand the pathophysiology of injury and develop more targeted future interventions.


Neurological Surgery
Pediatric Surgery

Center/Program Affiliation

UC Davis Children's Hospital


M.D., Erasmus University Rotterdam, Rotterdam, 1997


UC Davis Medical Center, Sacramento, California, 2006


St. Jude Children?s Research Hospital/Le Bonheur Children?s Medical Center, Memphis, Tennessee, 2006-07

Board Certifications

American Board of Neurological Surgery, 2012

Professional Memberships

American Association of Neurological Surgeons

Congress of Neurological Surgeons

Pediatric section of American Association of Neurological Surgeons

Select Recent Publications

Kaufman BA, Matthews AE, Zwienenberg-Lee M and SM Lew. Spinal dural closure with nonpenetrating titanium clips in pediatric neurosurgery. Journal of Neurosurgery (Pediatrics), 6(4): 359-363. 2010

Utter GH, Shahlaie K, Zwienenberg-Lee M and JP Muizelaar. Anemia in the setting of traumatic brain injury: The arguments for and against liberal transfusion. Journal of Neurotrauma, 28: 155-165. 2010

Sanford RA, Merchant TE, Zwienenberg-Lee M, Kun LE and FA Boop. Advances in surgical techniques for resection of childhood cerebellopontine angle ependymomas are key to survival. Childs Nerv Syst, 25: 1229-1240. 2009

Zwienenberg-Lee M, Hartman J, Rudisill N, Madden LK, Smith K, Eskridge J, Newell D, Verweij B, Bullock MR, Baker A, Coplin W, Mericle R, Dai J, Rocke D and JP Muizelaar. Balloon Prophylaxis for Aneurysmal Vasospasm (BPAV) Study Group. Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trial. Stroke (Journal of the American Heart Association), 39: 1759-1765. 2008

Zwienenberg-Lee M, Hartmann J, Rudisill N and JP Muizelaar. Endovascular management of cerebral vasospasm. Neurosurgery, 59(5 Suppl.): 139-147. 2006

Pang D, Tse HH, Zwienenberg-Lee M, Smith M and J Zovickian. The combined use of hydroxyapatite and bioresorbable plates to repair cranial defects in children. Journal of Neurosurgery (Pediatrics I), 102: 35-43. 2005

Pang D, Zwienenberg-Lee M, Smith M and J Zovickian. Progressive cranial nerve palsy following shunting of isolated fourth ventricle. Journal of Neurosurgery, 102: 326-331. 2005

Zwienenberg M, Gong QZ, Berman RF, Muizelaar JP, Lyeth BG.The effect of groups II and III metabotropic glutamate receptor activation on neuronal injury in a rodent model of traumatic brain injury. Neurosurgery. 2001 May;48(5):1119-26; discussion 1126-7.

Zwienenberg M, Muizelaar JP. Severe pediatric head injury: the role of hyperemia revisited. J Neurotrauma. 1999 Oct;16(10):937-43.

Recent Videos


Life's little miracles: The Figone family story